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Mount Sinai presents treatment trends, vaccine research, prognosis data at ASCO
Date:5/17/2012

or mRCC, leaving clinicians uncertain of the role of CyNx.

A research team, led by Che-kai Tsao, MD, Chief Fellow, Hematology and Medical Oncology at Mount Sinai School of Medicine, analyzed a database of 2,780 patients with mRCC between 2001 and 2008 to determine patterns of CyNx use. Between 2001 and 2005, half of patients had CyNx, but in 2008, that number decreased to 38 percent. In addition, black or hispanic ethnicity, older age, male gender, and larger tumor size were associated with a decrease in the use of CyNx.

"Use of cytoreductive nephrectomy decreased after VEGFR tyrosine kinase inhibitors were approved, and potential demographic differences in its use may be a focus of future research," said Dr. Tsao. "Our research underscores the need for definitive data on the role of cytoreductive nephrectomy today, and results of ongoing randomized trials are needed to refine the role of this treatment modality."


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