Navigation Links
More Genes Implicated in Type 2 Diabetes
Date:6/27/2010

ca, revisited data from previously conducted genome-wide association studies involving more than 8,000 individuals with type 2 diabetes and almost 40,000 healthy controls. All participants were of European descent.

They then added genetic data from another 34,000 people with diabetes and close to 60,000 controls.

The genes they found were associated with well-known biological processes of diabetes, namely beta-cell function (these are the pancreatic cells that produce insulin) and insulin performance, as well as cell-cycle regulation.

An unexpected finding was that one of the genes resides on the X chromosome. "That's important because it may indicate maternal inheritance," Zonszein explained.

"X chromosome association has been rare in most complex diseases, and this is the first one identified for type 2 diabetes," McCauley explained.

Also interesting is the fact that seven of the regions are known to be involved in other diseases or human characteristics including height, certain cardiovascular risk factors, and skin and prostate cancer.

"There are independent associated signals in what we would consider to be unrelated diseases or unrelated phenotypes," McCauley stated. "This further points out that biology is complex. Genes do a lot of things. They're involved with a lot of networks."

More information

The American Diabetes Association has more on type 2 diabetes.

SOURCES: Joel Zonszein, M.D., director, Clinical Diabetes Center, Montefiore Medical Center, New York City; Jacob L. McCauley, Ph.D., assistant professor, John P. Hussman Institute for Human Genomics, University of Miami, Miller School of Medicine; June 27, 2010, Nature Genetics


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Scientists ID a protein that splices and dices genes
2. Genes May Influence Preterm Births
3. New Research Shows Genes of Pregnant Women and Their Fetuses Can Increase the Risk of Preterm Labor
4. Genes of pregnant women and their fetuses can increase the risk of preterm labor
5. NIH scientists identify maternal and fetal genes that increase preterm birth risk
6. Very Obese People May Be Missing Genes
7. Scientists map out regulatory regions of genome, hot spots for diabetes genes
8. Mutating Genes May Lead to Premature Births
9. ThermoGenesis Corp. Names Healthcare Industry Executive Craig Moore to Board of Directors
10. Genes, Diet Offer New Clues to Parkinsons Disease
11. Discovery Links Genes to Pancreatic Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
More Genes Implicated in Type 2 Diabetes
(Date:6/2/2015)... 02, 2015 Bitscape Infotech today announced ... Microsoft Worldwide Small and Midsized Cloud Solutions Award. The ... Microsoft partners for demonstrating excellence in innovation and implementation ... “This comes as no surprise to us as we ... consecutively at worldwide level by Microsoft. We will continue ...
(Date:6/2/2015)... Did you wish Ryder Weise a happy sixth birthday today? ... asking for presents, but instead a donation to the ... DC Walk. , Ryder was diagnosed with HHT in December ... to sudden and extreme bleeding throughout the body. Though ... old in the form of daily nosebleeds, fatigue and shortness ...
(Date:6/2/2015)... October 1, 2015 the transition to ICD-10 will happen ... Monday, June 1st Congressman Kevin Brady, chairman of ... Committee, and 12 members of the Committee sent a ... the administration to provide a smooth transition for local ... newest coding system for healthcare professionals to code diseases, ...
(Date:6/2/2015)... ANT Wireless, proven innovator in ultra-low power (ULP) ... products implementing the ANT+ Fitness Equipment Control (FE-C) profile: ... their bike trainer products, built to create an exciting ... FE-C device profile in its Vortex Smart and Bushido ... training software, while Kinomap has added FE-C support to ...
(Date:6/2/2015)... June 02, 2015 ZOOM+, the Portland-based ... Performance Health Insurance, announced today the opening of its ... 57 - a three-in-one complete dental exam, cleaning and ... for kids. Like all ZOOM+ services, ZOOM+Smile can be ... shouldn’t the dentist office be as inviting as your ...
Breaking Medicine News(10 mins):Health News:Bitscape Infotech recognized as finalist for 2015 Microsoft Worldwide small & midsized cloud solutions award. 2Health News:Bitscape Infotech recognized as finalist for 2015 Microsoft Worldwide small & midsized cloud solutions award. 3Health News:Six-Year-Old Walks to Bring Awareness to Genetic Disease 2Health News:HomeTown Health Launches a “100 Day Countdown” in Response to ICD-10 Survey 2Health News:HomeTown Health Launches a “100 Day Countdown” in Response to ICD-10 Survey 3Health News:HomeTown Health Launches a “100 Day Countdown” in Response to ICD-10 Survey 4Health News:First ANT FE-C Enabled Fitness Products Enter Market 2Health News:First ANT FE-C Enabled Fitness Products Enter Market 3Health News:ZOOM+ Opens Its First On-Demand ZOOM+Smile Studio and Reinvents the Dental Exam 2
... FinancingMIAMI, May 5 In the best of ... promising opportunities that arise out of the sunken ... is the unprecedented offer Lasik eye surgery and ... clientele nation-wide with their VISO Advantage Program.Attaining blade-free ...
... accessory adds a fun, playful pop of whimsy to ... pendants support disabled artists seeking financial independenceSANTA CLARA, Calif., ... Studios ( www.AOPStudios.com ), the only art brand exclusively ... announced it has finalized a licensing agreement with ...
... Systems, the leading provider of information solutions for ... with AstraZeneca. AstraZeneca plans to expand the ... discovery programs to gain deeper domain knowledge of ... AstraZeneca researchers plan to leverage the powerful analysis ...
... It,s official...Curamin is the natural products industry,s ... the number-one pain-relieving product, is slated to receive ... Retailer magazine in its upcoming June issue. ... products based on a nationwide survey of health ...
... for healthcare professionals to perform full "Google" like searches on their ... ... May 5, 2009 -- Scribe Healthcare Technologies, Inc. ( http://www.scribe.com ), ... to conduct full "Google" like searches for patients with H1N1 Flu ...
... May 5 Increased public and private ... of medical insurance coverage and continued foreign ... growth within the Kenyan healthcare industry. The ... continued expansion as the government boosts the ...
Cached Medicine News:Health News:Financial Advantage in Plummeting Economy: Lasik Eye Surgery Provides More Than the Advantage of Clear Vision 2Health News:Playing with Fashion: New 'Phenominoes' Pendants Feature Blind Artists' Phenomenal Artwork on Real Dominoes 2Health News:Playing with Fashion: New 'Phenominoes' Pendants Feature Blind Artists' Phenomenal Artwork on Real Dominoes 3Health News:Playing with Fashion: New 'Phenominoes' Pendants Feature Blind Artists' Phenomenal Artwork on Real Dominoes 4Health News:Playing with Fashion: New 'Phenominoes' Pendants Feature Blind Artists' Phenomenal Artwork on Real Dominoes 5Health News:Ingenuity Systems Announces Multi-Year Deal With AstraZeneca 2Health News:Ingenuity Systems Announces Multi-Year Deal With AstraZeneca 3Health News:Curamin Voted Best New Natural Remedy in the Country 2Health News:Dictation, Transcription Workflow and Document Management Platform Aids Physicians In Searching For Swine Flu Symptoms 2Health News:Higher Outlays and Improved Regulatory Enforcement Create Opportunities in the Kenyan Healthcare Industry, Reveals Frost & Sullivan 2Health News:Higher Outlays and Improved Regulatory Enforcement Create Opportunities in the Kenyan Healthcare Industry, Reveals Frost & Sullivan 3
(Date:6/2/2015)... , June 2, 2015 The Canadian Society for ... specific tests, treatments or procedures that are commonly ... as part of Choosing Wisely Canada.  The list ... support conversations between patients and physicians about what ... Society for Vascular Surgery,s list identified the following ...
(Date:6/2/2015)... Research and Markets ( http://www.researchandmarkets.com/research/5tzcx6/specialty_enzymes ) has ... Global Strategic Business Report" report to their offering. ... following End-Use Applications: Pharmaceutical & Diagnostics, Research/ Biotechnology, and ... US, Canada , Japan ... Asia-Pacific , Latin America , ...
(Date:6/2/2015)... PITTSBURGH , June 2, 2015 ... technology (HIT) consulting firm, today announced the celebration ... organizations served throughout the U.S., since its inception ... for a skillful workforce in the healthcare technology ... resources with a company-wide dedication to facilitating clients, ...
Breaking Medicine Technology:As part of the Choosing Wisely Canada campaign the Canadian Society for Vascular Surgery releases list of commonly used tests and treatments to question 2As part of the Choosing Wisely Canada campaign the Canadian Society for Vascular Surgery releases list of commonly used tests and treatments to question 3As part of the Choosing Wisely Canada campaign the Canadian Society for Vascular Surgery releases list of commonly used tests and treatments to question 4Specialty Enzymes - Global Strategic Business Report 2015: Indispensable to the Pharmaceutical Industry 2Stoltenberg Consulting celebrates 20 years of healthcare IT consulting service 2Stoltenberg Consulting celebrates 20 years of healthcare IT consulting service 3
... March 7, 2012   Leading events organiser UBM ... announced that CPhI Japan will return to its traditional March ... held on a smaller scale in Osaka, Japan to accommodate ... to stabilize, Tokyo will once again play host to CPhI ...
... 7, 2012  ThermoGenesis Corp. (NASDAQ: KOOL ) a ... store adult stem cells, said today that it will be ... Stock Conference on Wednesday, March 14. The presentation ... begin at 10:30 a.m., Pacific Daylight Time (1:30 p.m., Eastern ...
Cached Medicine Technology:CPhI Japan Returns to Tokyo for 2012 2CPhI Japan Returns to Tokyo for 2012 3
Standard 20x long working distance objectives for greater magnifications of your microtools....
... An economical laboratory tissue culture microscope, the ... expand their applications. Olympus has taken the ... CKX41. Fluorescence can be used with an ... can be carried out on the CKX41 ...
... Eclipse TE2000S is an advanced ... research. It's exclusive CFI60 optical ... high numerical aperatures and longer ... inverted microscope to take full ...
... new Eclipse TS-100 is an innovative ... high quality tool complements any research ... CFI60 optics offer brilliant, sharp ... superb optical performance with high resolution ...
Medicine Products: