Navigation Links
Mount Sinai Researchers Identify Gene Mutations in Congenital Heart Disease
Date:5/12/2013

New York, NY (PRWEB) May 12, 2013

Mutations in eight genes have been linked to severe forms of congenital heart disease (CHD), according to a study involving investigators at the Icahn School of Medicine at Mount Sinai.
The study used an advanced technique known as high-throughput sequencing that enables scientists to obtain the sequence of all 22,000 human genes and the entire human genome at one time. Results from the study are published online today in the journal Nature.

The research was conducted through the National Heart, Lung, and Blood Institute (NHLBI)-supported Pediatric Cardiac Genomics Consortium, an international, multi-center collaborative effort. The NHLBI is part of the National Institutes of Health (NIH).

“The eight genes that we identified are important in chromatin remodeling,” said a study coinvestigator, Bruce D. Gelb, MD, Director of The Mindich Child Health and Development Institute (MCHDI) at the Icahn School of Medicine at Mount Sinai.

Chromatin remodeling controls which genes work in which cells. For example, chromatin remodeling makes sure that only genes that control the heart are used in the heart, and genes that are used in the brain are turned on and off in the brain. When chromatin remodeling genes are altered, the on/off status of many genes is altered.

“Together, all of the gene mutations we found account for about 10 percent of the severe congenital heart disease,” said Dr. Gelb. “We may eventually be able to offer better early interventions that slow the natural history of congenital heart disease.”

Congenital heart disease affects approximately 8 in 1,000 newborns. It encompasses a wide variety of defects. Some forms of CHD c
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2

Related medicine news :

1. Icahn School of Medicine at Mount Sinai Honors Innovators in Scientific Research and Health Care Philanthropy at 2013 Commencement Ceremony
2. The Mount Sinai Medical Center Adopts HIPAA-Compliant Mobile Care App Across the Enterprise
3. Mother’s Mountain Sponsors 31st Annual Sugarloaf Marathon
4. Maria Mountain Announces “The Hockey Workout Club”
5. Appliance Repair Huntsville AL "Best of the Best" Awarded to Mr. Appliance Over the Mountain for Excellence by Follow Media Consulting, Inc.
6. Stryker Hip Recall Lawsuits Stemming from Rejuvenate and ABG II Hip Stem Recall Continue to Mount in New Jersey Litigation
7. Jinwill lighting Releases LED Flood Light with Magnetic Mount Pedestal Base
8. GranuFlo Lawsuits Filed in Wake of GranuFlo and NaturaLyte Recall Mount in State and Federal Courts, Bernstein Liebhard LLP Reports
9. Mountain Climbers Bodyweight Ab Exercise Demonstrated in New Video from Bodyweight Torch
10. Appliance Repair Birmingham AL "Best of the Best" Awarded to Mr. Appliance Over the Mountain for Excellence by Follow Media Consulting, Inc.
11. Paramount Direct Marketing Announces They Will Be Attending the Integrated Marketing Week Conference.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/22/2014)... Lexington, Kentucky (PRWEB) October 22, 2014 ... an agreement that will change the current location of ... Road to South Limestone across from the University of ... be a state-of-the-art ambulatory care center, owned and operated ... meet the orthopaedic needs of children and their families ...
(Date:10/22/2014)... Los Angeles, California (PRWEB) October 22, 2014 ... Recovery 2.0: Move Beyond Addiction and Upgrade Your Life (Paperback; ... the field of Yoga & Recovery. This book is ... and thrive in a life of recovery. , Recovery ... of the 12 Steps; Recovery 2.0 is a guide for ...
(Date:10/22/2014)... 2014 During the Western United States’ ... runs dangerously low, Southern Oregon’s water is proving resistant ... the lowest mountain snow pack on record in 2014, ... early autumn.* That was the observation of journalist-hikers Art ... “Hiking Southern Oregon,” during an interview with water advocate ...
(Date:10/22/2014)... 2014 Healthcare professionals who are ... education at home or on-the-go via laptops, tablets ... brand new, premium Seminar-on-Demand CE courses. The new ... 2,000 hours of CE course offerings, ... experience. With such a diverse library, there’s something ...
(Date:10/22/2014)... 22, 2014 Although there are only 24 hours ... many people who have trouble finding time within their busy schedules ... for long periods of time to get in shape. Here are ... on the go. , Change Up Your Commute , Consider ... to add some exercise into your daily routine. If you must ...
Breaking Medicine News(10 mins):Health News:Shriners Hospitals for Children - Lexington Announces Plan to Build New $47 Million Facility 2Health News:Shriners Hospitals for Children - Lexington Announces Plan to Build New $47 Million Facility 3Health News:Hay House Announces The Official Release of Recovery 2.0: Move Beyond Addiction and Upgrade Your Life 2Health News:Hay House Announces The Official Release of Recovery 2.0: Move Beyond Addiction and Upgrade Your Life 3Health News:Southern Oregon Is West’s Most Drought Proof Fresh Water Region Say Hiking Guide Authors 2Health News:Southern Oregon Is West’s Most Drought Proof Fresh Water Region Say Hiking Guide Authors 3Health News:Southern Oregon Is West’s Most Drought Proof Fresh Water Region Say Hiking Guide Authors 4Health News:Top Provider of Continuing Education at Home Releases 20 New Online Courses 2Health News:HealthGuideMD Presents Ways to Improve Your Exercise and Fitness 2
... behind her dramatic weight loss over the past few months, and ... ,Jolie told reporters at the New York premiere ... lost weight is because shes not only still grieving over the ... in January, but also busy running around four young kids. ...
... some extra sleep before a big game could improve ... Cheri Mah and colleagues at Stanford University observed six ... were told to maintain their usual sleeping habits for ... were instructed to get as much extra sleep as ...
... study has found that obesity, high blood pressure, high cholesterol, ... age group of 18 24. , The ... Lofgren, Joanne Burke, Ruth Reilly and Jesse Morrell, at the ... study, researchers collected data from more than 800 undergraduates enrolled ...
... Salk Institute for Biological Studies have found in a study ... in everyday life, may contribute to the accumulation of ... Alzheimers disease. ,The researchers say that while aging ... number of studies have pointed to stress as a contributing ...
... are affected by scorching temperatures . ,Dogs in Jaipur ... canines being treated at veterinary hospitals everyday. ,Veterinarians ... don't have any sweat glands to keep cool. The sick ... treatments to bring their body temperature to normal. ...
... could save her so much time and money. But after a ... Africa's largest slum, she realized it could. ,With ... that uses human waste to produce gas to burn to heat ... ,"At first I thought it was a very strange idea - ...
Cached Medicine News:Health News:Emotional Stress Could Be a Factor in Causing Alzheimers: Study 2Health News:Bio-latrine Cleans Up Kenyan Slum and the Environment 2Health News:Bio-latrine Cleans Up Kenyan Slum and the Environment 3
(Date:10/20/2014)... -- Indianapolis interventional medical device maker NICO Corporation ... visualization leader Synaptive Medical announced today ... that they have joined forces to integrate their ... the first of its kind and will make ... BrainPath® interventional access technology and Synaptive,s BrightMatter™ real-time ...
(Date:10/20/2014)...  ResMed (NYSE: RMD ) today ... program, a comprehensive suite of software and service ... health care providers. ResMed Data ... information. It integrates valuable sleep and respiratory treatment ... platforms with customers, in-house or third-party electronic health ...
(Date:10/20/2014)... BioNano Genomics announced today achievement of a major milestone ... at 30X depth, sufficient for a genome map, in 24 ... and demonstrated for the IrysChip TM V2, the high-throughput ... will be rolled out to BioNano,s collaborators and customers over ... at the American Society for Human Genetics (ASHG) 2014 ...
Breaking Medicine Technology:Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 2Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 3Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 4Indianapolis' NICO Corporation and Toronto's Synaptive Medical, Inc. Announce First-Ever Intervention-Visualization Partnership with Goal to Improve Standard of Care in Neurosurgery 5ResMed Launches ResMed Data Exchange 2BioNano Genomics Announces One Human : One Chip : One Day 2BioNano Genomics Announces One Human : One Chip : One Day 3
... (NYSE: AZN ) announced today that the ... complete response letter (CRL) for the New Drug Application ... In the CRL, the FDA requested additional ... request that additional studies, including clinical studies, be conducted ...
... 2010 Insmed Incorporated (Nasdaq CM: INSM), a biopharmaceutical company, ... 16, 2010, from The NASDAQ Stock Market, notifying Insmed that ... until June 13, 2011, to regain compliance with the $1.00 ... The NASDAQ Capital Market, as set forth in NASDAQ Listing ...
Cached Medicine Technology:AstraZeneca Receives Complete Response Letter From US FDA For BRILINTA™ (Ticagrelor Tablets) 2NASDAQ Grants Insmed Incorporated 180-Day Extension to Regain Compliance with Minimum Bid Price Rule 2
Binocular indirect ophthalmic lenses. General diagnosis & treatment....
... Volk's super ... biomicroscopy lenses. Examination ... Provide unprecedented fundus ... addressing maximum potential ...
... series slit lamp biomicroscopy ... of the posterior pole. ... capability, specifically addressing maximum ... fundus image resolution & ...
Volk indirect lenses. High magnification views of the posterior pole....
Medicine Products: