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Most women who have double mastectomy don't need it, U-M study finds
Date:11/27/2012

ANN ARBOR, Mich. About 70 percent of women who have both breasts removed following a breast cancer diagnosis do so despite a very low risk of facing cancer in the healthy breast, new research from the University of Michigan Comprehensive Cancer Center finds.

Recent studies have shown an increase in women with breast cancer choosing this more aggressive surgery, called contralateral prophylactic mastectomy, which raises the question of potential overtreatment among these patients.

The study found that 90 percent of women who had surgery to remove both breasts reported being very worried about the cancer recurring. But, a diagnosis of breast cancer in one breast does not increase the likelihood of breast cancer recurring in the other breast for most women.

"Women appear to be using worry over cancer recurrence to choose contralateral prophylactic mastectomy. This does not make sense, because having a non-affected breast removed will not reduce the risk of recurrence in the affected breast," says Sarah Hawley, Ph.D., associate professor of internal medicine at the U-M Medical School.

Hawley will present the findings Nov. 30 at the American Society of Clinical Oncology's Quality Care Symposium.

The study authors looked at 1,446 women who had been treated for breast cancer and who had not had a recurrence. They found that 7 percent of women had surgery to remove both breasts. Among women who had a mastectomy, nearly 1 in 5 had a double mastectomy.

In addition to asking about the type of treatment, researchers asked about clinical indications for double mastectomy, including the patients' family history of breast and ovarian cancer and the results of any genetic testing.

Women with a family history of two or more immediate family members (mother, sister, daughter) with breast or ovarian cancer or with a positive genetic test for mutations in the BRCA1 or BRCA2 genes may be advised to consider ha
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Contact: Nicole Fawcett
nfawcett@umich.edu
734-764-2220
University of Michigan Health System
Source:Eurekalert  

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Most women who have double mastectomy don't need it, U-M study finds
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