Navigation Links
Move Cautiously in Approving New Obesity Drugs, Pulmonary Hypertension Association Says

Silver Spring, MD (PRWEB) June 24, 2013

The American Medical Association’s decision* to regard obesity as a disease is making top headlines this week, but in fact this is not the first time American health care has taken this view, according to the Pulmonary Hypertension Association (PHA). “In the 1990s, the results for too many who took prescription treatments for obesity were disastrous, resulting in a 6-fold increase in the incidence of life-threatening pulmonary hypertension,” said PHA president Rino Aldrighetti.

Two prescription weight loss drugs – fenfluramine and dexfenfluramine (also known as Redux, Pondimin and Fen-Phen) – were pulled from the market in 1997 after they were found to be associated with heart-valve problems. These drugs also resulted in increased incidence of pulmonary hypertension, or high blood pressure in the blood vessels between the heart and lungs. In cases of PH, these vessels narrow and stiffen, requiring the heart to work too hard to pump enough oxygenated blood to the body. Patients experience shortness of breath, chest pain, fainting, fatigue, and swelling of the legs and ankles. PH can make even daily activities such as walking difficult and limits thousands of patients’ ability to work, care for their homes and families and enjoy leisure activities.

Research published in 2002 showed that patients who took fenfluramine and dexfenfluramine developed PH after taking the drug for as little as 23 days. Those on the drug more than 3 months faced a 23-fold greater risk.

“This disease caused tremendous suffering and many premature deaths which might have been prevented if the effects of these drugs had been more carefully researched and disclosed. It’s essential that we avoid making this mistake again,” Aldrighetti said. “The last ‘war on obesity’ was driven by a combination of worthy concern and marketing emphasizing profit more than health. Many patients paid the price. That story is well told by journalist Alicia Mundy who coined the term ‘Obesity Inc.’ in her book about the legal battle over Fen-Phen, Dispensing with the Truth.

“Obesity is indeed a major public health concern,” Aldrighetti said, “but we need to remember our history and temper our well-founded concern about obesity with good judgment about the overall safety of new drugs to help Americans lose weight.”

PHA recommends that all patients speak with their physicians before considering using weight loss supplements and medications. PHA also recommends that patients with PH consult with their PH specialists about the possibility of using these products.

The mission of the Pulmonary Hypertension Association is to find ways to prevent and cure pulmonary hypertension, and to provide hope for the pulmonary hypertension community through support, education, research, advocacy and awareness. To learn more about pulmonary hypertension and its effects, visit

* 6/18/2013 American Medical Association

Read the full story at

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Related medicine news :

1. Disrupted Sleep May Raise Risk for Obesity, Diabetes: Study
2. Obesitys Health Costs Double Earlier Estimates
3. Troubled Homes May Fuel Obesity in Girls
4. Childhood Obesity May Raise Odds of Adult Liver Cancer
5. Could the Childhood Obesity Epidemic Be Ebbing?
6. New research finds no association between white potato consumption (baked, boiled mashed) and obesity, Type 2 diabetes or systemic inflammation
7. Mayo Clinic: Obesity epidemic fueling rise in rheumatoid arthritis among women
8. Treating childhood obesity: A family affair
9. Rising Obesity Rates Might Mean More Rheumatoid Arthritis
10. Research May Point to New Obesity Treatments
11. U.S. Obesity Rate Set to Soar, Costing Billions: CDC
Post Your Comments:
(Date:11/24/2015)... ... ... Charitable giving is at its peak during the holidays. In fact, ... the year totalling over $358 billion in 2014. With more than 1.5 million ... individuals who want to “give back” during the holidays. , “With so many charities ...
(Date:11/24/2015)... ... November 24, 2015 , ... The hospitals ... to several aspects of orthopedic care. They have received recognition for excellence from ... orthopedic care. , Becker's Hospital Review selected hospitals for inclusion based on ...
(Date:11/24/2015)... Port Richey, FL (PRWEB) , ... November 24, 2015 , ... ... it deems a growing epidemic as deaths from prescription opioids in the United States ... heroin and cocaine. In 2013 alone, opioids were involved in 37 percent of all ...
(Date:11/24/2015)... ... November 24, 2015 , ... Serenity Point Rehabilitation, a holistic treatment center for ... with some of the staff members at their recovery center. The videos highlight some ... as some of the things that make their recovery program so unique. , “Making ...
(Date:11/24/2015)... (PRWEB) , ... November 24, 2015 , ... ... award at Cleveland University-Kansas City (CU-KC), in Overland Park, Kansas. Benson, ... Chiropractor and University President Carl S. Cleveland III on October 16. , “Katie ...
Breaking Medicine News(10 mins):
(Date:11/24/2015)... BOULDER, Colo. , Nov. 24, 2015 /PRNewswire/ ... announced that its Chief Executive Officer, Ron ... Annual Healthcare Conference in New York.  The public ... a webcast on the Array BioPharma website.Event:Piper Jaffray ... OfficerDate:  , Wednesday, December 2, 2015Time:1:30 p.m. Eastern ...
(Date:11/24/2015)... Nueva York , 24 de noviembre de ... del Avery Breathing Pacemaker System, se complace anunciar ... Ph.D. como consultor clínico. ... Foto -   ... Jonzon es un fisiólogo y consultor en neonatología ...
(Date:11/24/2015)... --> --> ... by Product Type (Bone Graft, Bine Graft Substitute, Platelet Rich ... Lumbar Interbody Fusion), End User, and Geography - Global Forecast ... at $1.90 Billion in 2014 and is expected to reach ... the forecast period of 2015 to 2020. Browse ...
Breaking Medicine Technology: