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Most Childhood Cancer Survivors Have Healthy Babies
Date:10/6/2009

those treated with a combination of chemotherapy, surgery and radiation.

"Children and adolescents with cancer can be reassured that we did not find an increased risk of malformations or infant death among their first subsequent offspring," the researchers concluded. "The increased occurrence of low birth weight and preterm delivery among childhood cancer survivors and of preterm delivery among young genital tract carcinoma survivors that we and others have observed may indicate relatively less severe potential problems among offspring. However, these outcomes can still greatly affect families, are associated with significantly increased costs and indicate a need for close monitoring of pregnancies among childhood and adolescent cancer survivors."

The study appears in the October issue of the journal Archives of Pediatrics & Adolescent Medicine.

Another study in the same issue of the journal looked at 470 children of men who had childhood cancer and found that the infants had a "borderline risk" of weighing less than 2,500 grams at birth, especially if their father had cancer at an early age or underwent chemotherapy.

"However, they were not at risk of being born prematurely, being small for gestational age, having malformations or having an altered male to female ratio," wrote Dr. Eric J. Chow, of the Fred Hutchinson Cancer Research Center, and colleagues.

In general, female partners of male childhood cancer survivors weren't at increased risk for pregnancy complications, the study found. However, women did have a higher risk of preeclampsia if their male partner had certain types of childhood cancer, especially brain tumors.

"Most pregnancies resulting in live births among partners of male childhood cancer survivors were not at significantly greater risk of complications versus comparison subjects. However, our findings of increased low birth weight and preeclampsia associated with some diagnos
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