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Mount Sinai and the Atlantic Host Working Summit on Big Data in New York City
Date:10/29/2013

e that has helped Mount Sinai scientists publish more than 25 research papers in the last year-and-a-half. Minerva is used for numerous initiatives across the institution. Examples include storing information from Mount Sinai's biobank, or BioME, a collection of DNA and plasma samples from more than 27,500 individuals, and then analyzing them for specific diseases, and sequencing thousands of individuals with autism spectrum disorder for the multinational Autism Sequencing Consortium.

Under the leadership of Eric Schadt, PhD, Director of the Icahn Institute of Genomics and Multiscale Biology, Mount Sinai has recruited top data scientists from Stanford University, IBM Corp., and other leading institutions to form a new epicenter for personalized medicine that will lead to better treatments for patients. Through the use of sophisticated clustering algorithms, Dr. Schadt, also Chair of Genetics and Genomic Sciences, and the Jean C. and James W. Crystal Professor of Genomics, says Minerva analyzes and categorizes patients so they can receive personalized treatments. "Once you've grouped the patients, then you can see how they were diagnosed, how they were treated, and whether the treatment worked," he said.

Many of the summit's participants acknowledged the steep learning curve, significant financial investment, and challenges involved in sharing data with other institutions.

"Not all data is good data, and not all data is standardized. Sometimes the problem is how well you asked the patient a question, or how well the answer was coded," said David Artz, MD, Chief Medical Information Officer at Memorial Sloan-Kettering Cancer Center. "Sometimes we can't get apples to apples comparisons across cancer centers."

Jim Peters, Founder and Chief Executive Officer of MedMining, a Geisinger Health System unit which licenses HIPAA-compliant, de-identified EHR data extracts to promote health resea
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