Navigation Links
Multiple Sclerosis Drug May Be Linked to Melanoma
Date:2/6/2008

Doctors report 2 cases of the deadly skin cancer developing in patients taking Tysabri

WEDNESDAY, Feb. 6 (HealthDay News) -- Almost immediately after a 46-year-old woman with multiple sclerosis received her first dose of the drug Tysabri, a mole that had been on her shoulder for years suddenly took on a dangerous new character.

It turned out to be a melanoma that spread like wildfire. The woman now has just a few months to live.

At almost the same time, a 45-year-old woman who also has multiple sclerosis developed melanoma in her retina after receiving several doses of Tysabri. She had a family history of melanoma and also had atypical moles on her body; the mole on her retina went back at least nine years.

Although these are just two -- albeit dramatic -- examples, the authors of a letter in the Feb. 7 issue of the New England Journal of Medicine are cautioning doctors who care for MS patients to keep this potential risk in mind.

"Neurologists who have patients who report a family history of melanoma or have funny moles should send them to a dermatologist first. Don't just start them on drugs [Tysabri]," said Dr. John Thomas Mullen, co-author of the letter and a surgical oncologist with Beth Israel Deaconess Medical Center, in Boston.

"I can't say it's cause-and-effect definitively because it's just an observation, but the first patient had had that mole forever. She took the drug and almost instantaneously the lesion changed," added Mullen, who saw both patients.

"We don't know if the two are related right now," said Patricia O'Looney, vice president of biomedical research at the National Multiple Sclerosis Society. "There are so many people taking Tysabri, we should go forward with caution... One should always consult with their doctor and go over their personal family history and decide what is best."

Tysabri (natalizumab), a monoclonal antibody that helps treat
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved

Page: 1 2 3

Related medicine news :

1. DNA vaccine against multiple sclerosis appears safe, potentially beneficial
2. New MRI finding sheds light on multiple sclerosis disease progressio
3. Genomic Health Announces Multiple Studies on Oncotype DX(TM) Presented at 2007 American Society of Clinical Oncology (ASCO) Breast Cancer Symposium
4. Emory researchers identify signaling protein for multiple myeloma
5. Study suggests brain tumors need treatment with multiple targeted drugs
6. Gene profiling can single out the worst cases of multiple myeloma and guide therapy
7. Cell-surface sugar defects may trigger nerve damage in multiple sclerosis patients
8. Multiple corticosteroid injections in pregnant women may increase cerebral palsy
9. Multiple Sclerosis Patients Find Dietary Treatment More Effective Than Pharmaceutical Regimens
10. IVF technique enables pregnancy without multiple births, Stanford researchers find
11. Ingenious Med Forms Multiple Billing Company Partnerships to Market Inpatient Practice Management Solutions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2014)... terminology, and the relevance of palliation in advanced ... randomized controlled trials (RCTs). This is the result ... Quality and Efficiency in Health Care (IQWiG), which ... Together with external experts, IQWiG analysed studies on ... malignant melanoma, and pancreatic cancer. For this purpose, ...
(Date:4/24/2014)... awarded one of 30 grants from the National Cancer ... Site in its new National Clinical Trials Network ... of investigators charged with distributing resources in a more ... system reflects recommendations from a 2010 Institute of ... goals:, Faster design, launch, and completion of ...
(Date:4/23/2014)... by Massachusetts General Hospital (MGH) investigators may lead to ... a serious medical problem use of fecal material ... the Clostridium difficile ( C. difficile ) ... the journal Clinical Infectious Diseases , the researchers ... donors unrelated to patients was as successful in curing ...
(Date:4/23/2014)... J. O,Shea, M.D., scientific director at the National Institute ... been named the 2014 recipient of the Ross Prize ... open-access journal Molecular Medicine . The award will ... Academy of Sciences in Manhattan, followed by scientific presentations ... part of the National Institutes of Health. , The ...
(Date:4/23/2014)... researchers have identified an important enzyme pathway that helps ... few chromosomes, a condition that has been directly linked ... professor of biochemistry, found that near the end of ... that ensures any breaks in DNA are fully repaired ... to daughter cells. This process helps safeguard against some ...
Breaking Medicine News(10 mins):Health News:Palliation is rarely a topic in studies on advanced cancer 2Health News:Palliation is rarely a topic in studies on advanced cancer 3Health News:Dartmouth awarded lead role in NCI clinical trials network 2Health News:Dartmouth awarded lead role in NCI clinical trials network 3Health News:Use of frozen material for fecal transplant successfully treats C. difficile infection 2Health News:Use of frozen material for fecal transplant successfully treats C. difficile infection 3Health News:NIH scientist to receive Ross Prize in Molecular Medicine 2Health News:Study identifies enzymes that help fix cancer-causing DNA defects 2
... of herbal products and medicines has the potential to reach ... the creation of exclusive export promotion zones (EPZ) across ... can be accelerated with the setting up of EPZs in ... rate of over 25 percent in countries like the US, ...
... as marijuana or ganja, can help in the treatment ... body tissues are attacked by its own immune system. ... University of Bonn, used tetrahydrocannabinol (THC), the active ingredient ... that it reduced skin allergies. ,However, the ...
... Today at the 61st Annual Meeting of the ... Cordis Corporation, announced the worldwide launch of the ... use in angioplasty procedures for patients with carotid ... a unique high-pressure expansion and low profile .014 ...
... better way to say "I love you" than showing your Dad ... come . This Father's Day, the American Diabetes Association (ADA) wants ... out by their doctor. ,More than 10 percent of all ... 2 diabetes, the most common form of the disease, can come ...
... number of suicide attempts among asylum seekers in Denmark has ... of despair," according to a study published Thursday . ... camps -- or 0.6 percent of the total -- tried ... by the Danish Association to Help Refugees said. ...
... for a new study has found that regular practice ... as well as the cognitive decline associated with ... practice, is centred on attentional and postural self-regulation and ... normal age-related decline of cerebral gray matter volume and ...
Cached Medicine News:Health News:Export of Herbal Products to Reach Rs.120 Billion by 2012: Study 2Health News:New Balloon Catheter Available Worldwide for Carotid and Renal Angioplasty 2Health News:Drag Dad to the Doctor This Father's Day 2
(Date:1/15/2014)... Most osteoporosis patients want a choice in the medication ... by Mission Pharmacal Company. The survey, conducted by ... community, revealed that 74 percent of osteoporosis patients surveyed ... other than a pill or a tablet. ...
(Date:1/15/2014)... , Jan. 15, 2014  Novation, the leading health ... several new IT value-added reseller (VAR) national contracts that ... goods and services at lower costs. These include manufacturer ... such as initiative assistance and ongoing IT consulting support. ...
(Date:1/15/2014)...  Humberto C. Antunes,  Galderma  worldwide CEO, will receive a ... of Drugs in Dermatology (JDD) at the upcoming ... is January 17-20, 2014, at the Omni Orlando Resort at ChampionsGate ... The ODAC is a distinguished event that delivers a ...
Breaking Medicine Technology:Mission Pharmacal Conducts Online Survey of Osteoporosis Patients 2Mission Pharmacal Conducts Online Survey of Osteoporosis Patients 3New Novation Information Technology VAR Contracts Offer Significant Savings to Hospitals 2Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 2Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 3Galderma's global leader honored with a "Lifetime in Dermatology Achievement Award" by Journal of Drugs in Dermatology 4
... The ophthalmic therapeutics company Xcovery Vision announced today that ... Ken Mandell, President and COO, will be speaking at ... Annual Meeting in Fort Lauderdale Florida, May 1-5, 2011. ... recounts his repeated success as founder of multiple ...
... Accuracy in radiation therapy demands careful targeting and ... Farber Center for Radiation Oncology , the first and ... is among the first treatment centers to adopt Elekta,s ... patient positioning system that enables clinicians to fine-tune ...
Cached Medicine Technology:Xcovery Vision Founders to Speak at ARVO 2011 2Robotic Couch Provides Extra Degree of Precision for Patients Undergoing Radiation Therapy for Cancer 2
... Aestiva/5 Pendant anesthesia machine offers proven ... range with the SmartVent ventilator. However, ... superior ventilation. Enhancements in flexibility, ergonomics ... in anesthesia delivery., ,The Aestiva/5 ...
With its integrated design and superior build quality each Prima SP is custom built to meet your requirements....
... Tegagel hydrogel wound filler and ... are amorphous hydrogel dressings specially formulated ... that has been shown to enhance ... formula meets clinical needs for management ...
Features various cylinder sizes and a simple two-handed pumping mechanism....
Medicine Products: