Navigation Links
Mouse Model of Age-Related Macular Degeneration Developed
Date:1/28/2008

Researchers say it will allow for testing of new drugs for vision-robbing disease

MONDAY, Jan. 28 (HealthDay News) -- The first animal model of age-related macular degeneration (AMD) has been developed by Cleveland Clinic researchers.

This mouse model will help improve knowledge about the development and progression of the disease and will enable pre-clinical testing of new drugs for AMD, a leading cause of blindness in the elderly.

The researchers created this animal model of AMD by modifying specific proteins found in mouse blood, forcing the immune system to mount a response that led to the development of the characteristics of AMD.

"More than 8 million Americans are living with vision loss caused by AMD, and 250,000 new cases are diagnosed each year," research team leader Joe G. Hollyfield, of Cleveland Clinic's Cole Eye Institute, said in a prepared statement.

"The discovery of the animal model of AMD presents a significant opportunity to efficiently and effectively develop and test novel therapies to both prevent the disease and slow vision loss. Research conducted today may one day help find a cure for this progressive disease," Hollyfield said.

The creation of the mouse AMD model is described in a report in the Jan. 27 online edition of Nature Medicine.

AMD is the most common cause of vision loss among American adults aged 60 and older. The disease gradually destroys sharp, central vision, which is needed for seeing objects clearly and for common daily tasks such as reading and driving.

More information

The U.S. National Eye Institute has more about age-related macular degeneration.



-- Robert Preidt



SOURCE: Cleveland Clinic, news release, Jan. 27, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Effectiveness of mouse breeds that mimic Alzheimers disease symptoms questioned
2. Mouse vision has a rhythm all its own
3. Mouse Study Gives Clues to Colitis
4. Mouse mammary tumor virus can replicate in human cells
5. A longer-living, healthier mouse that could hold clues to human aging
6. Gene Tweak Reverses Aging in Mouse Skin Cells
7. Chromatin remodeling complex connected to DNA damage control
8. Health care incentive model offers collaborative approach
9. Novel 3-D cell culture model shows selective tumour uptake of nanoparticles
10. 4-Star Gen. Barry McCaffrey, Former U.S. Drug Czar, to Address National Drug Crisis, Keynote Grand Opening of New Allenwood, PA National Model Detox Center
11. A classic method for modeling skin cancer is featured in Cold Spring Harbor Protocols
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Mouse Model of Age-Related Macular Degeneration Developed
(Date:2/20/2017)... ... February 20, 2017 , ... Sensogram Technologies ... by for a visit this week at HIMSS 2017 Conference & Exhibition. The ... the globe. Sensogram will be featured in the conference’s Connected Health Experience section, ...
(Date:2/20/2017)... Petersburg, Fla. (PRWEB) , ... February 20, 2017 , ... ... its research and education building. A topping out ceremony on Friday marked the halfway ... The building, set to open in Fall 2018, will serve as a center for ...
(Date:2/19/2017)... , ... February 19, 2017 , ... The Citadel’s new ... nursing students, is being led by Amelia Joseph, Ph.D. Joseph was engaged by the ... of the nursing department in early 2016. After a nation-wide search, she was selected ...
(Date:2/19/2017)... Boston,MA (PRWEB) , ... February 19, 2017 , ... ... software solutions for connected home healthcare, will join forces with Healthwise ® ... and education. Healthwise, the industry leader in evidence-based health education, technology and ...
(Date:2/18/2017)... Beverly Hills, California (PRWEB) , ... February 17, ... ... 273-3007, info@drvallecillos.com , drvallecillos.com , Beverly Hills plastic surgeon ... reduce subcutaneous fat cells. , Dr. Vallecillos says, "Traditionally, plastic surgery has been ...
Breaking Medicine News(10 mins):
(Date:2/17/2017)... February 17, 2017 According to a new ... Liquid Particle Counters), Application (Cleanroom Monitoring, Contamination Monitoring of Liquids), and ... published by MarketsandMarkets, the market is expected to reach USD 330.6 ... CAGR of 3.7% from 2016 to 2021. ... ...
(Date:2/17/2017)... -- Research and Markets has announced the addition of the ... their offering. ... separate comprehensive analytics for the US, Canada , ... , and Rest of World. Annual estimates and forecasts are provided ... provided for these markets. Market data and analytics are derived from primary ...
(Date:2/17/2017)... 2017   FormFast , the leader in electronic ... with Engage , one of the largest MEDITECH ... FormFast will serve as the forms automation and electronic ... MEDITECH .  FormFast is a MEDITECH ... and enhance the electronic health record. FormFast,s technology bridges ...
Breaking Medicine Technology: