Navigation Links
Morning UV exposure may be less damaging to the skin

(Embargoed) CHAPEL HILL Research from the University of North Carolina at Chapel Hill suggests that the timing of exposure to UV rays early in the morning or later in the afternoon can influence the onset of skin cancer.

The study, performed in mice, found that exposure to UV radiation in the morning increased the risk of skin cancer by 500 percent over identical doses in the afternoon. Although mice and humans both reside on a 24-hour day, the "circadian" clocks of these nocturnal and diurnal creatures run counter each other. This key difference in biology means that humans are most protected from the sun's harmful rays when mice are most susceptible, and vice versa.

"Therefore, our research would suggest that restricting sunbathing or visits to the tanning booth to morning hours would reduce the risk of skin cancer in humans," said senior study author Aziz Sancar, M.D., PhD, a member of the UNC Lineberger Comprehensive Cancer Center and Sarah Graham Kenan professor of biochemistry and biophysics in the UNC School of Medicine. Sancar is also a member of the National Academy of Sciences and the Turkish Academy of Sciences "However, further studies in humans are needed before we can make any definitive recommendations."

Sancar has previously shown that a protein called XPA, responsible for repairing the DNA damage wrought by UV radiation, waxes and wanes throughout the day. In a study published online the week of October 24-30 in the Proceedings of the National Academy of Sciences, he and his colleagues looked to see if the cyclical nature of this DNA repair molecule had an influence on the onset of skin cancer.

They exposed two groups of mice to UV radiation either at 4 a.m. or at 4 p.m. and waited for cancer to develop. Mice irradiated when the repair activity was at its minimum developed tumors much faster and at five-fold higher frequency compared with mice exposed to UV when the protein's repair function was at its maximum.

The researchers predict that humans will have a higher rate of DNA repair in the morning and would be less prone to the carcinogenic effect of UV radiation in the morning hours. They plan to measure actual DNA repair rates in the skin of human volunteers to confirm that morning sun is safest for humans.


Contact: Les Lang
University of North Carolina School of Medicine

Related medicine news :

1. Lack of morning light keeping teenagers up at night
2. Severe Morning Sickness Passed From Moms to Daughters
3. O2 Media's Hit Morning TV Show ‘The Balancing Act' Welcomes Atkins Nutritionals to the Program
4. O2 Media's Hit Morning Show ‘The Balancing Act' Welcomes the Arthritis Foundation to the Program
5. O2 Media's Hit Morning Show ‘The Balancing Act' Welcomes Resident Chef Jeremy Hanlon to the Program
6. O2 Media's Hit Morning Show ‘The Balancing Act' Welcomes Dexter Russell, Inc. to the Program
7. O2 Media's Hit Morning TV Show ‘The Balancing Act' Welcomes Absolute Miracle Cream to the Program
8. O2 Media's Hit Morning Show ‘The Balancing Act' Welcomes HSA Bank to the Program
9. O2 Media's Hit Morning Show ‘The Balancing Act' Welcomes Dr. Bob Arnot to the Program
10. FDA Panel to Vote on New Morning After Pill
11. FDA Panel Backs New Morning After Pill
Post Your Comments:
Related Image:
Morning UV exposure may be less damaging to the skin
(Date:10/13/2017)... ... 2017 , ... Ellevate Network, the leading network for professional women, brought together ... equality at their inaugural Summit in New York City in June. The event was ... of over 3 million. To watch the Mobilize Women video, click here . ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... viewers the lowdown on sciatica in a new episode of "Success Files," which ... current events and innovation and investigates each subject in-depth with passion and integrity. ...
(Date:10/13/2017)... ... 13, 2017 , ... “America On The Brink”: the Christian history of the ... is the creation of published author, William Nowers. Captain Nowers and his wife, ... he spent thirty years in the Navy. Following his career as a naval ...
(Date:10/12/2017)... ... October 12, 2017 , ... Planet Fitness, one of the largest and fastest ... to open a flagship location in Covington, LA at 401 N. U.S. Highway 190, ... next to Office Depot in the Holiday Square shopping center. Its location allows it ...
(Date:10/12/2017)... ... October 12, 2017 , ... The American College of Medical Informatics (ACMI) ... FACMI, during the Opening Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s ... Morris F. Collen, a pioneer in the field of medical informatics, this prestigious award ...
Breaking Medicine News(10 mins):
(Date:9/27/2017)... NEW YORK , Sept. 27, 2017  DarioHealth Corp. (NASDAQ: ... data solutions, today announced that its MyDario product is expected to appear ... listings for when The Dr. Oz Show airs in your area: ... The nine-time Emmy award-winning, The ... ...
(Date:9/23/2017)... , Sept. 22, 2017 Janssen Biotech, ... complete response letter from the U.S. Food and Drug ... approval of sirukumab for the treatment of moderately to ... indicates additional clinical data are needed to further evaluate ... to severely active RA. ...
(Date:9/19/2017)... ARBOR, Mich. , Sept. 19, 2017 HistoSonics, Inc., a venture-backed medical device ... precise destruction of targeted tissues, announced three leadership team developments today:   ... Stopek, PhD ... ... Veteran medical device executive ...
Breaking Medicine Technology: