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Mount Sinai presents important findings at the 2014 American Urological Association Meeting
Date:5/17/2014

PSA, a significant improvement in survival was noted for patients who generated antibodies against this antigen.

"The study data demonstrated that a subset of patients (30%) vaccinated against one specific antigen, PAP, develop immune response to other antigens; this antigen spread is associated with a profound enhancement of survival. This study thus demonstrates some of the complexities of immunotherapy in patients and serves as a backdrop for further studies to enhance anticancer immune therapies," said Dr. Hall.

This multi-center study included collaboration with Johns Hopkins University School of Medicine, Baltimore, MD; Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA; University of California, San Francisco, CA; Indiana University Simon Cancer Center, Indianapolis, IN; and University of Washington School of Medicine, Seattle, WA. Grant funding for this study was provided by the Dendreon Corporation, Seattle, WA.

  • Stimulated Intrauterine Insemination Live Birth Rates are Adversely Affected by Increasing Paternal Age

It is well established that increasing maternal age leads to a higher risk of infertility, miscarriage, and chromosomal defects in offspring. A research team at Icahn School of Medicine at Mount Sinai, led by Natan Bar-Chama, MD, Associate Professor, Urology and Obstetrics, Gynecology and Reproductive Science, Icahn School of Medicine at Mount Sinai sought to answer whether paternal age had a negative impact on the ability to reproduce and the rate of successful outcomes using stimulated intrauterine insemination (IUI). In the largest study of its kind, researchers retrospectively reviewed 18,806 IUI cycles from a single center from 2003-2011. Success rates were defined as live births rates. The mean maternal age in the cohort was 36.4 years and the mean paternal age was 38.4 years. The cumulative live birth rate was 23%. After adjusting for standard predictors of life birt
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Contact: Lucia Lee
newsmedia@mssm.edu
212-241-9200
The Mount Sinai Hospital / Mount Sinai School of Medicine
Source:Eurekalert

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