Navigation Links
More Kids Taking Antipsychotics for ADHD: Study
Date:8/7/2012

By Steven Reinberg
HealthDay Reporter

TUESDAY, Aug. 7 (HealthDay News) -- Use of powerful antipsychotic medications such as Abilify and Risperdal to control youngsters with attention-deficit/hyperactivity disorder (ADHD) and other behavior problems has skyrocketed in recent years, a new study finds.

Antipsychotics are approved to treat bipolar disorder, schizophrenia, other serious mental problems and irritability related to autism. But they don't have U.S. Food and Drug Administration approval for ADHD or other childhood behavior problems, and their use for this purpose is considered "off label."

"Only a small proportion of antipsychotic treatment of children (6 percent) and adolescents (13 percent) is for FDA-approved clinical indications," said lead researcher Dr. Mark Olfson, a professor of clinical psychiatry at Columbia University Medical Center in New York City.

"These national trends focus attention on the substantial and growing extent to which children diagnosed with ADHD and other disruptive behavioral disorders are being treated with antipsychotic medications," said Olfson.

The researchers found that doctor visits between 1993-1998 and 2005-2009 that involved a prescription of antipsychotic medication for children jumped sevenfold -- from 0.24 to 1.83 per 100 people. For teens, 14 to 20 years old, the rate rose from 0.78 to 3.76 per 100 people, and for adults, it just about doubled, from 3.25 to 6.18 per 100 people.

Many of the prescriptions for children were ordered by doctors who are not psychiatrists, the researchers found.

Although these drugs can deliver rapid improvement in children with severe conduct problems and aggressive behaviors, it is not clear whether they are helpful for the larger group of children with ADHD, he said. Nor has their long-term effect on children's developing brains been studied.

Olfson said most children and adolescents treated with antipsychotics are not receiving psychotherapy. "This suggests that more needs to be done to increase access and availability of psychosocial interventions," he said.

"Parent management training and cognitive problem-solving skills training are examples of effective but underused treatments for young people with disruptive behavioral problems," he said.

The study, published in the Aug. 6 online edition of the Archives of General Psychiatry, used data from the National Ambulatory Medical Care Surveys from 1993 to 2009. More than 484,000 people were included in total.

The researchers found prescriptions for antipsychotics increased for children and adults. But doctors prescribed more antipsychotics to children and adolescents (68 percent and 72 percent, respectively) than to adults (50 percent).

For children 13 and younger, the most prescribed drug was risperidone (Risperdal). Other drugs included aripiprazole (Abilify), quetiapine (Seroquel) and olanzapine (Zyprexa). Of these drugs, Abilify was most commonly prescribed to adolescents, aged 14 to 20, the study found.

All of these antipsychotics, developed since the 1990s, are considered "atypical" or second-generation antipsychotics.

For elderly patients, the FDA recently issued a Public Health Advisory about atypical antipsychotic medications after determining that death rates are higher for elderly people with dementia when taking atypical antipsychotics.

Dr. Peter Breggin, a psychiatrist from Ithaca, N.Y., and an outspoken critic of widespread antipsychotic use in children, said these drugs damage developing brains.

"We have a national catastrophe," said Breggin. "This is a situation where we have ruined the brains of millions of children."

In controlling behavior, antipsychotics act on the frontal lobes of the brain -- the same area of the brain targeted by a lobotomy, Breggin said.

"These are lobotomizing drugs," he added. "Of course, they will reduce all behavior, including irritability," he said.

Olfson's team found that most children treated with antipsychotic medications are diagnosed with ADHD, oppositional behavior and unspecified disruptive behavioral disorders.

Between 2005 and 2009, controlling "disruptive behavior" accounted for 63 percent of the reason antipsychotics were given to children and almost 34 percent for adolescents, the researchers found.

In contrast, bipolar disorder and depression were the most common reasons these drugs were prescribed to adults during that time period.

Simon Rego, director of psychology training at Montefiore Medical Center/Albert Einstein College of Medicine in New York City, said these drugs have serious side effects, including weight gain, diabetes and heart problems.

"But, perhaps even more important is the finding that a substantial majority of the child antipsychotic visits were for young people diagnosed with disruptive behavior disorders, for which there are currently no FDA-approved antipsychotic medications," he said.

Given the uncertain effects that antipsychotic medications have on cognitive (brain), social and physical development in children and adolescents, it may be necessary to reevaluate clinical practice patterns, Rego said.

Efforts to educate physicians about the safety and effectiveness of antipsychotic medications are also needed, he said.

More information

For more information on antipsychotics, visit the U.S. National Institute of Mental Health.

SOURCES: Mark Olfson, M.D., M.P.H., professor of clinical psychiatry, Columbia University, New York City; Simon A. Rego, Psy.D., director of psychology training, Montefiore Medical Center/Albert Einstein College of Medicine, New York City; Peter Breggin, M.D., psychiatrist, Ithaca, N.Y., author, Psychiatric Drug Withdrawal: A Guide for Prescribers, Therapists, Patients and their Families; Aug. 6, 2012, Archives of General Psychiatry, online


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Not taking gastroprotective drugs prescribed with anti-inflammatory medicines
2. Seniors Stop Taking Heart Drugs In Medicare Donut Hole
3. Taking Away Car Keys Can Be Tough for Older Drivers
4. Taking Anti-HIV Meds Prior to Exposure May Help Prevent Infection
5. Patients taking certolizumab pegol are twice as likely to achievE ACR20 compared to placebo
6. Young Men Taking HIV Meds May Be at Risk for Bone Loss
7. Taking the fate of stem cells in hand: RUB researchers generate immature nerve cells
8. Taking tissue regeneration beyond the state-of-the-art
9. Taking nothing at face value
10. Off-label drug use common, but patients may not know theyre taking them, Mayo finds
11. Antipsychotics Do Help Many With Schizophrenia, Study Finds
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
More Kids Taking Antipsychotics for ADHD: Study 
(Date:5/27/2016)... ... 2016 , ... This campaign aims to provide a path to improved education ... control and change. , As nearly 795,000 Americans suffering from a new or recurrent ... Plus, with an estimated 129,000 of these people dying from stroke, it’s become our ...
(Date:5/27/2016)... ... May 27, 2016 , ... Aimed at nurses and employees ... stories, courtesy of leaders in the nursing and health care industry. It also ... advocates and associations—namely Jones & Bartlett Learning. , Jones & Bartlett Learning is ...
(Date:5/26/2016)... ... May 26, 2016 , ... Despite last week’s media reports ... Yellen and company to wait until March 2017 for an interest rate increase, according ... Robinson College of Business. , “The Federal Open Market Committee (FOMC) dot charts are ...
(Date:5/26/2016)... (PRWEB) , ... May 26, 2016 , ... ... and clinical outcomes, hosted members and suppliers for its inaugural Member Conference at ... on their mission of elevating the operational health of America’s healthcare providers. , ...
(Date:5/26/2016)... Florida (PRWEB) , ... May 26, 2016 , ... ... House® Project offering a new model of care for living and healing, celebrated ... core values: Meaningful Life in a Real Home provided by Empowered Staff. , “This ...
Breaking Medicine News(10 mins):
(Date:5/27/2016)... Amarantus BioScience Holdings, Inc. ... Regenerative Medicine, Neurology and Orphan Diseases, today announced that President & ... upcoming investor conferences: SeeThru Equity MicroCap Conference   ... New York City , NY When: Tuesday, May ... Conference   Where: Grand Hyatt Hotel, 109 East 42 ...
(Date:5/26/2016)... NASHVILLE, Tenn. , May 26, 2016 ... provider of software and analytics, network solutions ... healthcare, today announced it entered into a ... leading provider of outpatient software solutions and ... surgery centers, specialty hospitals and rehabilitation clinics ...
(Date:5/25/2016)... , Germany and GERMANTOWN, ... QIAGEN N.V. (NASDAQ: QGEN ; Frankfurt Prime Standard: ... licensing and co-development agreement with Therawis Diagnostics GmbH to develop ... be to develop and market PITX2 as a marker to ... high-risk breast cancer patients. "We are pleased to ...
Breaking Medicine Technology: