Navigation Links
Multi-center clinical study intensifies first strike at high-risk cancer in kids
Date:6/12/2012

CINCINNATI An experimental treatment that combines intense chemotherapy with a radioactive isotope linked to synthesized neurotransmitter is being tested in newly diagnosed cases of high-risk neuroblastoma a deadly, hard-to-cure childhood cancer.

The experimental radiopharmaceutical, 131I-MIBG, has already been tested in children with relapsed and resistant neuroblastoma, with encouraging results in reducing tumor size. This has prompted doctors in a new multi-center pilot clinical trial to see if their innovative combination therapy can help improve cure rates for newly diagnosed children and young adults, according to Brian Weiss, MD, trial chair and an oncologist at the Cincinnati Children's Hospital Medical Center.

Cure rates for neuroblastoma have plateaued at about 40 percent and new solutions are needed to improve outcomes, said Weiss, a member of the medical center's Cancer and Blood Diseases Institute.

"Unlike some diseases, there is no single detectable biological sign of neuroblastoma, so it's hard to catch early," he explained. "Children with relapsed disease usually don't survive more than a few years. We want to see if giving this more intensive treatment right after diagnosis will safely decrease the chances of the cancer coming back."

Neuroblastoma is one of the most commonly diagnosed childhood cancers, developing in nerve cells outside the brain. The cancer is usually first diagnosed by showing up as a lump or mass in the belly, or near the spinal cord in the chest or neck. The disease can spread to bone, the liver, lymph nodes and bone marrow. In high-risk neuroblastoma, the tumor has often spread from its primary site and is harder to treat.

MIBG stands for Meta-Iodo-Benzyl-Guanidine, a synthesized form of the adrenal gland hormone and neurotransmitter adrenalin. MIBG concentrates selectively in the body's sympathetic nervous system, which helps control glands and muscles. When attached to the
'/>"/>

Contact: Nick Miller
nicholas.miller@cchmc.org
513-803-6035
Cincinnati Children's Hospital Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Cleveland Clinic selected to participate in National MDS Clinical Research Consortium
2. Canada should significantly increase its funding of randomized clinical trials
3. Breast cancer clinical trial tests combo of heat shock protein inhibitor and hormonal therapy
4. Experts call for clinical trials to test non-skeletal benefits of vitamin D
5. Clinical news alert: Journal of the American Academy of Orthopaedic Surgeons May highlights
6. Automated insulin dosage titration system demonstrates positive clinical study results
7. Analysis Finds Clinical Trials Often Small, of Poor Quality
8. URMC clinical trial tests new regimen for hypertension
9. Association for Psychological Science, SAGE launch Clinical Psychological Science
10. Awards celebrate clinical research that can improve health and alleviate suffering
11. Kroenke honored for outstanding contributions in clinical research training
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/28/2014)... 28, 2014 On Monday, November 24, ... will present Feeding America Eastern Wisconsin with a check ... to donate a portion of proceeds to Feeding America ... “7 Days, 7 Ways to Save” with Turbana bananas ... were two for $4 and Turbana bananas were 29 ...
(Date:11/28/2014)... Dr. Paul Vitenas, one of the most ... Glow Holiday Event for those in the area that would like ... Glitter & Glow will take place on December 11, 2014, from ... the heart of Houston at 4208 Richmond Ave. , “We ... you will come and celebrate the season with us on December ...
(Date:11/28/2014)... Planning on seconds at Thanksgiving Day dinner this year? If ... reflux disease (GERD) -- a few steps may help minimize ... throat specialist at Lenox Hill Hospital in New York City, ... Pace yourself. Rather than have one ... day. It,s also a good idea to have a healthy ...
(Date:11/28/2014)... Los Angeles, CA (PRWEB) November 28, 2014 ... Tonight online, reported during the hugely popular, ... 24th, the antismoking organization Truth launched ground-breaking celebrity ... aged 18-49. The MTV viewership figures were estimated ... pointing Truth antismoking ads placed the spotlight on ...
(Date:11/28/2014)... (PRWEB) November 28, 2014 Lice Troopers Lice ... of its in-home head lice service for moms in ... the center of Coral Gables on Pone De-leon Blvd in ... Harbor Islands that service Miami-Dade & Broward. Lice Troopers ... in South Florida which has been treating families for several ...
Breaking Medicine News(10 mins):Health News:Turbana Partners With Sendik's Food Market to Donate $11,500 to Local Hunger-Relief Non-Profit 2Health News:Turbana Partners With Sendik's Food Market to Donate $11,500 to Local Hunger-Relief Non-Profit 3Health News:Cosmetic Surgeon Dr. Paul Vitenas to Host Glitter & Glow Holiday Event 2Health News:Cosmetic Surgeon Dr. Paul Vitenas to Host Glitter & Glow Holiday Event 3Health News:Don't Let Chronic Heartburn Spoil Your Thanksgiving Feast 2Health News:Freedom Laser Therapy Applauds American Legacy’s Creative Advertising Targeting Celebrity Smokers 2Health News:Freedom Laser Therapy Applauds American Legacy’s Creative Advertising Targeting Celebrity Smokers 3Health News:Freedom Laser Therapy Applauds American Legacy’s Creative Advertising Targeting Celebrity Smokers 4Health News:Freedom Laser Therapy Applauds American Legacy’s Creative Advertising Targeting Celebrity Smokers 5Health News:Lice Troopers Lice Removal Service Expands in Miami-Dade 2
... Additional leadership needed to manage growthWAYNE, Pa. March 10 ... software, workflow tools and consulting services, is adding two ... line in order to best manage its growing client ... Vice President of Audit and Education Services and James ...
... 10 More physician leaders are embracing technological advances, ... them clunky and unresponsive to their needs.Those are the ... College of Physician Executives (ACPE). The findings were published ... ACPE,s journal of medical management.ACPE conducted the same survey ...
... LCAV ) today announced that following a rigorous clinical comparison ... to reduce the number of platforms at each of its ... The Company expects this will reduce annual operating expenses in ... no later than the end of the third quarter of ...
... 10, 2009 Forest Laboratories, Inc. (NYSE: FRX ... KGaA, and Merz Pharmaceuticals GmbH announced today that the U.S. ... Determination granting the full five years of patent term extension ... listed in the U.S. Food and Drug Administration Orange Book ...
... Safety Week, the spotlight shifts to the 30,000 dental assistants ... who help ensure that sedation dentistry is as safe for ... much an all-team responsibility," says Dr. Michael Silverman, national chairman ... sedation dentistry educators. , ...
... signs multi-year agreement with PureWellness to provide comprehensive employee wellness program ... ... 2009 -- PureWellness, Inc, a leading provider of online wellness solutions, ... in Plano, TX, to provide a comprehensive online wellness program for ...
Cached Medicine News:Health News:Precyse Solutions Adds Executives, Realigns Around Service Lines 2Health News:Survey Results: Health Care Technology Advances as Physician Frustration Grows 2Health News:LCA-Vision New Excimer Laser Strategy to Reduce Operating Expenses in Excess of $3 Million Annually 2Health News:LCA-Vision New Excimer Laser Strategy to Reduce Operating Expenses in Excess of $3 Million Annually 3Health News:LCA-Vision New Excimer Laser Strategy to Reduce Operating Expenses in Excess of $3 Million Annually 4Health News:USPTO Issues Notice of Final Determination for Patent Term Extension for NAMENDA(R) 2Health News:Sedation Dentistry Safety Week Spotlights the Important Role of Dental Team Members 2Health News:Sedation Dentistry Safety Week Spotlights the Important Role of Dental Team Members 3Health News:Global Leader in Information Technology Services and Business Solutions Signs Long-Term Agreement with PureWellness 2Health News:Global Leader in Information Technology Services and Business Solutions Signs Long-Term Agreement with PureWellness 3
(Date:11/27/2014)... - New Solution That Makes ... JIN Co., Ltd. will launch JINS MEME "ACADEMIC PACK" ... yen or $5,000 (without tax /including two pairs of JINS ... a dedicated solution of "JINS MEME" to academic researchers, and ... generated by electrooculography and six-axis sensors without API. (*Physiological data ...
(Date:11/26/2014)... Mass. , Nov. 26, 2014   ... AEX: PHIA) today announced expanded availability of its ... DuraDiagnost, DigitalDiagnost, MobileDiagnost wDR, MobileDiagnost Opta[i] , ProGrade ... these solutions now available in the U.S., and ... markets, the portfolio offers Philips, customers innovative solutions ...
(Date:11/26/2014)... , Nov. 26, 2014  Perrigo Company plc ... global provider of "Quality Affordable Healthcare Products®," today announced ... relating to the sale of 6,809,210 ordinary shares at ... the full exercise of the option to purchase up ... Securities LLC and Barclays Capital Inc., as representatives of ...
Breaking Medicine Technology:JIN to Launch JINS MEME ACADEMIC PACK in Late April 2015 2JIN to Launch JINS MEME ACADEMIC PACK in Late April 2015 3Philips expands global reach of diagnostic X-Ray solutions 2Philips expands global reach of diagnostic X-Ray solutions 3Perrigo Company plc Announces The Closing Of Its Registered Public Offering Of Ordinary Shares 2Perrigo Company plc Announces The Closing Of Its Registered Public Offering Of Ordinary Shares 3Perrigo Company plc Announces The Closing Of Its Registered Public Offering Of Ordinary Shares 4
... DALLAS , June 21, 2010 ... store. , , , ... Cardiovascular Devices Market Outlook to 2016 (, http://www.reportsandreports.com/market-reports/netherlands-cardiovascular-de ,vices-market-outlook-to-2016/) , ... (Due to the length of these ...
... 21 Medco Health Solutions, Inc. (NYSE: MHS ) and ... joint venture with a long-term goal of improving patient health and helping to ... , , ... , , ...
Cached Medicine Technology:Cardiovascular Devices Market Outlook June Update by ReportsandReports 2Cardiovascular Devices Market Outlook June Update by ReportsandReports 3Cardiovascular Devices Market Outlook June Update by ReportsandReports 4Cardiovascular Devices Market Outlook June Update by ReportsandReports 5Cardiovascular Devices Market Outlook June Update by ReportsandReports 6Cardiovascular Devices Market Outlook June Update by ReportsandReports 7Cardiovascular Devices Market Outlook June Update by ReportsandReports 8Cardiovascular Devices Market Outlook June Update by ReportsandReports 9Cardiovascular Devices Market Outlook June Update by ReportsandReports 10Medco and Celesio Announce Pan-European Joint Venture to Enhance Quality of Clinical Care and Reduce Overall Healthcare Costs 2Medco and Celesio Announce Pan-European Joint Venture to Enhance Quality of Clinical Care and Reduce Overall Healthcare Costs 3Medco and Celesio Announce Pan-European Joint Venture to Enhance Quality of Clinical Care and Reduce Overall Healthcare Costs 4Medco and Celesio Announce Pan-European Joint Venture to Enhance Quality of Clinical Care and Reduce Overall Healthcare Costs 5Medco and Celesio Announce Pan-European Joint Venture to Enhance Quality of Clinical Care and Reduce Overall Healthcare Costs 6Medco and Celesio Announce Pan-European Joint Venture to Enhance Quality of Clinical Care and Reduce Overall Healthcare Costs 7
1000 L, Bulk Recommended for 500 and 1000 L pipettes....
Inquire...
... way to order tips. Each box contains 1000 ... which contains 200 tips (4 bags of 50 ... of 200 tips per pack. Bulk Packs are ... be opened for quick access to Gilsons Diamond ...
... Finntips have been designed to optimize the ... of our tip products is widely recognized ... range has been extended over the years ... standard and special tips including filter tips, ...
Medicine Products: