Navigation Links
Mouse Study Uncovers the Roots of Gray Hair

THURSDAY, June 16 (HealthDay News) -- The roots of gray hair may lie in a particular type of communication between hair follicles and melanocyte stem cells, the cells that make and store the pigments in skin and hair, a new study suggests.

Using mouse models, researchers at NYU Langone Medical Center found that Wnt signaling, already known to control many biological processes, may explain how these stem cells work together to produce hair color and generate hair growth.

"We have known for decades that hair follicle stem cells and pigment-producing melanocycte cells collaborate to produce colored hair, but the underlying reasons were unknown," said Mayumi Ito, assistant professor of dermatology at NYU Langone in a news release from NYU. "We discovered Wnt signaling is essential for coordinated actions of these two stem cell lineages and critical for hair pigmentation."

Researchers found the lack of Wnt activation in melanocyte stem cells leads to de-pigmented, or gray hair. They also showed that abnormal Wnt signaling in hair follicle stem cells prevents hair re-growth. The study's authors concluded their findings could serve as a model for tissue regeneration.

"The human body has many types of stem cells that have the potential to regenerate other organs," noted Ito. "The methods behind communication between stem cells of hair and color during hair replacement may give us important clues to regenerate complex organs containing many different types of cells."

The researchers added the study, published in the June 11 issue of Cell, could help shed light on diseases in which melanocytes are either lost or grow uncontrollably as in melanoma.

More information

The U.S. Library of Congress has more on why hair turns gray.

-- Mary Elizabeth Dallas

SOURCE: NYU Langone Medical Center, news release, June 14, 2011

Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Mouse Study Reveals How Smoking Helps Keep People Thin
2. Apples Help Keep Muscles Strong, Mouse Study Finds
3. Scientists create humanized mouse model for hepatitis C
4. Pitt researchers build a better mouse model to study depression
5. Mouse study turns fat-loss/longevity link on its head
6. Fox Chase researchers report that naproxen reduces tumors in a mouse model of colon cancer
7. Sleeping through danger: the dormouse approach to survival
8. Mouse Sperm Successfully Grown in Lab, Researchers Say
9. Mouse cancer genome unveils genetic errors in human cancers
10. Malaria drug slows pancreatic cancer growth in mouse models
11. New mouse model explains common pediatric brain tumor
Post Your Comments:
(Date:11/27/2015)... ... November 27, 2015 , ... The ... of USA Today in Atlanta, Dallas, New York, Minneapolis, South Florida, with a ... component is distributed nationally, through a vast social media strategy and across a ...
(Date:11/27/2015)... ... November 27, 2015 , ... Consistent with ... the 2016 Building Better Radiology Marketing Programs meeting will showcase some ... March 6, 2016, at Caesars Palace in Las Vegas with a pre-conference session ...
(Date:11/27/2015)... ... 2015 , ... The moment you stop improving is the ... the needs of advisers and clients but going above and beyond to find ... service. However, there's always room for improvement, which is why the entire Consulting ...
(Date:11/27/2015)... ... November 27, 2015 , ... ... most successful and prominent nonprofit healthcare organizations in the country. They have overseen ... various organizations, and helped advance the healthcare industry as a whole through their ...
(Date:11/27/2015)... (PRWEB) , ... November 27, 2015 , ... ... contact center software Q-Suite, announces the incorporation of Asterisk 11 LTS (Long Term ... fully supported Asterisk 11 LTS brings Q-Suite 5.10 up-to-date with a version of ...
Breaking Medicine News(10 mins):
(Date:11/27/2015)... YORK , November 27, 2015 ... system is set to go online. The potential to ... processes is vast and far from fully exploited as ... to patient health records, either via mobile tablet or ... ) --> ) --> ...
(Date:11/26/2015)... , November 27, 2015 ... --> --> ... emergency response system (PERS) market ... for 5 years with APAC ... expected to see a high ...
(Date:11/26/2015)... 2015 --> --> ... to find optimal contrast weighting of MRI for patients ... signed a research agreement with SyntheticMR in order to use ... it is possible to generate multiple contrast images from a ... has left, thus making it possible to both fine tune ...
Breaking Medicine Technology: