Navigation Links
More compelling evidence on why earlier HIV treatment lengthens survival
Date:4/2/2009

Seattle A study showing improved survival of starting antiretroviral treatment earlier than current U.S. recommendations is being reported in the April 30 issue of the New England Journal of Medicine. The study found that not starting HIV patients at a CD4 count greater than 500 cells per cubic millimeter increased risk of death by 94 percent.

"The question of when to start antiretroviral therapy has been one of the key controversies in HIV care for over a decade" said University of Washington's Dr. Mari Kitahata, the lead researcher on the study. "Our study adds a lot of weight to the growing body of evidence that starting treatment earlier in HIV disease prolongs survival."

Current U.S. guidelines recommend treatment for asymptomatic patients who have a CD4 count of less than 350. However, these guidelines lack data from randomized clinical trials regarding the timing of antiretroviral therapy.

Since 1996, when potent antiretroviral therapy was introduced and recommended for asymptomatic HIV patients with a CD4 count less than 500 cells per cubic millimeter, there has been uncertainty about when to start treatment.

The article, "Effect of Early versus Deferred Antiretroviral Therapy for HIV on Survival," reports on two analyses of 17,517 asymptomatic patients with HIV infection receiving care between 1996 and 2006. The data were gathered through a recent collaboration of 22 research groups in more than 60 sites in the United States and Canada -- the North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD).

In order to study the impact of earlier initiation of therapy, researchers needed a large number of patients at high CD4+ counts who are observed for a long period of time to a definitive endpoint of death. Because of the combined effort of one of the largest collaborations of HIV cohorts and researchers, researchers had the data to examine the effect of early AIDS treatment.

<
'/>"/>
Contact: Mari Kitahata, MD, MPH
kitahata@u.washington.edu
206-744-3677
University of Washington - Health Sciences/UW News, Community Relations & Marketing
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. The Compelling Evidence-Based Case for Hospital IT Investments: Complimentary Webinar
2. Partnership for Prevention: CDC Report Shows Compelling Need for FDA Regulation of Tobacco
3. USA TODAY Weight-Loss Challenge Returns For 5th Year With Eight Weeks of Compelling Stories and Online Features
4. Altrazeal(TM) Clinical Evidence to be Presented at The American Professional Wound Care Association (APWCA) National Clinical Conference 2009
5. Kaiser Permanente Data Provides Strong Evidence for Continued Value of Combined Pap and HPV Testing
6. MEDai Enhances Chronic Care Management with Real-Time, Evidence-Based Medicine Guideline Analysis
7. American Dental Association Launches Evidence-Based Dentistry Web Site
8. According to Frost & Sullivan, Mounting Clinical Evidence Underlines Benefits of Bone Growth and Spinal Fusion Stimulators
9. Genetic evidence points to potential therapeutic bypass for autoimmune process
10. New evidence suggests electric hand dryers in public toilets pose health risk
11. Clinical Evidence Grows in Support of CyberKnife Treatment for Intracranial and Extracranial Tumors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... Ligament (ACL) reconstructions occur more than 200,000 times a ... a new ligament may determine how long you stay ... at the Annual Meeting of the American Orthopaedic Society ... results highlight that in a young athletic population, allografts ... using autografts (tissue harvested from the patient)," said Craig ...
(Date:7/11/2014)... With the maturity and development of ... the installation rate of Chinese car electric window regulators ... exceeded 88% and the demand outnumbered 75 million pieces, ... years, Chinese car electric window regulator market will present ... size is expected to exceed 110 million pieces, with ...
(Date:7/11/2014)... TX (PRWEB) July 11, 2014 Avery ... their customers and to show more about their services ... http://www.kennrenner.com/buyaveryranch/ and view their home videos online, their ... Avery Ranch is Austin, Texas’ premiere golf course community ... city limits of Austin. Avery Ranch features an award ...
(Date:7/11/2014)... the experienced dressmaker in the world, has become one ... to beach wedding dresses . Recently, the firm ... in its online shop. Included in the new range ... has been considered as one of the best garment ... spokesman, BellasDress provides superb special occasion gowns and great ...
(Date:7/11/2014)... Rockville, MD (PRWEB) July 11, 2014 ... Shady Grove Fertility’s Annandale, VA office joined ... Buddy Check 9 to educate the audience about the ... with oncologists to make motherhood possible for ... Grove Fertility and oncologists treat patients in the developing ...
Breaking Medicine News(10 mins):Health News:ACL reconstructions may last longer with autografts 2Health News:China Car Electric Window Regulator Industry to Grow at CAGR of 10% to 2017 Says a New Research Report at ChinaMarketResearchReports.com 2Health News:China Car Electric Window Regulator Industry to Grow at CAGR of 10% to 2017 Says a New Research Report at ChinaMarketResearchReports.com 3Health News:China Car Electric Window Regulator Industry to Grow at CAGR of 10% to 2017 Says a New Research Report at ChinaMarketResearchReports.com 4Health News:Avery Ranch Announces Their New Website to Better Connect with Customers 2Health News:BellasDress Emerges As Popular Online Supplier Of 2014 Beach Wedding Dresses 2Health News:Baby After Cancer Is a Reality as Shady Grove Fertility Provides Successful Treatment for Cancer Survivors 2Health News:Baby After Cancer Is a Reality as Shady Grove Fertility Provides Successful Treatment for Cancer Survivors 3Health News:Baby After Cancer Is a Reality as Shady Grove Fertility Provides Successful Treatment for Cancer Survivors 4
... CHAPEL HILL, N.C. By the age of 20, most people ... recently it was assumed that skeletal enlargement elsewhere in the body ... researchers at the University of North Carolina at Chapel Hill has ... pelvis ("hipbones") does continue to widen as people advance in age ...
... last decade toward a deeper understanding and improved ... that underlie this complex array of conditions and ... On June 2-3, 2011, leading and emerging investigators ... pain and experts in the clinical development of ...
... first time, results on the impact of gaming devices on ... the EULAR 2011 Annual Congress. Data comparing two schools in ... pain following long term use of gaming devices and mobile ... health. , The study, involving 257 students, highlights that a ...
... By Maureen Salamon HealthDay Reporter , TUESDAY, May ... baked or broiled also protects against developing heart failure, a ... women for an average of 10 years found that those ... as five or more servings per week -- had a ...
... 25 (HealthDay News) --,The ability of men and women to ... their romantic relationships can be traced back to their early ... 78 people aged 20 or 21 and their heterosexual partners ... researchers already had data on the participants from when they ...
... tend to have lower earnings and labor force participation ... disability benefits, a new study finds. Rejected applicants ... accepted applicants, according to the research led by economist ... average, the study found, those rejected for benefits made ...
Cached Medicine News:Health News:Pelvic widening continues throughout a person's lifetime, UNC study 2Health News:Investigators explore new frontiers in the development of tomorrow's pain medicines 2Health News:Children experience wrist and finger pain when using gaming devices and mobile phones over time 2Health News:Cooked Right, Fish Can Help a Woman's Heart 2Health News:Cooked Right, Fish Can Help a Woman's Heart 3Health News:Capacity for Commitment May Start in Early Childhood 2Health News:Study finds much different work histories for disability rejects, beneficiaries 2
(Date:7/10/2014)... 2014 Yesterday, former Congressman Patrick ... manufacturing facility. Rep. Kennedy and Dick Moberg ... cutting-edge research in neurological disease and treatment. ... advocate, Garen Staglin , created One Mind, ... changes that will radically accelerate the development and ...
(Date:7/10/2014)... 2014   LabStyle Innovations Corp . (OTCQB:DRIO), developer ... the appointment of Professor Richard B. Stone ... of Directors. Prof. Stone brings over ... LabStyle as an entrepreneur, venture capitalist public, company ... expert. He currently serves on the board of ...
(Date:1/15/2014)... , Jan. 15, 2014 Most osteoporosis patients want ... a recent online survey* sponsored by Mission Pharmacal Company. ... National Osteoporosis Foundation online support community, revealed that 74 ... that comes in a form other than a pill ...
Breaking Medicine Technology:Representative Patrick Kennedy visits Moberg's medical device facility to discuss improvement in brain injury care 2LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 2LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 3LabStyle Innovations Welcomes Richard B. Stone to its Board of Directors 4Mission Pharmacal Conducts Online Survey of Osteoporosis Patients 2Mission Pharmacal Conducts Online Survey of Osteoporosis Patients 3
... Expands Enterprise Intelligence Systems to Healthcare Market, ... Booth #1841 --,Harris Corporation (NYSE: HRS ... has joined forces with Cancer Treatment,Services International ... of,radiation oncology. Harris will provide advanced imaging ...
... InteKrin Therapeutics, Inc.,a privately-held clinical stage biopharmaceutical ... novel drugs for the treatment of,diabetes, obesity ... has,initiated a Phase 2b study in diabetic ... non-TZD SPPARM (Selective Peroxisome,Proliferator-Activated Receptor Modulator). INT131 ...
Cached Medicine Technology:Harris Corporation Teams with Cancer Treatment Services International to Advance Oncology Treatment 2InteKrin Therapeutics Announces Initiation of Phase 2b Study in Type 2 Diabetes with INT131 2
... Professional Diagnostics is a leading provider of ... DFA test menu that includes kits for ... well as miscellaneous conjugates and components. Our ... wide assortment of substrates and kit sizes ...
... Diagnostics is a leading provider of immunofluorescence ... test menu that includes kits for autoimmune ... as miscellaneous conjugates and components. Our Impact ... assortment of substrates and kit sizes to ...
... Diagnostics is a leading provider of immunofluorescence ... test menu that includes kits for autoimmune ... as miscellaneous conjugates and components. Our Impact ... assortment of substrates and kit sizes to ...
... a leading provider of immunofluorescence assays, with ... that includes kits for autoimmune diseases, infectious ... conjugates and components. Our Impact IFA Test ... substrates and kit sizes to choose from. ...
Medicine Products: