Navigation Links
Multi-functional anti-inflammatory/anti-allergic developed by Hebrew University researcher
Date:9/6/2012

re biochemical mechanisms. A key one among them is the action of an enzyme family (PLA2) that initiates the production of a cascade of pro-inflammatory mediators involved in the induction and propagation of the diverse inflammatory diseases.

In Prof. Yedgar's lab at the Hebrew University, he and his associates have designed and constructed an entirely novel synthetic generation of drugs that control the PLA activity and the subsequent cascade of pro-inflammatory mediators, thereby providing multi-functional, anti-inflammatory drugs (MFAIDs).

MFAIDs have shown excellent safety and were found efficient in treating diverse inflammatory/allergic conditions in animal models, using different ways of administration oral, rectal, intravenous, inhaled and injected. These conditions included sepsis, inflammatory bowel diseases, asthma and central nervous system inflammation.

In particular, in two clinical studies MFAIDs have been shown to be safe and efficient in treating contact dermatitis, when incorporated into skin cream, and allergic rhinitis, when administered as a nasal spray.

This platform technology has been exclusively licensed from the Hebrew University through the university's Yissum Technology Transfer Company to Morria Biopharmaceuticals PLC (a British company), which is currently developing these drugs to treat inflammatory diseases of the airways (hay-fever, cystic fibrosis), the skin (eczema), the eye (conjunctivitis) and the gut (colitis, Crohn's disease).

For his groundbreaking work, Prof. Yedgar was one of the winners of this year's Kaye Innovation Awards at the Hebrew University. The Kaye Awards have been given annually since 1994. Isaac Kaye of England, a prominent industrialist in the pharmaceutical industry, established the awards to encourage faculty, staff and students of the Hebrew University to develop innovative methods and inventions with good commercial potential which will benefit the universit
'/>"/>

Contact: Jerry Barach
jerryb@savion.huji.ac.il
972-258-82904
The Hebrew University of Jerusalem
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Heroes of Chemistry: Developed new drugs and technology to cut heating and cooling bills
2. Clinical trials start for stroke drug developed by Scripps Research, USC, and ZZ Biotech
3. New Facebook app to detect pedophiles and criminals developed by Ben-Gurion U. researchers
4. National Actos Attorneys File Lawsuit on Behalf of Louisiana Woman who Developed Bladder Cancer Allegedly Due to The Diabetes Drug Actos
5. FDA clears test developed in partnership with VCU researcher
6. AGA releases first independently developed ABIM-approved Practice Improvement Module in GI
7. Power generation technology based on piezoelectric nanocomposite materials developed by KAIST
8. Research shows efficacy of treatment model developed at Women & Infants
9. University of Hawaii cancer researchers discover gene defect responsible for cancer syndrome
10. Oxford University Press acquires American Journal of Hypertension
11. Queens University Belfast wins national environment award
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Multi-functional anti-inflammatory/anti-allergic developed by Hebrew University researcher
(Date:12/20/2014)... Dec. 20, 2014 (HealthDay News) -- The holidays can ... they contend with fresh trees, scented candles and other ... on the decorations that have been packed away in ... my allergy and asthma patients," Dr. Rachna Shah, an ... of Medicine, said in Loyola news release. Shah, ...
(Date:12/20/2014)... New York (PRWEB) December 20, 2014 ... continue to move forward in U.S. courts, Bernstein ... study which suggests that children treated with the ... hormone linked to breast development and lactation. The ... at 34 children and adolescents who began treatment ...
(Date:12/20/2014)... December 20, 2014 Developers of ... of a new plugin for Final Cut Pro X ... “TranSlice Volume 5 allows users to create hand drawn ... Said Christina Austin, CEO of Pixel Film Studios. “TranSlice ... professionalism while maintaining an easy to use interface.” , ...
(Date:12/20/2014)... Today, Balfleet.com, one of the most outstanding dressmakers ... off on its Mother of the Bride Dresses ... the bride dresses from Balfleet.com feature gorgeous looks and ... takes pride in providing high quality dresses to its ... discounts on our mother of the bride dresses, and ...
(Date:12/19/2014)... Sarasota, Florida (PRWEB) December 19, 2014 Sub ... Bank to sponsor a blood drive Sunday the 28th from ... Clark Road & Sawyer Road in Sarasota, FL. , Inquiries ... special thank you for participating in the donating process, Sub ... a free flash frozen, custom ice cream. , About Sub ...
Breaking Medicine News(10 mins):Health News:Holiday Trimmings Can Trigger Allergies 2Health News:Risperdal Lawsuit News: Bernstein Liebhard LLP Notes Publication of Study Suggesting Medication May Raise Prolactin Levels in Children 2Health News:Risperdal Lawsuit News: Bernstein Liebhard LLP Notes Publication of Study Suggesting Medication May Raise Prolactin Levels in Children 3Health News:Risperdal Lawsuit News: Bernstein Liebhard LLP Notes Publication of Study Suggesting Medication May Raise Prolactin Levels in Children 4Health News:Pixel Film Studios released a new transition entitled TranSlice Volume 5 exclusively for Final Cut Pro X 2Health News:Balfleet.com is Offering 50%-70% Off of its Mother of the Bride Dresses 2Health News:Shark Tank’s Sub Zero Ice Cream Sponsors Blood Drive 2
... SATURDAY, Aug. 20 (HealthDay News) -- Working moms are less ... new study finds. However, working moms who don,t cut ... it will be to balance work and family have higher ... Researchers analyzed survey results from 1,600 married U.S. women who ...
... discovered a key mechanism used by intestinal cells to ... hospital-acquired bacterial infections a mechanism they think they ... the effects of the antibiotic-resistant bacteria. The scientists ... powerful toxins generated by the bacteria Clostridium difficile ...
... Aug. 20 (HealthDay News) -- Medications can be harmed by ... of drugs have been tested at temperatures above 86F, all ... According to Dr. Amy Peak, clinical pharmacist and director ... been tested at high temperatures. She outlined some of the ...
... , FRIDAY, Aug. 19 (HealthDay News) -- ... respiratory illnesses have pertussis, a highly contagious childhood disease ... The findings should reassure doctors they aren,t ... a distinctive-sounding and uncontrollable cough. In conducting the ...
... to 24 is rising rapidly according to a study conducted by ... The study appears in the "First Look" online version of ... increased popularity of the hookah a water pipe used for ... the behavior coupled with the misguided belief that it is less ...
... Reporter , FRIDAY, Aug. 19 (HealthDay News) -- At 3 years ... had quit growing. He also had frequent severe constipation, so much ... mother, Andrea Levario of Alexandria, Va. Because of the prolapse, ... from the body, doctors worried that the boy, who is now ...
Cached Medicine News:Health News:Trying to Be 'Supermom' Can Raise Risk for Depression 2Health News:Trying to Be 'Supermom' Can Raise Risk for Depression 3Health News:New defense discovered against common hospital-acquired infection 2Health News:Excessive Heat Can Harm Medications, Expert Says 2Health News:Kids' Hacking Is Seldom Whooping Cough, Study Finds 2Health News:UCSD researchers alarmed at rise in hookah use among California youth 2Health News:Gluten-Free Set This Boy Free 2
(Date:12/17/2014)... Germany , December 17, 2014 ... level of expenditure on research and development In ... increased its revenue by two percent to EUR 4.287 billion ... (EBIT) grew by 14 percent to EUR 360 million. "Overall, ... said Dr. Michael Kaschke , President and CEO of ...
(Date:12/17/2014)... December 17, 2014 , ... than a hub of information concerning the biopharmaceutical Group,s national ... A further addition to the recently launched institutional website that ... now been enriched by a new chapter in the fascinating ... A richly detailed and panoramic hub on the world of ...
(Date:12/17/2014)... PCCA received the Autism Hope Alliance,s ... program seal for best practices in meeting needs ... practices, materials and goods that meet strict criteria ... affected by autism often have unique physical or ... found in food and medicine – for instance ...
Breaking Medicine Technology:ZEISS Asserts its Position in Difficult Environment 2Dompé Offers a New "Window" on the World of Scientific Research, with the http://www.dompetrials.com Website, Dedicated to Clinical Trials 2Dompé Offers a New "Window" on the World of Scientific Research, with the http://www.dompetrials.com Website, Dedicated to Clinical Trials 3Parents Of Children With Autism Spectrum Disorder Have New Options When Administering Medications 2Parents Of Children With Autism Spectrum Disorder Have New Options When Administering Medications 3
... CITY, Calif., Dec. 7, 2011  Pearl Therapeutics Inc. ... double-blind, Phase 2b, dose-ranging study of glycopyrrolate, a ... via metered-dose inhaler (GP MDI; PT001) in patients with ... to placebo and Atrovent® HFA Inhalation Aerosol, a ...
... Dec. 7, 2011 Rigel Pharmaceuticals, Inc. (Nasdaq: ... company,s president and chief operating officer, is scheduled to ... Healthcare Conference in New York City on Wednesday, December ... http://photos.prnewswire.com/prnh/20030226/RIGLLOGO ) To access ...
Cached Medicine Technology:Pearl Therapeutics Reports Positive Phase 2b Results of PT001 in Patients With COPD 2Pearl Therapeutics Reports Positive Phase 2b Results of PT001 in Patients With COPD 3
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: