Navigation Links
More Known About Proteins That Cause Autoimmune Diseases
Date:1/17/2012

TUESDAY, Jan. 17 (HealthDay News) -- A new study says more than 32 million people in the United States have autoantibodies, which are proteins produced in the immune system that attack the body's tissues.

Autoantibodies can cause autoimmune diseases such as rheumatoid arthritis, lupus and type 1 diabetes, researchers say.

Researchers examined blood serum samples taken from almost 4,800 people who participated in the 1994-2004 U.S. National Health and Nutrition Examination Survey. The research team was looking for the most common type of autoantibody, called antinuclear antibodies (ANA).

The overall prevalence of antinuclear antibodies was about 14 percent and was slightly higher in blacks than in whites. Frequency generally increased with age and was higher in women than in men, with the female-to-male ratio peaking at 40 to 49 years and then declining with age.

"The peak of autoimmunity in females compared to males during the 40-49 age bracket is suggestive of the effects that the hormones estrogen and progesterone might be playing on the immune system," Linda Birnbaum, director of U.S. National Institute of Environmental Health Sciences and an author on the paper, said in a news release from the NIEHS, which conducted the study.

The researchers also found that the frequency of antinuclear antibodies was lower in overweight and obese people than in those with normal weight.

"It raises the likelihood that fat tissues can secrete proteins that inhibit parts of the immune system and prevent the development of autoantibodies, but we will need to do more research to understand the role that obesity might play in the development of autoimmune diseases," Dr. Minoru Satoh, another study author and an associate professor of rheumatology and clinical immunology at the University of Florida, said in the news release.

The study was published online Jan. 11 in the journal Arthritis & Rheumatism.

"Previous estimates of ANA prevalence have varied widely and were conducted in small studies not representative of the general population," Dr. Frederick Miller, a study author and acting clinical director at NIEHS, said in the release.

"Having this large data set that is representative of the general U.S. population and includes nearly 5,000 individuals provides us with an accurate estimate of ANA and may allow new insights into the [causes] of autoimmune diseases," he noted.

The presence of autoantibodies does not necessarily mean a person will develop an autoimmune disease. Drugs, cancer, infections and other factors can also cause autoantibodies in some people.

More information

The U.S. National Institute of Arthritis and Musculoskeletal and Skin Diseases has more about autoimmune diseases.

-- Robert Preidt

SOURCE: U.S. National Institute of Environmental Health Sciences, news release, Jan. 13, 2012


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Little Known About How Autism Affects Teen Drivers: Researchers
2. NIH scientists find earliest known evidence of 1918 influenza pandemic
3. As Venus Williams Bows Out of U.S. Open, Little-Known Disease Takes Center Court
4. Bathroom Injuries a Little-Known Problem
5. Toll of Deepwater Oil Spill on Human Health Still Unknown
6. Dangerous Wandering a Lesser Known Side of Autism
7. Lesser Known Lung Diseases Can Strike Smokers, Ex-Smokers
8. Genetic Tests May Help Track Unknown Criminals by Hair Color
9. National Stroke Association survey reveals more than half of stroke survivors suffer added burden of little known neurologic condition
10. Eat safer: Novel approach detects unknown food pathogens
11. Gut microbes promote cell turnover by a well-known pathway
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
More Known About Proteins That Cause Autoimmune Diseases 
(Date:5/27/2017)... Los Angeles, California (PRWEB) , ... May 26, 2017 , ... ... Canadian senior citizens who visit a doctor for colds or respiratory issues that are ... note that excessive time pressure on doctors may be largely responsible for the problem ...
(Date:5/27/2017)... Rosa, CA (PRWEB) , ... May 27, 2017 , ... ... cause for concern, but a new study from the Osteoarthritis Initiative shows ... to developing knee osteoarthritis. Knowing this in advance may give doctors the opportunity to ...
(Date:5/26/2017)... Fairfax, VA (PRWEB) , ... May 26, 2017 ... ... is pleased to announce a new educational seminar to focus on current legislative ... Regulatory News(LEARN) seminar will begin at 1 p.m. Sunday, Sept. 10, and will ...
(Date:5/26/2017)... ... 26, 2017 , ... Boar’s Head Brand®, one of the ... Day entertaining that are sure to satisfy your guests’ flavor cravings, while adding ... cheeses featured in these refreshingly balanced recipes are packed with flavor, creating the ...
(Date:5/26/2017)... ... May 26, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House ... focusing on the Peace Agreements being discussed by President Donald Trump and the rest ... to try to speed up peace talks in the continuous battle between Israel and ...
Breaking Medicine News(10 mins):
(Date:5/8/2017)... May 8, 2017  Diplomat Pharmacy, Inc. (NYSE: DPLO)., ... ("WRB"), a health care service center company based ... WRB specializes in relationship management programs for leading pharmaceutical ... WRB will join Envoy Health ... services for manufacturers, biotech firms, and other service companies. ...
(Date:5/4/2017)... Tenn. , May 4, 2017  A ... Infection Control, Ultraviolet-C light as a ... Tru-D SmartUVC,s ability to reduce bioburden on anesthesia ... bioburden reduction on high-touch, complex medical equipment surfaces ... surgical infections. "This study further validates ...
(Date:5/4/2017)...   BioLife Solutions , Inc. (NASDAQ: ... proprietary clinical grade hypothermic storage and ... announced that the Company,s first quarter 2017 financial results ... 11, 2017, and that the Company will host a ... that afternoon. Management will provide an overview of the ...
Breaking Medicine Technology: