Navigation Links
Mouse Model of Age-Related Macular Degeneration Developed

Researchers say it will allow for testing of new drugs for vision-robbing disease

MONDAY, Jan. 28 (HealthDay News) -- The first animal model of age-related macular degeneration (AMD) has been developed by Cleveland Clinic researchers.

This mouse model will help improve knowledge about the development and progression of the disease and will enable pre-clinical testing of new drugs for AMD, a leading cause of blindness in the elderly.

The researchers created this animal model of AMD by modifying specific proteins found in mouse blood, forcing the immune system to mount a response that led to the development of the characteristics of AMD.

"More than 8 million Americans are living with vision loss caused by AMD, and 250,000 new cases are diagnosed each year," research team leader Joe G. Hollyfield, of Cleveland Clinic's Cole Eye Institute, said in a prepared statement.

"The discovery of the animal model of AMD presents a significant opportunity to efficiently and effectively develop and test novel therapies to both prevent the disease and slow vision loss. Research conducted today may one day help find a cure for this progressive disease," Hollyfield said.

The creation of the mouse AMD model is described in a report in the Jan. 27 online edition of Nature Medicine.

AMD is the most common cause of vision loss among American adults aged 60 and older. The disease gradually destroys sharp, central vision, which is needed for seeing objects clearly and for common daily tasks such as reading and driving.

More information

The U.S. National Eye Institute has more about age-related macular degeneration.

-- Robert Preidt

SOURCE: Cleveland Clinic, news release, Jan. 27, 2008

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Effectiveness of mouse breeds that mimic Alzheimers disease symptoms questioned
2. Mouse vision has a rhythm all its own
3. Mouse Study Gives Clues to Colitis
4. Mouse mammary tumor virus can replicate in human cells
5. A longer-living, healthier mouse that could hold clues to human aging
6. Gene Tweak Reverses Aging in Mouse Skin Cells
7. Chromatin remodeling complex connected to DNA damage control
8. Health care incentive model offers collaborative approach
9. Novel 3-D cell culture model shows selective tumour uptake of nanoparticles
10. 4-Star Gen. Barry McCaffrey, Former U.S. Drug Czar, to Address National Drug Crisis, Keynote Grand Opening of New Allenwood, PA National Model Detox Center
11. A classic method for modeling skin cancer is featured in Cold Spring Harbor Protocols
Post Your Comments:
Related Image:
Mouse Model of Age-Related Macular Degeneration Developed
(Date:6/27/2016)... ... June 27, 2016 , ... "FCPX editors can now reveal ... Final Cut Pro X," said Christina Austin - CEO of Pixel Film Studios. ... Cut Pro X users can now reveal the media of their split screens ...
(Date:6/27/2016)... ... June 27, 2016 , ... ... strategic partnership with Connance, a healthcare industry leader providing predictive analytics to ... technology combine to provide health systems, hospitals and ambulatory surgical centers with ...
(Date:6/27/2016)... Park, KS (PRWEB) , ... June 27, 2016 , ... ... in retailers of Eyeglasses . , Millions of individuals in the United States ... eyeglasses have become a way to both correct vision and make a fashion statement. ...
(Date:6/26/2016)... Michigan (PRWEB) , ... June 26, 2016 , ... On ... as sponsor of the 2016 Cereal Festival and World’s Longest Breakfast Table in Battle ... honor of the city’s history as home to some of the world’s leading providers ...
(Date:6/26/2016)... North Carolina (PRWEB) , ... June 26, 2016 , ... ... release of a new product that was developed to enhance the health of felines. ... for centuries. , The two main herbs in the PawPaws Cat Kidney Support ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016  Consumers have taken ... regulators/payers have placed more emphasis on patient outcomes. ... support programs in the pharmaceutical industry have evolved ... Consequently, pharmaceutical companies are focusing on becoming more ... providing products and services that improve health. ...
(Date:6/24/2016)... , June 24, 2016 ... Markets has announced the addition of the " ... offering. This ... and provides an updated review, including its applications in ... the total market, which includes three main industries: pharmaceutical ...
(Date:6/24/2016)... , June 24, 2016  American Respiratory Labs (ARL), a ... now able to perform sophisticated lung assessments in patients, homes, thanks ... Inc. Patients are no longer limited to having ... PRO ® , ARL patients like Jeanne R. of ... the comfort of her own home. ...
Breaking Medicine Technology: