Navigation Links
Moving beyond embryonic stem cells: Encouragement on the horizon
Date:7/5/2011

ROCHESTER, Minn. For nearly two decades, the medical world and the American public have grappled with the lightning-rod topic of stem cells, in particular the controversy surrounding cells from human embryos. But when researchers four years ago successfully "reprogrammed" adult body cells to become stem cells, some thought the ethical debate was nearly over. Those redirected cells, known as induced pluripotent cells, or iPS cells, show potential as therapy.

"The benefit is they require no destruction of human embryos," says Mayo Clinic hematologist/oncologist C. Christopher Hook, M.D., an author reviewing the science and ethics of stem cell technologies in the July issue of Mayo Clinic Proceedings. "The hope is that these cells may make embryonic stem cells unnecessary, but, according to the stem cell scientists, we're not there yet."

Scientists who specialize in stem cells continue to regard embryo-derived cells as the gold standard among stem cells in pluripotency, the capacity to become any tissue in the body. Other stem cell technologies have benefits: Blood, bone marrow, and umbilical cord cells contain stem cells that treat leukemia and other blood cancers, but because they are adult stem cells lacking pluripotency, they've shown limitations as universal regenerative therapies. The newcomers on the scene, iPS cells, can be taken directly from each patient and genetically redirected to replace ailing cells, avoiding immune rejection or the need for existing embryos or eggs to create embryos.

Hook cautions that there are still challenges with iPS cells, and the public shouldn't expect therapies to roll out in the next year or so.

"One of the problems with the history of stem cell technologies in general has been the unrealistic hype and promise of therapies far faster than the science could produce," Hook says.

In an editorial in the same issue, medical geneticist Andre Terzic, M.D., Ph.D., the Marriott Family Professor of Cardiovascular Research at Mayo Clinic, states that iPS technology may not have reached fruition, but is invaluable for learning about diseases and testing new treatments.

"We need to accelerate the pace of this research, and speed discoveries in regenerative medicine to help patients," Terzic says.

Worldwide, however, state-of-the-art research still depends on embryonic stem cells, at least in serving as a biological yardstick.

"This is a topic that remains charged and highly politicized," Hook says. "Some claim the controversy about the need for embryonic stem cells should now be resolved. Hopefully, in time, with iPS's the perceived need for and use of human embryonic stem cells will rapidly become obsolete, but, according to many in the scientific community, we're far from being done with them. There may be another option in the use of these new cells, but it's going to take time."


'/>"/>

Contact: Rebecca Eisenman
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

Related medicine news :

1. Miles for Hope’s Moving Towards A Cure(SM) Brain Tumor Walk in Boston Raising Funds for Brain Tumor Vaccine and Massachusetts General Hospital
2. Minnesota Moving Company, Barrett Moving & Storage Launches New Online Look at www.barrettmoving.com
3. Moving Closer to a Urine Test for Colon Cancer
4. Active and healthy schools get kids moving
5. University of Colorado Hospital Moving Forward with $400 Million Expansion
6. Moving repeatedly in childhood linked with poorer quality-of-life years later
7. Wii Games Can Get Seniors Moving
8. Removing Gallbladder Sooner Cuts Costs, Readmissions
9. Watchful Waiting Often Best Strategy for Slow-Moving Prostate Cancer
10. Moving On With A Pen
11. Get Moving Can Be Vital Advice for Seniors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/6/2016)... ... February 06, 2016 , ... ... PERIOPERATIVE NURSES EXPECTED AT AORN SURGICAL CONFERENCE & EXPO , WHAT:     , ... with an estimated 5000 perioperative nurses in attendance to study the latest ...
(Date:2/6/2016)... ... 2016 , ... With the FCPX LUT: Summer pack from Pixel ... A LUT is a Lookup Table that contains a mathematical formula for modifying an ... table. By manipulating each pixel, LUT's can change each color range differently, it gives ...
(Date:2/6/2016)... ... February 06, 2016 , ... Research has shown that ... reduce the frequency and level of relapse. , At the 2016 ... Purpose,” will explore the critical tasks of the recovery phase and beyond including ...
(Date:2/5/2016)... ... 05, 2016 , ... Love is in the air at King Kullen! The ... and packaging. This staple for Valentine’s Day is a must-have, and can be picked ... Day, not only are long-stem roses available, but also other flower bouquets, elegantly wrapped ...
(Date:2/5/2016)... ... February 05, 2016 , ... Today, the Whole-Food Warrior TV ... the much-anticipated feature with author Jahnavi Foster, specialist in healthy vegetarian cuisine, will stream ... Each week, on his weekly Whole-Food Warrior TV show, Frank Davis highlights Whole-Food Warriors ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... , Feb. 5, 2016 Aethlon Medical, Inc. ... , Chairman and CEO, will be presenting at Source Capital ... New York, NY at 2:15 p.m. ET on ... an Immunotherapy Panel discussion taking place at 3:15 p.m. ET. ... replay approximately one hour after the conclusion of the live ...
(Date:2/5/2016)... 5, 2016 --> ... states that the global active pharmaceuticals ingredients (APIs) market ... to reach US$185.9 bn by 2020. It is expected ... to 2020. The title of the report is "Active ... Geography, and by Therapeutic Area) - Global Industry Analysis, ...
(Date:2/5/2016)... WARSAW, Ind. , Feb. 5, 2016  Zimmer ... the pricing of the previously announced underwritten secondary offering ... of its stockholders, consisting of affiliates of Blackstone and ... public at an initial price of $96.45 per share. ... of the offering.  Neither Zimmer Biomet nor any of ...
Breaking Medicine Technology: