Navigation Links
Mouse Study Uncovers the Roots of Gray Hair
Date:6/16/2011

THURSDAY, June 16 (HealthDay News) -- The roots of gray hair may lie in a particular type of communication between hair follicles and melanocyte stem cells, the cells that make and store the pigments in skin and hair, a new study suggests.

Using mouse models, researchers at NYU Langone Medical Center found that Wnt signaling, already known to control many biological processes, may explain how these stem cells work together to produce hair color and generate hair growth.

"We have known for decades that hair follicle stem cells and pigment-producing melanocycte cells collaborate to produce colored hair, but the underlying reasons were unknown," said Mayumi Ito, assistant professor of dermatology at NYU Langone in a news release from NYU. "We discovered Wnt signaling is essential for coordinated actions of these two stem cell lineages and critical for hair pigmentation."

Researchers found the lack of Wnt activation in melanocyte stem cells leads to de-pigmented, or gray hair. They also showed that abnormal Wnt signaling in hair follicle stem cells prevents hair re-growth. The study's authors concluded their findings could serve as a model for tissue regeneration.

"The human body has many types of stem cells that have the potential to regenerate other organs," noted Ito. "The methods behind communication between stem cells of hair and color during hair replacement may give us important clues to regenerate complex organs containing many different types of cells."

The researchers added the study, published in the June 11 issue of Cell, could help shed light on diseases in which melanocytes are either lost or grow uncontrollably as in melanoma.

More information

The U.S. Library of Congress has more on why hair turns gray.

-- Mary Elizabeth Dallas

SOURCE: NYU Langone Medical Center, news release, June 14, 2011


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Mouse Study Reveals How Smoking Helps Keep People Thin
2. Apples Help Keep Muscles Strong, Mouse Study Finds
3. Scientists create humanized mouse model for hepatitis C
4. Pitt researchers build a better mouse model to study depression
5. Mouse study turns fat-loss/longevity link on its head
6. Fox Chase researchers report that naproxen reduces tumors in a mouse model of colon cancer
7. Sleeping through danger: the dormouse approach to survival
8. Mouse Sperm Successfully Grown in Lab, Researchers Say
9. Mouse cancer genome unveils genetic errors in human cancers
10. Malaria drug slows pancreatic cancer growth in mouse models
11. New mouse model explains common pediatric brain tumor
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... Dickinson ... offers insurance and financial preparation services, is providing an update on a charitable ... , Rock City Rescue is a locally recognized nonprofit that provides shelter and ...
(Date:10/13/2017)... ... October 13, 2017 , ... PurhealthRX , a leading Health and ... Applying the Purzorb™process to full spectrum CBD oil will revolutionize the rapidly growing CBD ... that can be easily incorporated into liquid products, while reducing costs to end users. ...
(Date:10/13/2017)... ... ... The Visiting Nurse Association (VNA) of Somerset Hills is proud to host ... items from across the nation, this holiday-themed event will raise funds and awareness for ... The boutique will be open Saturday, November 4 (10:00 a.m. – 5:00 p.m.) ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... Agile Software Development, has been awarded a contract by the Center for Medicare ... (BPA) aims to accelerate the enterprise use of Agile methodologies in a consistent ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest ... its plans to open a flagship location in Covington, LA at 401 N. U.S. ... Go store next to Office Depot in the Holiday Square shopping center. Its location ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... MIAMI , Sept. 27, 2017  Commended for their ... recent notable awards. Ranked as number one in the South ... ninth time in Inc. 5000 yearly list, the national specialty ... CEO, Armando Bardisa will soon be honored by ... Set to receive his award ...
(Date:9/23/2017)... , Sept. 22, 2017 Janssen Biotech, Inc. ... response letter from the U.S. Food and Drug Administration ... of sirukumab for the treatment of moderately to severely ... additional clinical data are needed to further evaluate the ... severely active RA. ...
(Date:9/19/2017)... Ky. , Sept. 19, 2017   ZirMed Inc ... predictive analytics, today announced that it has been ranked #1 ... Black Book™ Rankings 2017 User Survey. ZirMed was ... solution for large hospitals and medical centers over 200 beds ... Black Book,s healthcare technology user survey history. ...
Breaking Medicine Technology: