Navigation Links
Mouse study: Real-time imaging device may improve surgery for congenital colon disease
Date:2/29/2008

LOS ANGELES (Feb. 29, 2008) Researchers at Cedars-Sinai Medical Center are developing a spectral imaging system that could result in shorter operating times for infants undergoing surgery for Hirschsprungs disease, according to a mouse study reported in the Journal of Biophotonics.

The study documents that in addition to its diagnostic potential, spectral imaging may provide an optical biopsy, allowing precise localization of a needed intervention.

Spectral imaging is based on the fact that light reflected from a target can be captured and measured by highly sensitive equipment to develop a characteristic signature based on wavelength. In this study, the colon tissue of six mice with the equivalent of Hirschsprungs disease was analyzed and compared to that of controls. With repeated measurements and calculations, unique signatures for normal tissue and for diseased tissue emerged.

Spectral imaging does not detect the presence or absence of ganglion cells themselves. Instead, the spectral signature reflects differences in the composition of normal and diseased tissue.

As a result of this study in laboratory mice, human clinical trials will be planned, providing spectral imaging for intraoperative decision-making in Hirschsprung's disease, a congenital condition affecting nerve cells of the large intestine. The technology, developed at Cedars-Sinais Minimally Invasive Surgical Technologies Institute (MISTI) is adaptable to other types of surgery.

Hirschsprungs usually affects specialized nerve (ganglion) cells in the lower portion of the large intestine, although the entire colon can be involved. Ganglion cells normally stimulate smooth muscle of the intestinal wall to push stool through the colon, but in sections where ganglia are missing (aganglionosis) the process comes to a halt, causing severe constipation that can lead to obstruction, massive infection and even death.

Estimated to affect one in 5,000
'/>"/>

Contact: Sandy Van
sandy@prpacific.com
800-880-2397
Cedars-Sinai Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Effectiveness of mouse breeds that mimic Alzheimers disease symptoms questioned
2. Mouse vision has a rhythm all its own
3. Mouse Study Gives Clues to Colitis
4. Mouse mammary tumor virus can replicate in human cells
5. A longer-living, healthier mouse that could hold clues to human aging
6. Gene Tweak Reverses Aging in Mouse Skin Cells
7. Mouse Model of Age-Related Macular Degeneration Developed
8. Seal Shield Introduces New Silver Seal Washable, Antimicrobial Mouse at HiMSS Healthcare Symposium
9. U of M study: Early treatment can reverse heart damage
10. New study: Pine bark reduces perimenopausal symptoms
11. U of M study: Health food supplement may curb addiction of pathological gamblers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... 2015 A new white paper by ... person-centeredness in the long-term care environment as well as ... continuum. The paper, “The Power of Person-Centeredness in Long-Term ... practices of the patient, resident and family experience in ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Autocarinsurancebest.com has released ... purchasing a commercial auto insurance policy . , Auto ... their vehicles. It is no longer necessary to call an ... are now available online on a single website: http://autocarinsurancebest.com/ ...
(Date:1/22/2015)... Carinsurancesavings.biz has released a new blog post presenting the basic ... , Purchasing an accidental death and dismemberment rider for a ... rider provides benefits if the insured dies in an accident. ... of life insurance. , AD&D is not expensive and ...
(Date:1/22/2015)... NY (PRWEB) January 22, 2015 ... of Sports Medicine flagship journal Medicine & Science ... L-Citrulline before exercise may help reduce gastrointestinal (GI) ... 1 , Participants in the double-blind, placebo-controlled ...
(Date:1/22/2015)... Weddingshe.com has added many trendy Champagne wedding dresses ... in the past three years. Today, the business announces a ... to the sales manager of the company, this is on ... This point can be reflected on the discounted wedding dresses ...
Breaking Medicine News(10 mins):Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 3Health News:Commercial Auto Insurance Provides Several Important Features! 2Health News:Accidental Death and Dismemberment Insurance Can Be Purchased at Low Prices Online 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 3Health News:Weddingshe Announces A Special Offer On Its Popular Glamorous Wedding Dresses 2
... people with type 1 version of disease , WEDNESDAY, Aug. ... proteins may contribute to type 1 diabetes, Canadian researchers say. ... found that nearly half had immune system T-cells that overreacted ... abnormal immune response. , "The immune system has to find ...
... but actual amount still small , WEDNESDAY, Aug. 26 (HealthDay ... radiation Americans would otherwise be exposed to, new research shows. ... three-quarters of the exposure, and more than 80 percent of ... Fazel, senior author of a study appearing in the Aug. ...
... contribute to drug resistance in non-small cell lung cancer ... access journal BMC Cancer found good correlation ... and resistance and actual in vitro chemosensitivity. Ian ... team of researchers who assessed the chemosensitivity of a ...
... , DES MOINES, Iowa, Aug. 26 Briggs, the ... solutions to long term care facilities, today announced a unique program to ... certified nursing homes. , , Briggs, new ... in response to the five-star rating system implemented late last year by ...
... ... in cooperation with FDA and PhRMA, will host Progression-Free Survival Oncology Workshop from October ... ... Association (DIA), in cooperation with FDA and PhRMA, will host Progression-Free Survival ...
... 26 With this morning,s passing of Massachusetts Senator Ted Kennedy ... it could lead to quicker diagnoses for others affected by the ... In 2005, Grundner established The Kelly Heinz-Grundner Brain Tumor Foundation ... his position as Senior Vice President at JPMorgan Chase to dedicate ...
Cached Medicine News:Health News:Medical Scans a Significant Source of Radiation 2Health News:Medical Scans a Significant Source of Radiation 3Health News:Briggs Program Improves Care in Nation's Nursing Homes 2Health News:Briggs Program Improves Care in Nation's Nursing Homes 3Health News:DIA/FDA/PhRMA to Host Progression-Free Survival Oncology Workshop 2Health News:DIA/FDA/PhRMA to Host Progression-Free Survival Oncology Workshop 3
(Date:1/23/2015)... , Jan. 23, 2015  Mallinckrodt plc (NYSE: ... has approved a share repurchase program. The open-ended authorization ... of Mallinckrodt plc ordinary shares. "Funding ... top priorities as we continue to pursue a range ...
(Date:1/22/2015)... 22, 2015  ViewRay™, a privately held medical device company, ... distributor agreement with ITOCHU Corporation (Tokyo Stock Exchange TYO: ... the treatment of cancer in Japan ... world,s first and only MRI-guided radiation therapy system that ...
(Date:1/22/2015)... Therapeutics Inc. (OTCQX:PVTTF; CSE:PVO), ("Pivotal" or the "Company"), a specialty ... disease and overall health is pleased to provide you with ... outlook for 2015 from the CEO, Mr. Eugene Bortoluzzi ... like to take this opportunity to share with you the ...
Breaking Medicine Technology:Mallinckrodt plc Announces Share Repurchase Program 2Mallinckrodt plc Announces Share Repurchase Program 3Mallinckrodt plc Announces Share Repurchase Program 4ITOCHU Named the Exclusive Distributor for ViewRay's MRI-Guided Radiation Therapy System in Japan 2Pivotal Therapeutics: Year in Review and CEO Update 2Pivotal Therapeutics: Year in Review and CEO Update 3Pivotal Therapeutics: Year in Review and CEO Update 4Pivotal Therapeutics: Year in Review and CEO Update 5Pivotal Therapeutics: Year in Review and CEO Update 6Pivotal Therapeutics: Year in Review and CEO Update 7
... 31, 2011 AAIPharma Services Corp., a leading ... announced today the promotion of Dean Shirazi, Ph.D., ... the position effective April 4, 2011. ... Shirazi, who joined AAIPharma in June 1992 as ...
... Reportlinker.com announces that a new market research report ... Molecular Diagnostics in Infectious Disease Testing ... This TriMark Publications report describes the specific segment ... molecular diagnostics testing for infectious disease. In the ...
Cached Medicine Technology:AAIPharma Services Announces Promotion of Dean Shirazi 2Reportlinker Adds Molecular Diagnostics in Infectious Disease Testing 2Reportlinker Adds Molecular Diagnostics in Infectious Disease Testing 3Reportlinker Adds Molecular Diagnostics in Infectious Disease Testing 4Reportlinker Adds Molecular Diagnostics in Infectious Disease Testing 5Reportlinker Adds Molecular Diagnostics in Infectious Disease Testing 6Reportlinker Adds Molecular Diagnostics in Infectious Disease Testing 7Reportlinker Adds Molecular Diagnostics in Infectious Disease Testing 8Reportlinker Adds Molecular Diagnostics in Infectious Disease Testing 9Reportlinker Adds Molecular Diagnostics in Infectious Disease Testing 10Reportlinker Adds Molecular Diagnostics in Infectious Disease Testing 11Reportlinker Adds Molecular Diagnostics in Infectious Disease Testing 12Reportlinker Adds Molecular Diagnostics in Infectious Disease Testing 13Reportlinker Adds Molecular Diagnostics in Infectious Disease Testing 14Reportlinker Adds Molecular Diagnostics in Infectious Disease Testing 15Reportlinker Adds Molecular Diagnostics in Infectious Disease Testing 16Reportlinker Adds Molecular Diagnostics in Infectious Disease Testing 17Reportlinker Adds Molecular Diagnostics in Infectious Disease Testing 18
For the quantitative determination of direct bilirubin in human serum. Linearity: 20 mg/dl...
... microplate spectrophotometer designed specifically to run 24 ... With rugged hardware, proven optical performance and ... of traditional spectrophotometry to obtain results quickly, ... read up to eight, 1 cm Biocell ...
... The 1100RS Spectrophotometers ... economical. Great for use ... laboratories, including educational, clinical, ... Options include COD vial ...
Spectra 2000 Digital Spectrophotometer is designed for quantitative and qualitative analysis in visible range from 320 nm to 1020 nm....
Medicine Products: