Navigation Links
Mothers Less Likely to Pursue HPV Vaccination for Youngest Daughters
Date:4/30/2008

Mothers' Intentions Run Counter to CDC Recommendations

CINCINNATI, April 30 /PRNewswire/ -- Because the first national study of its kind has found that U.S. mothers report they are less likely to vaccinate daughters under age 13 against human papillomavirus virus (HPV), even though the vaccine is recommended for girls at age 11 and 12, it's incumbent upon the healthcare community to work to improve moms' acceptance of the vaccination for younger daughters, say researchers at Cincinnati Children's Hospital Medical Center who conducted the study. HPV is a sexually transmitted virus known to cause cervical cancer.

The study will be presented May 4 at the American Academy of Pediatrics Presidential Plenary session, of the annual meeting of the Pediatric Academic Societies in Honolulu.

"Because HPV is the most common sexually transmitted infection (see background information below) and often acquired soon after the onset of sexual activity, the CDC recommends that HPV vaccination ideally occur before a girl becomes sexually active, as the vaccine will not reverse HPV infection," says Jessica Kahn, M.D., a physician in the division of adolescent medicine at Cincinnati Children's and the study's lead author. Currently the U.S. Centers for Disease Control and Prevention (CDC) recommends that 11- and 12-year-old girls be targeted for HPV immunization. But the researchers found that mothers surveyed are currently not inclined to follow that guideline.

In the study, while 86 percent of moms intended to vaccinate a 16- to 18-year-old daughter, and 68 percent intended to vaccinate a 13- to 15-year-old daughter, fewer than half -- only 48 percent -- intended to vaccinate a 9- to 12-year-old daughter, according to the data analyzed by Dr. Kahn and her colleagues. "Mothers' intention to vaccinate against HPV is lowest for the younger daughters. Yet, younger girls are more likely than older girls to benefit from vaccination, which is why the CDC recommends that they be targeted for vaccination. This discrepancy between mothers' attitudes and CDC recommendations represents a challenge for health care providers."

"We found that mothers' beliefs about HPV vaccination are the most powerful determinants of whether they intend to vaccinate their daughters at this age. The findings of our study, in combination with results of the evolving literature on HPV vaccine acceptability, provide information that can be used to improve moms' acceptance of HPV vaccination for their younger daughters."

Factors independently associated with intention to vaccinate a younger daughter included belief that one's daughter should get a regular Pap screen and beliefs about HPV vaccines. The seven-item scale measuring beliefs about HPV vaccines included perceived benefits to HPV vaccination (such as whether that vaccination will protect one's daughter against cervical cancer), perceived barriers to vaccination (such as whether that vaccination may lead to riskier sexual behaviors), belief that the daughter is at risk for HPV infection, belief that HPV-related diseases such as cervical cancer are serious, and belief that one's doctor would recommend vaccination.

Dr. Kahn said that the most powerful individual predictors that were most associated with likelihood to vaccinate their younger daughters were (in order): belief that HPV vaccination would provide protection against cervical cancer, belief that vaccinated girls would not practice riskier sex, belief that one's daughter's clinician would recommend HPV vaccines for her, and belief that one's daughter is at risk for HPV infection.

"Because we found moms' personal beliefs play such an important role in their decisions to have younger daughters immunized against HPV, the development of evidence-based messages that emphasize adolescent girls' risk for HPV infection, the effectiveness of the vaccine in preventing cervical cancer, and clinician endorsement of vaccination may increase the acceptability of the HPV vaccine among parents and help to maximize HPV vaccine uptake," says Dr. Kahn. "A comprehensive approach to enhancing parental acceptability of HPV vaccination would involve the combined efforts of clinicians, health educators, advocacy groups, and public health personnel."

For the study, Dr. Kahn and her colleagues surveyed 10,521 mothers of adolescents enrolled in the Growing Up Today Study (GUTS), a longitudinal study of the children of mothers participating in the Nurses Health Study II (NHS 2), between June 2006 and February 2007. The survey assessed demographic factors, gynecologic history, communication with daughters about Pap screening, and mothers' beliefs about Pap testing and about HPV vaccines as well as intention to vaccinate daughters of varying ages. Researchers also looked at mothers' intention to get the vaccine themselves and found that 48 percent intend to be vaccinated.

Dr. Kahn's study was funded by the American Cancer Society and included researchers from Indiana University, the University of Texas Medical Branch Galveston and Harvard University Medical School. The senior author was Lindsay Frazier, M.D., Children's Hospital Boston.

The PAS meeting is the largest international meeting focused on research in child health. It is sponsored by the American Academy of Pediatrics, the American Pediatric Society, the Society for Pediatric Research, and the Ambulatory Pediatric Association.

BACKGROUND ON HPV: An estimated 6.2 million people 14 to 44 years old are newly infected with HPV each year in the United States, and of these infections, 74 percent occur among those 15 to 24 years old, according to the CDC. Infection with one of the more than 100 types of HPV usually causes no symptoms and resolves on its own, but a proportion of women infected with specific cancer-associated types may develop cervical cancer. Two of these types, 16 and 18, cause about 70 percent of cervical cancers in women. Two other types, 6 and 11, cause about 90 percent of genital warts. The CDC estimates that 11,100 new cervical cancer cases were diagnosed in 2007 and approximately 3,700 women died from cervical cancer in the U.S. Health care professionals use the Pap test to screen for cervical cancer.

In June 2006, the U.S. Food and Drug Administration approved a vaccine against four types of HPV, 6, 11, 16 and 18, based on data from clinical trials indicating that the vaccine was highly effective in preventing persistent infection with these strains and subsequent cervical cancer precursor lesions, vaginal and vulvar cancer precursor lesions and genital warts. The FDA approved the HPV vaccine for use in U.S. women aged 9 to 26 years.

Cincinnati Children's Hospital Medical Center, one of the leading pediatric research institutions in the nation, is dedicated to changing the outcome for children throughout the world. Cincinnati Children's ranks second among all pediatric institutions in the United States in grants from the National Institutes of Health. It has an established tradition of research excellence, with discoveries including the Sabin oral polio vaccine, the surfactant preparation that saves the lives of thousands of premature infants each year, and a rotavirus vaccine that saves the lives of hundreds of thousands of infants around the world each year. Current strategic directions include the translation of basic laboratory research into the development of novel therapeutics for the treatment of disease, and furthering the development of personalized and predictive medicine. Additional information can be found at http://www.cincinnatichildrens.org.


'/>"/>
SOURCE Cincinnati Children's Hospital Medical Center
Copyright©2008 PR Newswire.
All rights reserved

Related medicine news :

1. Fetal Cells Detected in Mothers Blood Years After Donor Egg Pregnancies
2. Youre Not Alone: How Mothers of Children Born with Rare Condition Comfort and Support Each Other on CarePages.com
3. Some cases of autism may be traced to the immune system of mothers during pregnancy
4. Mothers and Youth Sports Nationwide Push for FabricAide in Response to MRSA Threat
5. Mothers stress may increase childrens asthma
6. Smoking and depression often co-occur in new mothers
7. HIV drug resistance risk in mothers reduced by combination of common drugs
8. Overweight mothers run greater risk of having hyperactive children
9. Hip size of mothers linked to breast cancer in daughters
10. Mothers Know Best: NFL Moms Team With Eddie George to Showcase a Better Way to a Healthier Lifestyle
11. FDA Warns of Codeine Risk for Some Nursing Mothers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/26/2016)... ... June 26, 2016 , ... PawPaws brand pet supplements owned ... developed to enhance the health of felines. The formula is all-natural and is made ... in the PawPaws Cat Kidney Support Supplement Soft Chews are Astragalus Root ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... The temporary closing of Bruton Memorial Library ... City Observer , brings up a new, often overlooked aspect of head lice: the parasite’s ... for fumigation is not a common occurrence, but a necessary one in the event that ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... On Friday, ... presented a Bronze Wellness at Work award to iHire in recognition of their exemplary ... part of the 7th annual Maryland Workplace Health & Wellness Symposium at the BWI ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... Marcy was in a crisis. Her ... would lash out at his family verbally and physically. , “When something upset him, he ... he would use it. He would throw rocks at my other children and say he ...
(Date:6/24/2016)... NY (PRWEB) , ... June 24, 2016 , ... Topical BioMedics, Inc, makers of Topricin ... companies that call for a minimum wage raise to $12 an hour by 2020 and ... This will restore the lost value of the minimum wage, assure the wage floor does ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016 The Academy of Managed Care ... that would allow biopharmaceutical companies to more easily ... make formulary and coverage decisions, a move that addresses ... medicines. The recommendations address restrictions in the ... the drug label, a prohibition that hinders decision makers ...
(Date:6/24/2016)... -- According to a new market research ... Safety Pen Needles), Needle Length (4mm, 5mm, 6mm, 8mm, ... Purchase (Retail, Non-Retail) - Trends & Global Forecasts to ... for the forecast period of 2016 to 2021. This ... 2021 from USD 1.65 Billion in 2016, growing at ...
(Date:6/23/2016)... -- MedSource announced today that it has selected Datatrial,s ... choice.  This latest decision demonstrates MedSource,s commitment to ... by offering a state-of-the-art electronic data capture (EDC) ... the EDC platform of choice in exchange for ... long been a preferred EDC platform by our ...
Breaking Medicine Technology: