Navigation Links
Morning UV exposure may be less damaging to the skin
Date:10/24/2011

(Embargoed) CHAPEL HILL Research from the University of North Carolina at Chapel Hill suggests that the timing of exposure to UV rays early in the morning or later in the afternoon can influence the onset of skin cancer.

The study, performed in mice, found that exposure to UV radiation in the morning increased the risk of skin cancer by 500 percent over identical doses in the afternoon. Although mice and humans both reside on a 24-hour day, the "circadian" clocks of these nocturnal and diurnal creatures run counter each other. This key difference in biology means that humans are most protected from the sun's harmful rays when mice are most susceptible, and vice versa.

"Therefore, our research would suggest that restricting sunbathing or visits to the tanning booth to morning hours would reduce the risk of skin cancer in humans," said senior study author Aziz Sancar, M.D., PhD, a member of the UNC Lineberger Comprehensive Cancer Center and Sarah Graham Kenan professor of biochemistry and biophysics in the UNC School of Medicine. Sancar is also a member of the National Academy of Sciences and the Turkish Academy of Sciences "However, further studies in humans are needed before we can make any definitive recommendations."

Sancar has previously shown that a protein called XPA, responsible for repairing the DNA damage wrought by UV radiation, waxes and wanes throughout the day. In a study published online the week of October 24-30 in the Proceedings of the National Academy of Sciences, he and his colleagues looked to see if the cyclical nature of this DNA repair molecule had an influence on the onset of skin cancer.

They exposed two groups of mice to UV radiation either at 4 a.m. or at 4 p.m. and waited for cancer to develop. Mice irradiated when the repair activity was at its minimum developed tumors much faster and at five-fold higher frequency compared with mice exposed to UV when the protein's repair function was at its maximum.

The researchers predict that humans will have a higher rate of DNA repair in the morning and would be less prone to the carcinogenic effect of UV radiation in the morning hours. They plan to measure actual DNA repair rates in the skin of human volunteers to confirm that morning sun is safest for humans.


'/>"/>

Contact: Les Lang
llang@med.unc.edu
919-966-9366
University of North Carolina School of Medicine
Source:Eurekalert  

Related medicine news :

1. Lack of morning light keeping teenagers up at night
2. Severe Morning Sickness Passed From Moms to Daughters
3. O2 Media's Hit Morning TV Show ‘The Balancing Act' Welcomes Atkins Nutritionals to the Program
4. O2 Media's Hit Morning Show ‘The Balancing Act' Welcomes the Arthritis Foundation to the Program
5. O2 Media's Hit Morning Show ‘The Balancing Act' Welcomes Resident Chef Jeremy Hanlon to the Program
6. O2 Media's Hit Morning Show ‘The Balancing Act' Welcomes Dexter Russell, Inc. to the Program
7. O2 Media's Hit Morning TV Show ‘The Balancing Act' Welcomes Absolute Miracle Cream to the Program
8. O2 Media's Hit Morning Show ‘The Balancing Act' Welcomes HSA Bank to the Program
9. O2 Media's Hit Morning Show ‘The Balancing Act' Welcomes Dr. Bob Arnot to the Program
10. FDA Panel to Vote on New Morning After Pill
11. FDA Panel Backs New Morning After Pill
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Morning UV exposure may be less damaging to the skin
(Date:4/29/2016)... ... April 29, 2016 , ... A new ... with severe congenital diaphragmatic hernia have better survival rates if surgery is performed ... (CDH)—a condition where the diaphragm fails to form completely, letting abdominal organs into ...
(Date:4/29/2016)... PA (PRWEB) , ... April 29, 2016 , ... ... announced that student team BioCellection won the $30,000 Perlman Grand Prize of the ... Prize, the Gloeckner Undergraduate Award, the Michelson People’s Choice Award, and the Committee ...
(Date:4/29/2016)... ... April 29, 2016 , ... World Patent Marketing ... an exercise invention which aids in proper muscle development. , "The Gym & ... Creative Director of World Patent Marketing. "Globalization has threatened the future growth of ...
(Date:4/29/2016)... ... ... the deadliest type of skin cancer. Although only about 1 percent of skin cancer cases ... 10,000 people are expected to die of melanoma this year. The risk increases with age, ... most commonly diagnosed cancers in young women. A recent breakthrough in genetic studies may give ...
(Date:4/29/2016)... New York, NY (PRWEB) , ... April 29, 2016 , ... New York City based ... surgery . This surgery is a very effective way to treat obstructive sleep apnea. Dr. ... , Orthognathic surgery is a procedure that involves one or both jaw bones. This ...
Breaking Medicine News(10 mins):
(Date:4/28/2016)... , April 28, 2016 ... consumer insights on healthcare, announced today that it has ... report Cool Vendor in Life Sciences, 2016, ... 15, 2016.  The report focuses on life-science- oriented analytics, ... insight from patients and doctors, confirm medication ingestion, and ...
(Date:4/28/2016)... , April 28, 2016  ValGenesis, ... Lifecycle Management Solutions (VLMS) today announced that ... services for sufferers of chronic kidney failure ... to manage their corporate validation process. The ... a software solution to manage their validation ...
(Date:4/27/2016)... 2016   ... sur le trimestre, soutenu par une croissance de ... Croissance de +16% des ventes aux hôpitaux et ... Technologies (Euronext : MKEA, FR0010609263 ; OTCQX : MKEAY), inventeur de ... son chiffre d,affaires pour le premier trimestre clos ...
Breaking Medicine Technology: