Navigation Links
Most early-stage breast cancer patients may not need radiation after mastectomy
Date:3/6/2010

ducted in the 1960s to 1980s showed both a survival benefit, and a decreased risk of LRR for women with node positive breast cancer. These study findings shifted clinical practice: the National Comprehensive Cancer Network altered their medical guidelines in 2007 to suggest that stage I and II breast cancer patients with one to three lymph node metastases "strongly consider" radiation post-mastectomy.

"We have entered a new era of breast cancer diagnosis and treatment. Modern day advances in all modalities have been dramatic and, collaboratively, have had a significant impact on recurrence and survival. Given these advances, the goal of our study was to assess the present-day LRR risk in women who present with smaller breast tumors and metastases to fewer lymph nodes," said Kuerer.

Kuerer and his colleagues studied clinical and pathological factors from 1,022 stage I or II breast cancer patients who received a mastectomy at M. D. Anderson between 1997 and 2002. Of those women, 79 percent had no lymph node involvement, 26 percent had 1-3 positive lymph nodes, with the majority having just one positive node. None received post-mastectomy radiation and/or pre-operative chemotherapy; 77 percent received post-operative chemotherapy and/or hormonal therapy. The median age was 54 years and the median follow up time was 7.5 years.

The researchers found that there was no statistical difference in the 10-year risk of LRR in women without lymph node spread versus those with spread to one node - 2.1 percent to 3.3 percent, respectively.

The only independent risk factor for LRR was age; patients age 40 and younger, regardless of node involvement, were at significant increased risk for LRR.

"For these younger women, not less, but more treatment may be needed," said Rajna Sharma, M.D., a fellow in M. D. Anderson's Department of Surgical Oncology, who presented the findings.

"For the overwhelming majority of early-stage breas
'/>"/>

Contact: Lindsay Anderson
lindsay.anderson@gabbe.com
212-220-4444
University of Texas M. D. Anderson Cancer Center
Source:Eurekalert  

Page: 1 2 3

Related medicine news :

1. Researchers find biomarkers in saliva for detection of early-stage pancreatic cancer
2. Ultrasound plus proteomic blood analyses may help physicians diagnose early-stage ovarian cancer
3. Wistar-led research team discovers genetic pattern that indicates early-stage lung cancer
4. Early-stage, HER2-positive breast cancer patients at increased risk of recurrence
5. Genomic Health Announces Data Confirming Manual Microdissection of Biopsy Cavities Is Essential for Accurate Recurrence Risk Assessment in Early-Stage Breast Cancer Patients
6. FDA Clears Hologics MammoSite(R) ML Radiation Therapy System for the Treatment of Early-Stage Breast Cancer
7. Office Ergonomics Book Reveals Early-Stage Solutions
8. Early-stage lung cancer identified using computer-aided system
9. More women with early-stage breast cancer choosing double mastectomies
10. Best Practice Database Adds Research Highlighting the Value of Portfolio Management in Early-Stage Commercialization and Customer-Focused Software Quality Assurance
11. Best Practice Database adds Research Highlighting the Value of Internal Consulting and Early-Stage Commercialization Groups in the Pharmaceutical Industry
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Most early-stage breast cancer patients may not need radiation after mastectomy
(Date:8/28/2014)... glue directly on the nerve stumps, but this method ... glue to easily invade the nerve ends. Ordinarily, nerve ... the nerve ends into the conduit because the nerve ... and co-workers from the General Hospital of Chinese PLA ... defined the best parameters for its use through in ...
(Date:8/28/2014)... can be treated with nasal septum cells. Researchers at ... that cells taken from the nasal septum are able ... and can thus repair articular cartilage defects. The nasal ... joint environment is associated with the expression of so-called ... has published the research results together with the ...
(Date:8/28/2014)... One in every 200 Ontarians has been diagnosed with ... living with the disease increasing by 64 per cent ... researchers at the Institute for Clinical Evaluative Sciences (ICES), ... Ottawa Hospital Research Institute. That puts Ontario in the ... The study, published this week in Inflammatory Bowel ...
(Date:8/28/2014)... rheumatoid arthritis patients in the study who were on ... not take them as prescribed in the first six ... from 60 hospitals around the UK involved in the ... for Genetics and Genomics at The University of Manchester, ... the drugs correctly, known as ,non-adherence, reduced their effectiveness ...
(Date:8/28/2014)... 28, 2014 BCC Research ( http://www.bccresearch.com ... SYSTEMS: TECHNOLOGIES AND GLOBAL MARKETS , the global market ... in 2013. Driven by the need for replacement of ... in emerging geographies, the market is expected to grow ... (CAGR) of 8.5% from 2013 through 2018. , While ...
Breaking Medicine News(10 mins):Health News:From nose to knee: Engineered cartilage regenerates joints 2Health News:Ontario has one of the highest rates of IBD in the world 2Health News:Arthritis patients failing to take expensive medication, according to new research 2Health News:Global Market for Surgical Navigation Systems Expected to Reach $631.9 Million in 2018; ENT Systems Segment Leading With 10.4% CAGR 2Health News:Global Market for Surgical Navigation Systems Expected to Reach $631.9 Million in 2018; ENT Systems Segment Leading With 10.4% CAGR 3
... NEW YORK (Nov. 22 2009) -- Physician-scientists from Weill Cornell ... to be a powerful target for the treatment of non-Hodgkin,s ... blood cells. By exploiting this mechanism, researchers have been able ... animal models. Promising results have led to the design ...
... ... can be both fun and joyous. It can also be stressful and tiring ... foods -- factors that can, over time, increase your risk of cancer. That,s ... 10 Food Tips that can help ensure a happier, more healthful holiday season, ...
... , WASHINGTON, Nov. 21 DNC Chairman ... to begin full debate of health insurance reform legislation. ... Senate took another historic step on the road to enacting ... will now have an opportunity to debate the health reform ...
... , , Association Discusses Key ... Reform , ST. CHARLES, Ill., Nov. 21 ... Affordable Health Care for America Act (H.R. 3962), and the ... decisive steps to fix our nation,s broken health care system. ...
... , ... addictive game, SplitWords, is now available on the iPhone and iPod Touch. , ... Mountain View, CA (PRWEB) November 21, 2009 ... iPod Touch. Split Words is designed to help banish that ,tip of the tongue, syndrome ...
... , Pioneering Neurologist Closer to Understanding ... Dr. Jeremy Schmahmann, Professor of Neurology at Harvard Medical ... Boston, on Thursday, November 19, presented his laboratory,s research ... the launch of the MINDlink Foundation. , Dr. Schmahmann ...
Cached Medicine News:Health News:New cancer target for non-Hodgkin's lymphoma 2Health News:Top 10 Food Tips for the Holidays from the National Foundation for Cancer Research 2Health News:Top 10 Food Tips for the Holidays from the National Foundation for Cancer Research 3Health News:Democratic National Committee Chairman Tim Kaine's Statement on the Senate's Vote to Proceed to Full Floor Debate of Health Insurance Reform Legislation 2Health News:AARP Hosts Rep. Bill Foster In Health Care Reform Forum 2Health News:HAPPYneuron releases iPhone Brain Game 2Health News:HAPPYneuron releases iPhone Brain Game 3Health News:MINDlink Foundation Launches to Connect the Cerebellum to Cures 2
(Date:8/28/2014)... 2014 According to a new ... (RFID) Market (Tags, Readers, Middleware, Printers and Cabinets) - ... 2014 - 2020" the global radiofrequency identification (RFID) market ... is expected to grow at a CAGR of 13.9% ... of USD 5.3 billion in 2020. Browse ...
(Date:8/28/2014)... /PRNewswire-iReach/ -- Gateway Analytical announced today that they ... Annual Global Pharma Manufacturing Summit in ... The Global Pharma Manufacturing Summit offers a networking ... biologic pharmaceutical manufacturing. The conference is focused on ... such as the increasing pressure to grow and ...
(Date:8/28/2014)... Orthopaedics, the Official Joint Replacement Products of the PGA TOUR ... to golf fans at the next stop of the FedEx ... company,s fan destination – "The Stryker Mobility Zone" – will ... TPC Boston in Norton, MA starting ... the Deutsche Bank Championship, Stryker will be providing golf fans ...
Breaking Medicine Technology:Radiofrequency Identification (RFID) Market in Healthcare is Expected to Reach USD 5.3 Billion Globally by 2020: Transparency Market Research 2Radiofrequency Identification (RFID) Market in Healthcare is Expected to Reach USD 5.3 Billion Globally by 2020: Transparency Market Research 3Radiofrequency Identification (RFID) Market in Healthcare is Expected to Reach USD 5.3 Billion Globally by 2020: Transparency Market Research 4Radiofrequency Identification (RFID) Market in Healthcare is Expected to Reach USD 5.3 Billion Globally by 2020: Transparency Market Research 5Gateway Analytical to Promote Particulate Identification Services at the 9th Annual Global Pharma Manufacturing Summit 2Gateway Analytical to Promote Particulate Identification Services at the 9th Annual Global Pharma Manufacturing Summit 3Stryker, Official Joint Replacement Products Of The PGA TOUR, Heads To Boston For The Deutsche Bank Championship 2Stryker, Official Joint Replacement Products Of The PGA TOUR, Heads To Boston For The Deutsche Bank Championship 3Stryker, Official Joint Replacement Products Of The PGA TOUR, Heads To Boston For The Deutsche Bank Championship 4Stryker, Official Joint Replacement Products Of The PGA TOUR, Heads To Boston For The Deutsche Bank Championship 5
... Dec. 12, 2010 Pfizer Inc. (NYSE: ... vaccine [13-valent, adsorbed]) was introduced into the first childhood ... world under the auspices of the Advance Market Commitment ... is an innovative program which involves private-public partnerships to ...
...  The Office of Inspector General for the Export-Import Bank ... Miami resident Yader A. Padilla, 59, was sentenced to 24 ... U.S. District Judge Paul C. Huck in U.S. District Court ... his role in defrauding the Ex-Im Bank.  Padilla had previously ...
Cached Medicine Technology:Young Children In Developing World Receive Accelerated Access to Pfizer's Prevenar 13 Vaccine 2Young Children In Developing World Receive Accelerated Access to Pfizer's Prevenar 13 Vaccine 3Young Children In Developing World Receive Accelerated Access to Pfizer's Prevenar 13 Vaccine 4Young Children In Developing World Receive Accelerated Access to Pfizer's Prevenar 13 Vaccine 5Distributed by the Export-Import Bank of the United States On Behalf of the Independent Office of Inspector General 2
... Bypass 6200: Direct connection to ... OCD870C CGA 870 Regulator , ... OCD2001-18 Carrying Pouch , OCD2001-11 ... M-6 Cylinder Carrying Bag , ...
... CVD Diamond Knives. New advancements in diamond ... to be used at a more economical ... reapproximation, enhances healing, and insures a superior ... and are available in a variety of ...
The New Easy-To-Use Disposable Diamond Knife Cleaning System Can Remove Even Baked-On Debris In Seconds. It Is Much More Effective Than Steam Or Blocks Of Styrofoam, Much Safer For Employees As Wel...
... To Safely And Easily Cut Foldable ... Designed To Cut And Remove Even ... With One Instrument.,New Miniaturized Profile Allows ... For Explantation Of A Silicone Lens.,Available ...
Medicine Products: