Navigation Links
Mouse Study Uncovers the Roots of Gray Hair
Date:6/16/2011

THURSDAY, June 16 (HealthDay News) -- The roots of gray hair may lie in a particular type of communication between hair follicles and melanocyte stem cells, the cells that make and store the pigments in skin and hair, a new study suggests.

Using mouse models, researchers at NYU Langone Medical Center found that Wnt signaling, already known to control many biological processes, may explain how these stem cells work together to produce hair color and generate hair growth.

"We have known for decades that hair follicle stem cells and pigment-producing melanocycte cells collaborate to produce colored hair, but the underlying reasons were unknown," said Mayumi Ito, assistant professor of dermatology at NYU Langone in a news release from NYU. "We discovered Wnt signaling is essential for coordinated actions of these two stem cell lineages and critical for hair pigmentation."

Researchers found the lack of Wnt activation in melanocyte stem cells leads to de-pigmented, or gray hair. They also showed that abnormal Wnt signaling in hair follicle stem cells prevents hair re-growth. The study's authors concluded their findings could serve as a model for tissue regeneration.

"The human body has many types of stem cells that have the potential to regenerate other organs," noted Ito. "The methods behind communication between stem cells of hair and color during hair replacement may give us important clues to regenerate complex organs containing many different types of cells."

The researchers added the study, published in the June 11 issue of Cell, could help shed light on diseases in which melanocytes are either lost or grow uncontrollably as in melanoma.

More information

The U.S. Library of Congress has more on why hair turns gray.

-- Mary Elizabeth Dallas

SOURCE: NYU Langone Medical Center, news release, June 14, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Mouse Study Reveals How Smoking Helps Keep People Thin
2. Apples Help Keep Muscles Strong, Mouse Study Finds
3. Scientists create humanized mouse model for hepatitis C
4. Pitt researchers build a better mouse model to study depression
5. Mouse study turns fat-loss/longevity link on its head
6. Fox Chase researchers report that naproxen reduces tumors in a mouse model of colon cancer
7. Sleeping through danger: the dormouse approach to survival
8. Mouse Sperm Successfully Grown in Lab, Researchers Say
9. Mouse cancer genome unveils genetic errors in human cancers
10. Malaria drug slows pancreatic cancer growth in mouse models
11. New mouse model explains common pediatric brain tumor
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2017)... ... ... Ulster University, Magee Campus in Northern Ireland is hosting The Schools for ... to graduate students exciting new and innovative hope research based on iFred’s “Schools for ... Improvement Service of the Western Health & Social Care Trust (WHSCT) in partnership with ...
(Date:6/23/2017)... ... June 23, 2017 , ... Jusino Insurance Services, ... communities in the greater Chicago metropolitan area, is embarking on a charity drive ... in Chicago. , Founded in 1897, Hephzibah Children’s Association is one of the ...
(Date:6/23/2017)... ... 2017 , ... Radabaugh & Associates, a locally owned firm ... in North Central West Virginia, is embarking on a cooperative charity drive with ... the region. , The Stepping Stones organization offers a series of personal development ...
(Date:6/22/2017)... ... June 22, 2017 , ... Branches, Inc. has been ... $245,000 in grant funding to support its programs focused on providing opportunity to low-income ... awarded a grant by the Foundation of $15,000 to support its , Climb to ...
(Date:6/22/2017)... ... June 22, 2017 , ... United Benefit Advisors (UBA), ... & Company as its newest Partner Firm. Headquartered in Coconut Creek, Florida, Whipple ... while tailoring optimized benefit packages that strengthen the relationship between employer and employee. ...
Breaking Medicine News(10 mins):
(Date:6/1/2017)... June 1, 2017 Nutriceutical Holdings (NH), parent ... Solutions (VRS), and KD Pharma Group have decided to ... by KD Pharma Group. KD Pharma Group will become ... to acquire the entire company. "We believe ... are committed to growing the NH companies by providing ...
(Date:5/30/2017)... Hill-Rom Holdings, Inc. (NYSE: HRC), will present at ... on Tuesday, June 13, 2017, in Rancho Palos ... and chief executive officer, is scheduled to present at 3:20 ... be accessed at http://ir.hill-rom.com/events.cfm . A recorded replay will ... through September 13, 2017. ...
(Date:5/29/2017)... 29, 2017  Cellect Biotechnology Ltd. (NASDAQ: ... enables the functional selection of stem cells, today provided ... first quarter ended March 31 st , 2017. ... in the first quarter of 2017," said Dr. Shai ... announced the treatment of the first blood cancer patient ...
Breaking Medicine Technology: