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Mount Sinai researchers discover origin of immune cells in the brain
Date:10/22/2010

all cells that develop from the fluorescent precursors should remain fluorescent. The researchers activated the fluorescence as early as seven days after conception. When they examined adult mice they found fluorescent microglia but no fluorescent macrophages. These results established that microglia are unique in that they originate from precursors that arise around seven days after conception.

"Moving forward we need to further study the normal development of precursor blood cells into microglia, which should help identify the role of microglia in various brain diseases and ultimately lead to advances in treatments," said Dr. Merad.


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