Navigation Links
Move Cautiously in Approving New Obesity Drugs, Pulmonary Hypertension Association Says
Date:6/24/2013

Silver Spring, MD (PRWEB) June 24, 2013

The American Medical Association’s decision* to regard obesity as a disease is making top headlines this week, but in fact this is not the first time American health care has taken this view, according to the Pulmonary Hypertension Association (PHA). “In the 1990s, the results for too many who took prescription treatments for obesity were disastrous, resulting in a 6-fold increase in the incidence of life-threatening pulmonary hypertension,” said PHA president Rino Aldrighetti.

Two prescription weight loss drugs – fenfluramine and dexfenfluramine (also known as Redux, Pondimin and Fen-Phen) – were pulled from the market in 1997 after they were found to be associated with heart-valve problems. These drugs also resulted in increased incidence of pulmonary hypertension, or high blood pressure in the blood vessels between the heart and lungs. In cases of PH, these vessels narrow and stiffen, requiring the heart to work too hard to pump enough oxygenated blood to the body. Patients experience shortness of breath, chest pain, fainting, fatigue, and swelling of the legs and ankles. PH can make even daily activities such as walking difficult and limits thousands of patients’ ability to work, care for their homes and families and enjoy leisure activities.

Research published in 2002 showed that patients who took fenfluramine and dexfenfluramine developed PH after taking the drug for as little as 23 days. Those on the drug more than 3 months faced a 23-fold greater risk.

“This disease caused tremendous suffering and many premature deaths which might have been prevented if the effects of these drugs had been more carefully researched and disclosed. It’s essential that we avoid making this mistake again,” Aldrighetti said. “The last ‘war on obesity’ was driven by a combination of worthy concern and marketing emphasizing profit more than health. Many patients paid the price. That story is well told by journalist Alicia Mundy who coined the term ‘Obesity Inc.’ in her book about the legal battle over Fen-Phen, Dispensing with the Truth.

“Obesity is indeed a major public health concern,” Aldrighetti said, “but we need to remember our history and temper our well-founded concern about obesity with good judgment about the overall safety of new drugs to help Americans lose weight.”

PHA recommends that all patients speak with their physicians before considering using weight loss supplements and medications. PHA also recommends that patients with PH consult with their PH specialists about the possibility of using these products.

The mission of the Pulmonary Hypertension Association is to find ways to prevent and cure pulmonary hypertension, and to provide hope for the pulmonary hypertension community through support, education, research, advocacy and awareness. To learn more about pulmonary hypertension and its effects, visit http://www.PHAssociation.org.

*http://www.ama-assn.org/ama/pub/news/news/2013/2013-06-18-new-ama-policies-annual-meeting.page 6/18/2013 American Medical Association

Read the full story at http://www.prweb.com/releases/2013/6/prweb10863990.htm.


'/>"/>
Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Related medicine news :

1. Disrupted Sleep May Raise Risk for Obesity, Diabetes: Study
2. Obesitys Health Costs Double Earlier Estimates
3. Troubled Homes May Fuel Obesity in Girls
4. Childhood Obesity May Raise Odds of Adult Liver Cancer
5. Could the Childhood Obesity Epidemic Be Ebbing?
6. New research finds no association between white potato consumption (baked, boiled mashed) and obesity, Type 2 diabetes or systemic inflammation
7. Mayo Clinic: Obesity epidemic fueling rise in rheumatoid arthritis among women
8. Treating childhood obesity: A family affair
9. Rising Obesity Rates Might Mean More Rheumatoid Arthritis
10. Research May Point to New Obesity Treatments
11. U.S. Obesity Rate Set to Soar, Costing Billions: CDC
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/18/2017)... ... August 18, 2017 , ... More than 20,000 pairs of shoes made their ... to an ambitious venture that conjoined the passions of an NBA star, a Liberty ... Liberty community. These shoes will save lives from the rampant infections transmitted through the ...
(Date:8/18/2017)... ... August 18, 2017 , ... ... a highly specialized asset-light logistics provider of complex transport solutions for mission-critical ... to purchase Unitrans International Corporation, a division of Roadrunner Transportation Systems, Inc. ...
(Date:8/18/2017)... ... August 18, 2017 , ... ... of “Vision & Hearing,” advocating for active, healthy lifestyles and highlighting the importance ... for individuals with hearing impairments and shares the latest innovations in hearing aid ...
(Date:8/18/2017)... ... August 18, 2017 , ... ... handheld devices. Through an educational webinar, they will present the line of epMotion ... to learn how easy you can automate everyday pipetting tasks. , Ideal for ...
(Date:8/18/2017)... ... August 18, 2017 , ... Hernandez Insurance ... to communities throughout the greater DC region, is inaugurating a “New Leash On ... local animals and training them to be companions for veterans in need. , ...
Breaking Medicine News(10 mins):
(Date:8/7/2017)... 7, 2017 Diplomat Pharmacy, Inc. (NYSE: ... as president, effective Aug. 7, 2017. ... to pursue other interests and will serve as president emeritus ... has served us in multiple leadership roles since he joined ... 2015 and has provided decisive, strategic leadership which continues to ...
(Date:8/4/2017)... CINCINNATI , Aug. 3, 2017  Agragen, ... science company active in the biopharmaceutical, nutraceutical, and ... its development of its lead drug candidates, AGR131.  ... a proinflammatory cytokine from the blood of patients ... psoriasis, and inflammatory bowel disease. ...
(Date:8/2/2017)... Ore. , Aug. 2, 2017  Life Flight Network ... Agreement. The agreement improves patient care and operational efficiency for ... Springfield , Cottage Grove , ... level medical transportation. PeaceHealth and Life Flight Network work collaboratively ... available during transport, or when a time sensitive emergency exists. ...
Breaking Medicine Technology: