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More than Seventy Percent of Top US Hospitals Control Patient Temperature with High-Tech Arctic Sun(TM)
Date:3/10/2008

Automated non-invasive cooling avoids DVT danger; precise control of

rewarming key to averting brain damage

LOUISVILLE, Colo., March 10 /PRNewswire/ -- Led by the nation's top hospitals, adoption of the safest, most effective cooling technology-the non- invasive Arctic Sun(R)-is increasing rapidly. The number of top hospitals inducing hypothermia and then rewarming their critically ill patients with the Arctic Sun rose to more than 72 percent in 2007 from 60 percent the previous year.

Thirteen of the 18 top-ranked U.S. News & World Report hospitals (72.2 percent); 16 of the top 20 heart programs (80 percent); and 16 of the top 20 neurology programs cool and rewarm patients with Medivance's precise, automated high-tech Arctic Sun device.

"Fever kills brain cells. This notion that 'temperature is brain' has become a key concept used in the management of patients in our NeuroICU , says Dr. Andrew Kofke, Co-Director of Neurocritical Care at the Hospital of the University of Pennsylvania, which is ranked among the nation's best overall hospitals. "I believe state -of-the-art temperature management, using devices such at the Arctic Sun cooling system, combined with pharmacological aids, is an essential element in prevention of secondary brain damage after a brain injury."

A growing body of clinical data published in the New England Journal of Medicine and other top-tier journals indicates that lowering body temperature to therapeutic levels, followed by slow rewarming, limits neurologic damage in a wide range of critically ill patients.

"Adoption of the Arctic Sun by the vast majority of the nation's top hospitals demonstrates that its the best temperature management system available today and validates our premise that safe, non-invasive cooling coupled with the ability to rewarm slowly and precisely holds great promise in improving patient outcomes," says Medivance CEO Robert Kline.

The Arctic Sun transfers up to five times more energy than conventional products such as water blankets, wraps or ice packs. Its ArcticGel(TM) pads cool rapidly, the result of direct thermal conduction between circulating water and a patient's skin.

The number of teaching and community hospitals that cool with the Arctic Sun is also growing rapidly due to its ease of use, speed with which nurses can initiate the therapy, and the far greater safety of technologically advanced surface cooling. Non-invasive temperature control does not put patients at unnecessary risk of deep vein thrombosis (DVT), bleeding or infection associated with invasive devices.

Cooling a standard of care

In 2005, the American Heart Association (AHA) issued recommendations and guidelines for inducing mild hypothermia in comatose survivors of cardiac arrest, making cooling a standard of care.

About Medivance's Arctic Sun

The non-invasive Arctic Sun Temperature Management System precisely monitors and maintains core body temperature in a therapeutic range, between 320 and 38.50 Celsius (approximately 89.60 to 101.30 Fahrenheit) with the potential to minimize damage to the heart and brain. The Arctic Sun has received 510 (k) FDA clearance in the U.S., the European Union's CE Mark, and marketing approval in Japan. Medivance develops and manufactures non-invasive, proprietary therapeutic temperature management solutions. More information at http://www.medivance.com.


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SOURCE Medivance
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