Navigation Links
More New Drugs a Bad Fit With Grapefruit, Study Finds
Date:11/26/2012

ized in the stomach in the same way, the researchers said.

A small amount of grapefruit, even ingested hours before taking the medications, can increase the amount of the drug metabolized, which is like taking many doses at once, the researchers said.

The toxic effect can build when the drug is taken repeatedly. For example, if the cholesterol-lowering drug Zocor is combined with a 7-ounce glass of grapefruit juice once a day for three days, the drug in the bloodstream will increase 330 percent, Bailey said.

According to the report, drugs that can interact with grapefruit include:

  • Certain cholesterol-lowering statin drugs, such as Zocor (simvastatin), Lipitor (atorvastatin) and Pravachol (pravastatin),
  • Some blood pressure-lowering drugs, such as nifedipine (Nifediac and Afeditab),
  • Organ transplant rejection drugs, such as cyclosporine (Sandimmune and Neoral),
  • Certain cardiovascular drugs, such as amiodarone (Cordarone and Nexterone), clopidogrel and apixaban.

Because people older than 45 are the major buyers of grapefruit and are more likely than younger individuals to take a variety of medications, they are most at risk. Also, because of their advanced age, they are most vulnerable to the harmful reactions of grapefruit-drug combinations, the researchers said.

Dr. Gregg Fonarow, a spokesman for the American Heart Association and a professor of cardiology at the University of California, Los Angeles, said little is known about how often these adverse effects occur in real world practice. Further studies are necessary, he added.

"Patients taking medications where there are potentially serious adverse interactions should, in general, be advised to avoid consumption of moderate or large quantities of grapefruit, or together with their physician consider potential alternative medications that are not metabolized by the liver enzyme inhibited by grapefruit," Fonarow said.

'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Continued Use of ADHD Drugs May Reduce Criminal Behavior, Study Says
2. UAlberta prostate cancer researcher and team developing homing beacon drugs to target cancer cells
3. Can breast cancer cells reaction to cancer drugs be predicted?
4. Quick, high-volume test offers fast track in search for Alzheimers drugs
5. Structure of enzyme unravelled providing basis for more accurate design of chemotherapeutic drugs
6. Injectable sponge delivers drugs, cells, and structure
7. Game changer for arthritis and anti-fibrosis drugs
8. First trial in humans of minicells: A completely new way of delivering anti-cancer drugs
9. Testing pain killers on humans could save money and speed the arrival of new drugs
10. Patients with aberrations in two genes respond better to drugs blocking a well-known cancer pathway
11. New Diabetes Drugs Have Different Advantages, Study Says
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
More New Drugs a Bad Fit With Grapefruit, Study Finds
(Date:9/2/2014)... Sept. 2, 2014 (HealthDay News) -- Two new studies ... suggests that 6-year-olds who were breast-fed have a lower ... bottle-fed infants, while the other finds a similar trend ... the "many benefits of breast-feeding in the immediate newborn ... Hill Hospital in New York City. She was not ...
(Date:9/2/2014)... (HealthDay News) -- A leading group of oncologists has ... form of advanced breast cancer. HER2-negative breast ... target the HER2 protein, the American Society of Clinical ... Almost 80 percent of women with advanced breast ... releasing this guideline, our aim is to improve both ...
(Date:9/2/2014)... with less intensive (and expensive) practice patterns appear to ... patients unnecessary and excessive medical care, according to a ... "Growing concern about the costs and harms of medical ... avoid the provision of unnecessary care," said lead author ... Dartmouth Institute for Health Policy & Clinical Practice. ...
(Date:9/2/2014)... 02, 2014 When weather conditions are right, ... night, leaving behind a path of destruction. In fact, the ... average of 1,253 tornadoes per year. Rainbow International offers the ... a tornado strikes., , Select a safe ... in your home with no windows to stay during the ...
(Date:9/2/2014)... FL (PRWEB) September 02, 2014 Alliance ... targeting and multi-channel email marketing is pleased to announce ... market, Firearms & Freedom as well as ... properties represent more than one million concerned Americans who ... advertising. , “We are honored to continue providing ...
Breaking Medicine News(10 mins):Health News:More Evidence Breast-Feeding Lowers Child's Risk of Infections, Allergies 2Health News:New Guidelines for Treating Form of Advanced Breast Cancer 2Health News:Residency training predicts physicians' ability to practice conservatively 2Health News:Act Quickly in Case of Tornado: Rainbow International® Offers Tips on How to Be Prepared for a Tornado 2Health News:ASG Continues to Bring New Lists to Market 2Health News:ASG Continues to Bring New Lists to Market 3
... 2010 Onconova Therapeutics, Inc. is presenting new data ... summarizing several studies with the company,s radioprotectant Ex-RAD at ... (RRS), September 25-29 in Maui, Hawaii. In vivo ... significant increase in survival versus placebo-treated groups in mice ...
... place Jan. 13-16, 2011 at the Wynn Las Vegas. ... (each morning), observing differences in technique from a variety ... Lectures and plenary sessions will cover topics as bladder, ... to treat patients with benign prostate cancer. , Also ...
... CA September 27, 2010 Hoag Memorial ... for patient-specific vaccine therapy to treat metastatic melanoma. ... that patient-specific vaccines can sometimes induce durable complete ... in one particular patient who participated in the ...
... puts children with a chronic lung condition caused by ... to a study from Johns Hopkins Children,s Center published ... The researchers say their findings should prompt pediatricians ... for signs of lung disease and to discuss the ...
... By Dennis Thompson HealthDay Reporter , FRIDAY, Sept. ... feared diseases on the planet, and the second leading cause ... is slowly conquering cancer, according to an assessment of cancer ... with the U.S. Centers for Disease Control and Prevention, the ...
... You,d think that people choosing to live near to outdoor ... BMI thanks to an increase in all that healthy outdoor ... Alberta study looking at the relationship between reasons for choosing ... that,s simply not the case. In fact researchers ...
Cached Medicine News:Health News:Onconova Therapeutics presents new data demonstrating radioprotection by Ex-RAD at RRS annual meeting 2Health News:Onconova Therapeutics presents new data demonstrating radioprotection by Ex-RAD at RRS annual meeting 3Health News:Study shows patient-specific vaccines for metastatic melanoma may induce durable complete regression 2Health News:Daycare puts children with lung disease at risk for serious illness 2Health News:As Science Unlocks Secrets, Cancer Rates Fall 2Health News:As Science Unlocks Secrets, Cancer Rates Fall 3Health News:As Science Unlocks Secrets, Cancer Rates Fall 4Health News:Moving closer to outdoor recreation not a recipe for being more physically active 2
(Date:9/2/2014)... , Spanien, September 2, 2014 /PRNewswire/ ... auf dem ESC-Kongress 2014 präsentierte GARFIELD-AF-Register ... und Behandlungsergebnisse von schlaganfallgefährdeten Patienten in ... Die Daten der ... einer innovativen und unabhängigen Forschungsinitiative zur ...
(Date:9/2/2014)... 2014 Particle Sciences, the leading CDMO for ... development and manufacturing capabilities with the addition of a ... Particle Sciences, Associate Director Clinical Production, "The company has ... square footage, equipment and staff across the board, all ... has over 6000ft 2 of operating cleanroom and ...
(Date:9/2/2014)... , Sept. 2, 2014  Edison Nation Medical, ... partnership with the American Association for Respiratory Care ... respiratory care specialists. Edison Nation Medical, which brings ... business to commercialize their innovation ideas, will work ... of more than 50,000 respiratory therapists in bringing ...
Breaking Medicine Technology:Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 2Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 3Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 4Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 5Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 6Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 7Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 8Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 9Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 10Daten aus dem globalen Register zur Behandlung von Vorhofflimmern zeigen, dass antithrombotische Wirkstoffe zur Verhinderung von Schlaganfällen nicht optimal genutzt werden 11Particle Sciences Expands Drug Eluting Device Capabilities and Overall Clinical Trial Manufacturing Resources 2Edison Nation Medical and AARC Team Up To Promote Innovation in Respiratory Care 2Edison Nation Medical and AARC Team Up To Promote Innovation in Respiratory Care 3
Precision that fits in the palm of your hand and measures down to 125 microns, the Pocket Pachymeter is about 8" X 4" x 2" and really does fit in a lab coat pocket or briefcase....
15 segment Vertical Prism Bar provides 1, 2, 3, 4, 5, 6, 8, 10, 12, 14, 16, 18, 20, 25, 30 PD (Note: 30 PD is on the bar). 4448 xx Combined Horizontal and Vertical Prism Bar....
High performance capabilities in a multipurpose generator blended cut modes provide flexibility through varying degrees of hemostasis. Choose one of three preset modes. provide flexibility through va...
... Hyfrecator has been the #1 product ... electrosurgery for over 60 years. Remote control ... sterile field and decrease procedural time. Dual ... output of the Hyfrecator, the second to ...
Medicine Products: