Navigation Links
Mount Sinai Researchers Identify Gene Mutations in Congenital Heart Disease
Date:5/12/2013

New York, NY (PRWEB) May 12, 2013

Mutations in eight genes have been linked to severe forms of congenital heart disease (CHD), according to a study involving investigators at the Icahn School of Medicine at Mount Sinai.
The study used an advanced technique known as high-throughput sequencing that enables scientists to obtain the sequence of all 22,000 human genes and the entire human genome at one time. Results from the study are published online today in the journal Nature.

The research was conducted through the National Heart, Lung, and Blood Institute (NHLBI)-supported Pediatric Cardiac Genomics Consortium, an international, multi-center collaborative effort. The NHLBI is part of the National Institutes of Health (NIH).

“The eight genes that we identified are important in chromatin remodeling,” said a study coinvestigator, Bruce D. Gelb, MD, Director of The Mindich Child Health and Development Institute (MCHDI) at the Icahn School of Medicine at Mount Sinai.

Chromatin remodeling controls which genes work in which cells. For example, chromatin remodeling makes sure that only genes that control the heart are used in the heart, and genes that are used in the brain are turned on and off in the brain. When chromatin remodeling genes are altered, the on/off status of many genes is altered.

“Together, all of the gene mutations we found account for about 10 percent of the severe congenital heart disease,” said Dr. Gelb. “We may eventually be able to offer better early interventions that slow the natural history of congenital heart disease.”

Congenital heart disease affects approximately 8 in 1,000 newborns. It encompasses a wide variety of defects. Some forms of CHD c
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2

Related medicine news :

1. Icahn School of Medicine at Mount Sinai Honors Innovators in Scientific Research and Health Care Philanthropy at 2013 Commencement Ceremony
2. The Mount Sinai Medical Center Adopts HIPAA-Compliant Mobile Care App Across the Enterprise
3. Mother’s Mountain Sponsors 31st Annual Sugarloaf Marathon
4. Maria Mountain Announces “The Hockey Workout Club”
5. Appliance Repair Huntsville AL "Best of the Best" Awarded to Mr. Appliance Over the Mountain for Excellence by Follow Media Consulting, Inc.
6. Stryker Hip Recall Lawsuits Stemming from Rejuvenate and ABG II Hip Stem Recall Continue to Mount in New Jersey Litigation
7. Jinwill lighting Releases LED Flood Light with Magnetic Mount Pedestal Base
8. GranuFlo Lawsuits Filed in Wake of GranuFlo and NaturaLyte Recall Mount in State and Federal Courts, Bernstein Liebhard LLP Reports
9. Mountain Climbers Bodyweight Ab Exercise Demonstrated in New Video from Bodyweight Torch
10. Appliance Repair Birmingham AL "Best of the Best" Awarded to Mr. Appliance Over the Mountain for Excellence by Follow Media Consulting, Inc.
11. Paramount Direct Marketing Announces They Will Be Attending the Integrated Marketing Week Conference.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/5/2015)... ... July 05, 2015 , ... Doctors at the Swedish Cancer ... combination may one day change the outlook for people with pleural mesothelioma. Surviving Mesothelioma ... , Researchers report that five mesothelioma patients treated with 25Gy of radiation over ...
(Date:7/4/2015)... New York, NY (PRWEB) , ... July 04, 2015 , ... ... suggest that 15% of chronic pain sufferers have pain located in the neck. Another ... referred from the neck. Chiropractic literature suggests that 45% of American workers ...
(Date:7/3/2015)... ... July 04, 2015 , ... The Harvest Hope Food Bank will hopefully be ... AlignLife offices in the area of Greenville SC are making it their mission ... by patients only. They are asking for donations from the public as well. As part ...
(Date:7/3/2015)... , ... July 03, 2015 ... ... the sessions and speaker lineup for its 2015 Annual Conference , ... August 6-8, 2015 at the Renaissance Orlando at SeaWorld in Orlando, Florida. ...
(Date:7/3/2015)... ... July 03, 2015 , ... B. ... has been retained to lead a national president recruitment for Regional ... the healthcare industry, B. E. Smith has recently placed more than 1,000 healthcare ...
Breaking Medicine News(10 mins):Health News:New Mesothelioma Study Calls IMRT/Surgery Combo “Innovative and Promising”, According to Surviving Mesothelioma 2Health News:New Advancement in Treatment of Chronic Neck Pain 2Health News:New Advancement in Treatment of Chronic Neck Pain 3Health News:Greenville Area AlignLife Offices to do a Thanksgiving in July Food Drive 2Health News:Greenville Area AlignLife Offices to do a Thanksgiving in July Food Drive 3Health News:RNS Announces Sessions and Speaker Lineup for the 2015 Annual Conference of the Rheumatology Nurses Society 2Health News:RNS Announces Sessions and Speaker Lineup for the 2015 Annual Conference of the Rheumatology Nurses Society 3Health News:Regional Care, Inc. Retains B. E. Smith to Recruit New President 2Health News:Regional Care, Inc. Retains B. E. Smith to Recruit New President 3
... Dec. 8 BHR Pharma, LLC (BHR) ... application with the U.S. Food and Drug Administration (FDA) for its ... year, the company made public plans to initiate a global, Phase ... the safety and effectiveness of BHR-100 as a neuroprotective agent for ...
... , CINCINNATI and JACKSONVILLE, Fla., Dec. 8 LCA-Vision ... correction services under the Lasik Plus ® brand, announced today that ... free Lasik Plus® corrective vision surgery to U.S. military veterans ... Warrior Project, and is doing its part to enhance the lives ...
... , SAN DIEGO, Dec. 8 PROVERI, Inc. ... a winner of the annual New England Venture Summit Top Innovator ... recognizes those that play a leading role in innovation for the ... winners, Waldemar Lernhardt, Ph.D., President and Chief Executive Officer of PROVERI, ...
... , ANN ARBOR, Mich., Dec. 8 ... bench-top flow cytometer systems, today announced the 2009 recipients of ... free Accuri C6 Flow Cytometer® System each year to two ... Europe, who propose innovative uses of flow cytometry. Explicitly ...
... , LONDON, ... both structural reform and unavailability of resources as the region,s working ... This calls for the introduction of new schemes in healthcare that ... ageing population. The involvement of Information and Communication Technology (ICT) in ...
... ... UK’s premier centre for Integrated Medicine, launches Regenerus, the most comprehensive anti-ageing assessment and ... ... Secretary, Andy Burnham, published the results of a Department of Health Survey that reveals ...
Cached Medicine News:Health News:BHR Pharma Files Investigational New Drug Application, Receives Orphan Drug Designation, for Traumatic Brain Injury Treatment 2Health News:LCA-Vision Joins Forces With the Wounded Warrior Project to Give the Gift of Enhanced Vision to Wounded American Heroes 2Health News:PROVERI, Inc. Named a Top Innovator Winner 2Health News:Innovative Applications of Flow Cytometry Win U.S. and European Researchers Free Accuri C6 Flow Cytometer(R) Systems 2Health News:Innovative Applications of Flow Cytometry Win U.S. and European Researchers Free Accuri C6 Flow Cytometer(R) Systems 3Health News:Innovative Applications of Flow Cytometry Win U.S. and European Researchers Free Accuri C6 Flow Cytometer(R) Systems 4Health News:Frost & Sullivan: E-Healthcare in Western Europe Presents a Significant Market Opportunity for Wireless Technologies 2Health News:Frost & Sullivan: E-Healthcare in Western Europe Presents a Significant Market Opportunity for Wireless Technologies 3Health News:Regenerus Life Enhancement Programme from The Diagnostic Clinic Will Take the Fear Out of Ageing 2Health News:Regenerus Life Enhancement Programme from The Diagnostic Clinic Will Take the Fear Out of Ageing 3Health News:Regenerus Life Enhancement Programme from The Diagnostic Clinic Will Take the Fear Out of Ageing 4Health News:Regenerus Life Enhancement Programme from The Diagnostic Clinic Will Take the Fear Out of Ageing 5Health News:Regenerus Life Enhancement Programme from The Diagnostic Clinic Will Take the Fear Out of Ageing 6
(Date:7/3/2015)... July 4, 2015 A global ... hypertension, diabetes and thyroid disorders in Central and ... platforms and a major conference dedicated to these diseases. ... Manage Diabetes Online , Manage Hypertension Online ... and operated by EXCEMED - combine the ...
(Date:7/3/2015)... -- Obsidian HDS, the developer of PharmaShine ( www.pharmashine.com ... of data on pharmaceutical and device industry payments to ... 2014 Open Payments General and Research data released by ... data disclosed on Open Payments for 2014 includes information ... $6.49 billion and is the largest public disclosure of ...
(Date:7/2/2015)... , July 2, 2015 /PRNewswire/ - ESSA Pharma Inc. ("ESSA" ... shares have been approved for listing and trading on the ... ESSA will begin trading on NASDAQ on July 9, 2015.  ... Exchange under the symbol "EPI". As a result ... each of the Company,s outstanding special warrants issued on January ...
Breaking Medicine Technology:Combating Three Major Chronic Diseases in Central and South-East Asia With Medical Education 2New Open Payments (Sunshine Act) Data Now Searchable on PharmaShine 2ESSA Pharma Inc. to Commence Trading on the NASDAQ Capital Market 2ESSA Pharma Inc. to Commence Trading on the NASDAQ Capital Market 3ESSA Pharma Inc. to Commence Trading on the NASDAQ Capital Market 4
... 2011 /PRNewswire-Asia-FirstCall/ -- Dehaier Medical Systems ... emerging leader in the development, assembly, marketing and sale ... today announced that it was granted three new patents ... of China ("SIPO"). The patent awards were related to ...
... Cellular Dynamics International (CDI) today announced the online publication ... demonstrating for the first time a methodology for researchers ... blood samples through the creation of induced pluripotent stem ... B-cell lines reprogrammed to EBV-free induced pluripotent stem cells," ...
Cached Medicine Technology:Dehaier Strengthens Intellectual Property Portfolio 2Dehaier Strengthens Intellectual Property Portfolio 3Cellular Dynamics International Unlocks the Potential of Banked Blood Samples 2
... A quality mini c-arm ... features a selective 6" ... view. XiScan mini c-arms ... intra-operative imaging systems used ...
The KM-500's unique viewing and alignment window lets you observe the targeted eye from any distance. Two rechargeable batteries provide continuous uninterrupted use. Each battery provides 60 minutes...
... freezing and quick defrosting by ... - cleans the probes for ... tips have high conductivity silver. ... Glaucoma and Intra-vitreal surgery. Includes ...
Khosla Precision and Quality in Medical and Surgical Products....
Medicine Products: