Navigation Links
Mouse study: Real-time imaging device may improve surgery for congenital colon disease
Date:2/29/2008

LOS ANGELES (Feb. 29, 2008) Researchers at Cedars-Sinai Medical Center are developing a spectral imaging system that could result in shorter operating times for infants undergoing surgery for Hirschsprungs disease, according to a mouse study reported in the Journal of Biophotonics.

The study documents that in addition to its diagnostic potential, spectral imaging may provide an optical biopsy, allowing precise localization of a needed intervention.

Spectral imaging is based on the fact that light reflected from a target can be captured and measured by highly sensitive equipment to develop a characteristic signature based on wavelength. In this study, the colon tissue of six mice with the equivalent of Hirschsprungs disease was analyzed and compared to that of controls. With repeated measurements and calculations, unique signatures for normal tissue and for diseased tissue emerged.

Spectral imaging does not detect the presence or absence of ganglion cells themselves. Instead, the spectral signature reflects differences in the composition of normal and diseased tissue.

As a result of this study in laboratory mice, human clinical trials will be planned, providing spectral imaging for intraoperative decision-making in Hirschsprung's disease, a congenital condition affecting nerve cells of the large intestine. The technology, developed at Cedars-Sinais Minimally Invasive Surgical Technologies Institute (MISTI) is adaptable to other types of surgery.

Hirschsprungs usually affects specialized nerve (ganglion) cells in the lower portion of the large intestine, although the entire colon can be involved. Ganglion cells normally stimulate smooth muscle of the intestinal wall to push stool through the colon, but in sections where ganglia are missing (aganglionosis) the process comes to a halt, causing severe constipation that can lead to obstruction, massive infection and even death.

Estimated to affect one in 5,000
'/>"/>

Contact: Sandy Van
sandy@prpacific.com
800-880-2397
Cedars-Sinai Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Effectiveness of mouse breeds that mimic Alzheimers disease symptoms questioned
2. Mouse vision has a rhythm all its own
3. Mouse Study Gives Clues to Colitis
4. Mouse mammary tumor virus can replicate in human cells
5. A longer-living, healthier mouse that could hold clues to human aging
6. Gene Tweak Reverses Aging in Mouse Skin Cells
7. Mouse Model of Age-Related Macular Degeneration Developed
8. Seal Shield Introduces New Silver Seal Washable, Antimicrobial Mouse at HiMSS Healthcare Symposium
9. U of M study: Early treatment can reverse heart damage
10. New study: Pine bark reduces perimenopausal symptoms
11. U of M study: Health food supplement may curb addiction of pathological gamblers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/14/2014)... (PRWEB) July 14, 2014 The ... is now offering Lumineers and porcelain veneers. ... procedures that require more preparation and greater loss of ... tooth-shaped shells to conceal visible flaws on the tooth. ... work closely with patients to ensure they offer the ...
(Date:7/14/2014)... Being physically active in middle age appears to help ... of dementia, suggest the findings from two new studies. ... at various levels, especially in midlife, is beneficial for ... said in an Alzheimer,s Association news release. "These ... More research is needed to determine the extent and ...
(Date:7/14/2014)... California (PRWEB) July 14, 2014 ... - Ultra performance liquid chromatography or UPLC ... technique of liquid chromatography that involves the ... pressure conditions to separate chromatographic compounds. This ... facilitates faster detection and analysis of chromatography ...
(Date:7/14/2014)... 2014 Many people are unhappy with ... surgery to reduce a “double chin.” A new ... need to go under the knife. Jawflex is a ... muscles, therefore tightening the skin in that area and ... is used for facial exercise, double chin elimination and ...
(Date:7/14/2014)... 14, 2014 July 14, 2014 ... in enterprise-class cloud management, governance, and compliance software ... AvePoint software will be available to customers of ... , The hosting and value-added reseller ... following AvePoint solutions to new or existing customers: ...
Breaking Medicine News(10 mins):Health News:Encino Esthetic Dental Group is Now Offering Lumineers and Porcelain Veneers 2Health News:Staying Active May Help Prevent Dementia 2Health News:Need for Faster Sample Analysis Drives Demand for UPLC, According to New Trend Report Published by Global Industry Analysts, Inc. 2Health News:Jawflex | Double Chin Exercise for Double Chin Reduction 2Health News:AvePoint Works with Rackspace to Extend Vital Management Features to Hybrid SharePoint Deployments 2Health News:AvePoint Works with Rackspace to Extend Vital Management Features to Hybrid SharePoint Deployments 3
... cardiovascular nurse and allied professional are already at the ... disease, and Professor Christi Deaton, Chairperson of the ESC ... an even greater role given the complex needs of ... to prevent cardiovascular disease," says Professor Deaton, "and we ...
... Eight projects in the Miami-Dade and Monroe Counties ... on addressing transportation and mobility options for seniors as ... winning projects were chosen based on their innovation and ... Place" services.The grants were the result of a November ...
... at 10 Rockefeller Plaza through March 31, 2009 NEW ... the Alzheimer,s Association, New York City Chapter will raise ... is due to the generosity of EHE International which ... display in its window at 10 Rockefeller Plaza.This display ...
... stores, studies find , , FRIDAY, March 6 (HealthDay News) ... are much less likely to offer healthy foods than ... live matters in terms of your diet," said study ... Hopkins Bloomberg School of Public Health in Baltimore. "If ...
... Pharmaceuticals (NYSE: VRX ) today announced that its ... 2009 at 9:00 a.m. Eastern Time, at the Hilton Hotel ... Jersey 07078. The record date for stockholders entitled to ... Valeant , Valeant Pharmaceuticals International (NYSE: VRX ) ...
... March 6 Despite the downturn in the economy, ... a healthcare-staffing agency founded 27 years ago in New ... an inevitable rebound in the economy, ANS has undertaken ... serve and more aggressively pursue clients on the Gulf ...
Cached Medicine News:Health News:Nurses and allied professionals at heart of cardiovascular prevention and management programs 2Health News:Nurses and allied professionals at heart of cardiovascular prevention and management programs 3Health News:Miami-Dade and Monroe County Organizations Receive Grants to 'JumpStart the Conversation' 2Health News:Miami-Dade and Monroe County Organizations Receive Grants to 'JumpStart the Conversation' 3Health News:Miami-Dade and Monroe County Organizations Receive Grants to 'JumpStart the Conversation' 4Health News:EHE International Helps Alzheimer's Association, New York City Chapter to Raise Awareness About Alzheimer's Disease 2Health News:Healthy Foods Harder to Find in Poor Neighborhoods 2Health News:Healthy Foods Harder to Find in Poor Neighborhoods 3Health News:Healthy Foods Harder to Find in Poor Neighborhoods 4Health News:American Nursing Services, Inc. Expanding Eastern Presence, Opening Birmingham Office 2
(Date:7/14/2014)... July 14, 2014 CVS/pharmacy ® ... PLATINUM, a premium brand of 100% preservative-free vitamins ... growing family of exclusive CVS/pharmacy store brand products. ... with various benefits, including popular options such as ... women. The radiance PLATINUM line also has more premium options ...
(Date:7/14/2014)... , July 14, 2014 The legalization of ... – as well as a new economic driver – ... to sort out the right response to the will ... intoxicant. At a National Press Club ... a.m., two leading experts in the area of marijuana ...
(Date:7/14/2014)... N.Y. , July 14, 2014 We ... Surgery Center ("OACM") and the Ellicott City Ambulatory Surgery ... of Ellicott City Maryland . ... between Merritt Healthcare and 14 leading Orthopaedics, Sports Medicine, ... Facility will also accommodate the specialties of general surgery ...
Breaking Medicine Technology:CVS/pharmacy Launches Exclusive radiance PLATINUM Line of Preservative-Free Vitamins and Supplements 2CVS/pharmacy Launches Exclusive radiance PLATINUM Line of Preservative-Free Vitamins and Supplements 3NPC Newsmaker Program: Interpreting smoke signals from the marijuana skirmish line 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: