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Mount Sinai recognized as Center of Excellence for Research in Alzheimer's disease
Date:10/10/2007

Mount Sinai School of Medicine has just received a major grant from the National Center for Complementary and Alternative Medicine (NCCAM), a component of the National Institutes of Health (NIH) and lead Federal agency for research on complementary and alternative medicine. This new grant creates a Center of Excellence for Research in Complementary and Alternative Medicine at Mount Sinai that will focus on Alzheimers disease. The new Center has been awarded an estimated $8 million grant over the next five years to continue its research and study of "age defying diets." There will be an emphasis on grape-derived compounds that may be able to delay or possibly prevent the onset of Alzheimers disease .

The new Center will systematically explore, through basic and preclinical research, the idea that a longer, disease-free life isn't necessarily only in our genes but also partly in our hands depending upon our lifestyles, said principal investigator of the new Centers research- Dr. Giulio Maria Pasinetti, M.D., Ph.D. Professor of Psychiatry and Neuroscience, Geriatrics and Adult Development & Director of Neuroinflammation Research Center in Department of Psychiatry at Mount Sinai School of Medicine.

Protective roles of dietary grape-derived compounds in Alzheimers disease will be the focus of new research at the Center at Mount Sinai. Preclinical studies will be conducted to identify natural compounds extracted from grapes, known as polyphenols that might have a protective role in Alzheimers disease. Using mice genetically modified to develop Alzheimers disease-type neuropathology and memory loss, researchers led by Dr. Pasinetti will investigate the biological mechanisms by which these grape-derived compounds may affect changes in the brain that are characteristic of Alzheimers disease and associated with cognitive decline.

NCCAM has just added three new Centers of Excellence for Research on Complementary and Alternative Medicine (CAM)
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Contact: Mount Sinai Newsroom
newsmedia@mssm.edu
212-241-9200
The Mount Sinai Hospital / Mount Sinai School of Medicine
Source:Eurekalert

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