Navigation Links
More efficient way to make popular prescription medication
Date:1/23/2013

In a demonstration of the power of green chemistry, scientists are reporting development of a new and more efficient process for making one of the most costly and widely used medications for severe mental illness. Described in a report in the journal ACS Sustainable Chemistry & Engineering, it produces larger amounts of the medication than the existing commercial process while reducing the use of solvents and other potentially toxic substances.

Vijayavitthal T. Mathad and colleagues point out that paliperidone, marketed under the brand name Invega, is one of a new generation of medicines for schizophrenia, a severe form of mental illness. Paliperidone has advantages over other medicines, but the current process for making it is expensive and inefficient, contributing to the drug's cost about $18 per tablet in the United States. The process also requires use and disposal of large amounts of solvents that require special handling.

They describe development of a new recipe for making paliperidone. It not only yields larger amounts of the medicine, but uses less solvent and involves an innovative and environmentally friendly method for purifying the medication and for the control and removal of critical impurities that result from the process and carryover from raw materials. The sustainability of the process lies in its capability to withstand the cost pressure when the drug becomes completely generic, the authors said. Reducing the raw material cost not only makes it sustainable but it should be environmentally and production-friendly.


'/>"/>
Contact: Michael Bernstein
m_bernstein@acs.org
202-872-6042
American Chemical Society
Source:Eurekalert

Page: 1

Related medicine news :

1. Not all stem cells are equally efficient for use in regenerative medicine
2. Successful results against human leishmaniasis with a more efficient and economic vaccine
3. New technology for a more efficient treatment of Pompe disease and other metabolic disorders
4. Researchers will employ microscopic clay minerals to design more efficient and less toxic drugs
5. Lorna Kleidman Responds to an Article About Four Popular Exercises to Try in the New Year
6. Popularity of Walk-In Retail Health Clinics Growing: Poll
7. Dr. Sam Speron Discusses The Growing Popularity of The Mommy Makeover
8. TruckGamesParking.com, a Popular Website of Free Motorbike Games, Announced its New Website
9. Atlanta Plastic Surgeon Dr. David Whiteman Says Increased Popularity of Ethnic Rhinoplasty, Indicated by Latest ASPS Statistics, Emphasizes Need for Experienced Surgeons
10. Pharmacy researcher finds most popular weight-loss drug strongly alters other drug therapies
11. Diet Reviews Website 4maximumhealth.com Introduces Lucrative Savings on Popular Diet and Exercising Programs to Help People Stay Fit in the New Year
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... June 25, 2016 , ... On Friday, June 10, Van Mitchell, Secretary ... Work award to iHire in recognition of their exemplary accomplishments in worksite health promotion. ... Maryland Workplace Health & Wellness Symposium at the BWI Marriott in Linthicum Heights. iHire ...
(Date:6/24/2016)... ... June 24, 2016 , ... June 19, 2016 is World Sickle Cell Observance ... and the benefits of holistic treatments, Serenity Recovery Center of Marne, Michigan, ... Disease. , Sickle Cell Disease (SCD) is a disorder of the red blood cells, ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda ... orthodontic treatment. Dr. Cheng has extensive experience with all areas of orthodontics, including ... accelerated osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. ...
(Date:6/24/2016)... Norcross, Georgia (PRWEB) , ... June 24, 2016 ... ... Year” awards today at the Clinical Decision Making in Emergency Medicine conference in ... who have authored journal articles published in Emergency Medicine Practice and ...
(Date:6/24/2016)... ... June 24, 2016 , ... National recruitment firm Slone Partners is ... sequencing and genomics experience, as Vice President of North American Capital Sales at ... for leading the sales team in the commercialization of the HTG EdgeSeq system and ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... June 24, 2016 Research and Markets ... for Companion Diagnostic Tests" report to their offering. ... Companion Diagnostics The World Market for Companion ... medicine diagnostics. Market analysis in the report includes the following: ... (In Vitro Diagnostic Kits) by Region (N. America, EU, ROW), ...
(Date:6/23/2016)... HOUSTON , June 23, 2016  MedSource ... platform as its e-clinical software solution of choice.  ... the best possible value to their clients by ... nowEDC.  The preferred relationship establishes nowEDC as the ... pricing for MedSource,s full-service clients.  "nowEDC has long ...
(Date:6/23/2016)... Roche (SIX: RO, ROG; OTCQX: RHHBY) announced ... BRAHMS PCT (procalcitonin) assay as a dedicated testing solution ... this clearance, Roche is the first IVD company in ... sepsis risk assessment and management. PCT is ... levels in blood can aid clinicians in assessing the ...
Breaking Medicine Technology: