Navigation Links
Mouse Study Hints at New Path for Diabetes Treatment
Date:4/12/2012

By Serena Gordon
HealthDay Reporter

THURSDAY, April 12 (HealthDay News) -- A potential new treatment for type 2 diabetes targets the hormone glucagon instead of insulin, according to a new study in mice.

Although the research hasn't yet progressed past animal models of the disease, initial results suggest that the novel therapy can lower blood sugar, decrease insulin resistance, lower cholesterol and help keep fatty deposits from settling in the liver.

What's more, the researchers didn't see any adverse effects from the treatment.

"A new target for the adverse effects of glucagon on diabetes has been identified, and with treatment we got rid of all the bad stuff, but didn't cause side effects," said the study's lead author, Dr. Ira Tabas, a distinguished professor of medicine at Columbia University Medical Center, in New York City.

Results of the study are published in the April 12 online edition of Cell Metabolism.

Glucagon is a hormone whose main role is to protect the body and brain from low blood-sugar levels during periods of fasting, such as overnight. It is produced by the alpha cells in the pancreas, Tabas said. When the alpha cells in the pancreas sense dropping blood sugar and insulin levels, they secrete glucagon, which in turn, causes the liver to produce glucose to feed the brain and body.

Normally, glucagon only kicks in when you're starving, because it senses low insulin levels. But, in type 2 diabetes, the body becomes resistant to insulin, so even though insulin is present, the liver thinks the body has no glucose because the insulin isn't helping get glucose into the body's cells the way it should, Tabas explained. That causes the liver to send out a signal for glucagon, and then the liver releases more sugar. "It just turns into a horrible feedback cycle," he said.

Commenting on the study, Dr. Vivian Fonseca, president of medicine and science at the American
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

1

GOOD

Page: 1 2 3

Related medicine news :

1. Rapamycin rescues learning, memory in Alzheimers mouse model
2. NIA researchers find gene to explain mouse embryonic stem cell immortality
3. Dxtra Introduces New Solid Stainless Steel Mouse Pad
4. UCSF Transgenic Mouse Mimics Parkinson's Earliest Symptoms
5. McGill-UBC project creates mouse grimace scale to help identify pain in humans and animals
6. Fat in Males, Females Differs Genetically, Mouse Study Shows
7. Ergonomic HandShoe Mouse Publish Proof of Unique Difference with Competition
8. Rheumatoid arthritis signaling protein reverses Alzheimers disease in mouse model
9. Treatment for S. aureus skin infection works in mouse model
10. Mouse Study May Help Explain Fish Oils Benefits
11. Mouse Study Reveals a Cancer Cell Escape Route
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Mouse Study Hints at New Path for Diabetes Treatment
(Date:5/23/2013)... CA (PRWEB) May 23, 2013 ... outreach program being tackled by the Safe Passage Committee ... Fullpower personal safety workshop for women on ... teaches personal safety skills programs for people of all ... us their experiences with street harassment for years,” said ...
(Date:5/23/2013)... May 23, 2013 Dimensional Insight, ... solutions, announced today that Paul Comras, director ... speak at the 2013 International Medical Users Software ... Expense & Revenue Visibility from Your General Ledger.” ... 29 from 2:30-3:25 p.m. in Azalea 1 at ...
(Date:5/23/2013)... IN (PRWEB) May 23, 2013 ... Modernfold, a DORMA company, is pleased to announce ... vinyl coverings for its pacesetting space division products. ... products and wallcoverings, the new patterns and colors ... , Through meetings with a team of ...
(Date:5/23/2013)... members of the PETA International Science Consortium, Ltd., ... Safety Improvement Act of 2013: , Reform of ... also modernizes toxicity testing. , Ensuring the ... important goal. Reforming the EPA,s Toxic Substances ... the National Research Council,s vision for transforming toxicity ...
(Date:5/23/2013)... Bronson Gray HealthDay Reporter , , WEDNESDAY, May 22 ... device used to save an infant born with a serious ... marriage of bioengineering and surgery. A report in the ... the situation that sparked the innovation. At first, the ... began to have difficulty breathing and eating when he was ...
Breaking Medicine News(10 mins):Health News:San Francisco Tenderloin Women Say “No!” to Street Harassment: Safe Passage Sponsors Kidpower Adult Safety Skills Workshops and Resources 2Health News:San Francisco Tenderloin Women Say “No!” to Street Harassment: Safe Passage Sponsors Kidpower Adult Safety Skills Workshops and Resources 3Health News:San Francisco Tenderloin Women Say “No!” to Street Harassment: Safe Passage Sponsors Kidpower Adult Safety Skills Workshops and Resources 4Health News:Dimensional Insight to Demonstrate How Hospitals Can Use Business Intelligence within MEDITECH Environments at 2013 International MUSE Conference 2Health News:Modernfold Debuts New Colors and Patterns for Space Division Products 2Health News:Docs Use 3-D Printer to Create Lifesaving Airway Device for Infant 2Health News:Docs Use 3-D Printer to Create Lifesaving Airway Device for Infant 3
... User,s ... HealthVault Profile, ANN ... delivers a variety of integrated healthcare services,announced that it has ... consumers collect, store, and share,health information online. The UNIVAL application, ...
... clinical nutritionist and women,s health practitioner, has formulated ... protection for beautiful skin, a strong immune system, ... vision. Dr. Lark,s Thrive! is available exclusively ... Healthy Directions, LLC, one of the largest North ...
... Every year in Jacksonville,nearly 600 adults experience ... long road to recovery lacked long-term support. Today, ... only program,in Florida created to help people with ... reintegration., The Brain Injury Association of America ...
... MADISON, N.J., Oct. 22 Wyeth (NYSE: WYE ),announced ... Ann Stribling v. Wyeth,in New Jersey State Court in ... assessed total damages of $3 million. Wyeth is reviewing,its ... finding and believe it is,unsupported by the evidence, which ...
... Utilizing a new, innovative,twist on the popular Christmas toy ... Points by Sheraton Denver Southeast and give,back to the ... and the community may donate new costumes for the,Kunsberg ... Jewish,Medical and Research Center., "The Glendale Raptors are ...
... how cancer develops , , WEDNESDAY, Oct. 22 (HealthDay News) -- ... have grown entire prostates in mice. , This feat was ... stem cells from other types of cells, according to a ... , This information still has to be confirmed in humans, ...
Cached Medicine News:Health News:UNIVAL(R), Inc. Becomes a Microsoft(R) HealthVault(TM) Application Provider 2Health News:Susan Lark, MD Develops a Powerful ORAC Drink Packed with the Antioxidant Power of Nine Fruits 2Health News:Susan Lark, MD Develops a Powerful ORAC Drink Packed with the Antioxidant Power of Nine Fruits 3Health News:Susan Lark, MD Develops a Powerful ORAC Drink Packed with the Antioxidant Power of Nine Fruits 4Health News:Brooks Rehabilitation Opens First Work-Based Brain Injury Rehab Program in Florida 2Health News:Glendale Raptors Join Four Points by Sheraton Denver Southeast and Animal Planet's Dr. Kevin Fitzgerald for Second Annual Halloween Costume Drive & Halloween Party for Kunsberg School at National Jewish Medical and Research Center 2Health News:New Prostrates Grown From Single Stem Cell 2
(Date:5/23/2013)... , May 23, 2013 Israel Brain ... 2013 , Israel,s 1 st ... 14 th -15 th in Tel Aviv ... innovative city in the world by the Wall Street ... BrainTech Israel 2013 will showcase the latest breakthroughs in ...
(Date:5/23/2013)... 2013  Intercept Pharmaceuticals, Inc. (Nasdaq: ICPT ... the development and commercialization of novel bile acid therapeutics ... cirrhosis, today announced that Mark Pruzanski ... at the Deutsche Bank Securities 38th Annual Health Care ... May 29, 2013 at 4:10 p.m. ET. ...
(Date:5/23/2013)... May 23, 2013  MedVantx, Inc., the company that ... channel announced today the Company has completed a major ... in pharmaceutical products and the upgrade of its systems ... facilities in its specialty home delivery pharmacy in ... leading pharmaceutical manufacturers, physicians, health systems and payors novel ...
Breaking Medicine Technology:Israel Brain Technologies Announces Israel's 1st International Brain Technology Conference 2Israel Brain Technologies Announces Israel's 1st International Brain Technology Conference 3MedVantx Achieves Significant Milestone of Managing $1.5B in Prescription Medications and Completes Facilities Expansion While Upgrading To Offer Current Good Manufacturer Practices (cGMP)-level Quality Systems in their Home Delivery Pharmacy 2MedVantx Achieves Significant Milestone of Managing $1.5B in Prescription Medications and Completes Facilities Expansion While Upgrading To Offer Current Good Manufacturer Practices (cGMP)-level Quality Systems in their Home Delivery Pharmacy 3
Straight 8 mm downcutting Royce blade. Can be placed in closed handle for protection. Rigid handle when folded and locked. Straight 8 mm downcutting blades. Handle length folded 109 mm, 4.3 inches....
Duckbill. 3.5 mm tip. Light curve....
2 mm. Angled 13 degrees, 15 mm from angle to tip. Round handle....
2 mm curved tip. Round handle. Designated most popular model or size....
Medicine Products: