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Mount Sinai presents important findings at the 2014 American Urological Association Meeting
Date:5/17/2014

(NEW YORK EMBARGO May 17, 2014) Researchers at the Icahn School of Medicine at Mount Sinai will present several landmark studies at the 2014 American Urological Association (AUA) annual meeting May 17-19, 2014 in Orlando, FL, including data on an immune response in prostate cancer tumors, effects of paternal age on stimulated insemination live birth rates, issues of sexual function after cystectomy and a comparison of modalities for the treatment of benign prostatic hyperplasia (BPH).

Meeting attendees will be able to view a live 3-dimensional video feed of a robotic prostatectomy performed by Ashutosh K. Tewari, MBBS, MCh, Chairman, Milton and Carroll Petrie Department of Urology, Icahn School of Medicine at Mount Sinai, who has performed over 5,500 robotic prostatectomies and is one of the world's foremost researchers and surgeons in this field.

Highlights of Mount Sinai research at AUA:

  • Sipuleucel-T-Induced Antigen Spread: Immune Response to Prostate-Specific Antigen Correlates with Improved Overall Survival Rates

Sipuleucel-T is an autologous cellular immunotherapy indicated for the treatment of asymptomatic metastatic castration resistant prostate cancer by inducing an immune response against prostatic acid phosphotase (PAP). Researchers including Simon J Hall, MD, Director of the Barbara and Maurice Deane Prostate Health and Research Center, Associate Professor, Urology, Icahn School of Medicine at Mount Sinai, sought to determine whether this treatment induced an immune response to other potential prostate cancer antigens such as PSA after treatment with sipuleucel-T and if this response was associated with enhanced overall survival. A total of 512 men were evaluated with 341 receiving sipuleucel-T and 171 in the control group. A subset of men treated with sipuleucel-T generated immune responses to several known prostate cancer antigens including PSA, PSMA and human kallikrien-2. In the case of
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Contact: Lucia Lee
newsmedia@mssm.edu
212-241-9200
The Mount Sinai Hospital / Mount Sinai School of Medicine
Source:Eurekalert

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