Navigation Links
More Evidence of Danger From Heart Surgery Drug
Date:2/20/2008

Anti-bleeding agent Trasylol tied to increased death, complications, studies find

WEDNESDAY, Feb. 20 HealthDay News) -- Two new studies confirm an increased incidence of death and kidney damage among people given Trasylol (aprotinin), a drug used to reduce bleeding during coronary artery bypass surgeries.

The studies suggest the drug raises patients' risks over both the short- and long-term.

Trasylol's German maker, Bayer AG, suspended marketing in the United States last November after preliminary results of a Canadian trial revealed problems with the medication.

"There continues to be an association between aprotinin and higher death rates and kidney damage," said Dr. Andrew Shaw, an associate professor of anesthesiology at Duke University and the lead author of one of the reports in the Feb. 21 issue of the New England Journal of Medicine.

The study he led looked at more than 10,000 people who underwent coronary artery bypass surgery. The death rate was 32 percent higher among the 1,343 people who got Trasylol as compared to the 2,029 who received no medication to limit their bleeding. The mortality rate for those taking Trasylol was also 27 percent higher than those given aminocaproic acid, a different medication used to limit bleeding.

One important facet of the study is that the follow-up period was as long as 10 years, Shaw said. Trasylol was put on the market in the United States in 1993.

The study also confirmed the incidence of kidney damage by precise measurements of serum creatinine, a kidney-related protein, Shaw said. "There does appear to be an association between continued use of aprotinin and reduced kidney function," he said.

The second study, led by physicians at Harvard Medical School and Brigham and Women's Hospital, used data on more than 78,000 coronary bypass surgery cases, comparing results when either Trasylol or aminocaproic acid was used.'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3

Related medicine news :

1. Jefferson researchers uncover new evidence of prolactins possible role in breast cancer
2. No strong evidence linking amateur boxing with long-term brain injury
3. AHRQ Announces Next Phase of Its Evidence-Based Practice Center Program
4. Vanderbilt Medical Center chosen as Evidence-based Practice Center
5. Little Evidence Silicone Breast Implants Harm Health
6. Consumers Should Demand Evidence, Not Guesswork, On Meat-Cancer Links
7. U of M study: Medicare lacks tools, incentives to enforce evidence-based coverage policies
8. New Study Provides Scientific Evidence That DermaLastyl Face Cream Reduces Wrinkles
9. Scientific evidence of the significant anti-cancer effect of milk thistle
10. Defining the Value of Medicine in an Evidence-Based Healthcare Marketplace
11. UC Davis researchers find evidence of mature heart cell potential in embryonic stem cells
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
More Evidence of Danger From Heart Surgery Drug
(Date:12/26/2014)... 2014 Parker & Sons, Inc. ... in heating, cooling and plumbing contractor services throughout ... services in 2014 with regard to air-conditioning systems. ... is known for its incredibly hot summers. Working ... intricacies and details of a wide variety of ...
(Date:12/25/2014)... 2014 The click strand ... strength and durability. Today, the business announces a ... valid until Jan. 30, 2015. , Click strand ... hardwood. BambooFlooringChina.com is a well-known brand in the ... to find a reliable bamboo flooring supplier. , ...
(Date:12/25/2014)... 2014 Product liability lawsuits filed in ... ( http://www.consumerinjurylawyers.com/DePuy/ ) continue to move forward in federal ... issued in the U.S. District Court, Northern District of ... open conference on January 7, 2015, at the Paul ... West Palm Beach, Florida. The Conference is scheduled to ...
(Date:12/25/2014)... Recently, Dylan Queen, a famous online company supplying ... of discounted prom dresses, most of which are priced ... the company, the promotion is valid until Jan. 22, ... the UK market. , The prom dresses in this ... styles: A-line strapless, empire strapless chiffon, one shoulder, floor-length, ...
(Date:12/25/2014)... sells many bamboo products and the business is famous ... announces big discounts on its bamboo mats , which ... the world’s leader in bamboo flooring. According to the ... 2015. , The bamboo mats are made from well-treated ... the bamboo strips for the mats are boiled and ...
Breaking Medicine News(10 mins):Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 2Health News:Parker & Sons Announces Record Demand For 24 Hour Emergency Services In 2014 With Regard To Air-Conditioning Systems 3Health News:BambooFlooringChina.com: click strand woven bamboo flooring promotion valid until Jan. 30, 2015. 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 2Health News:Federal Court Overseeing DePuy ASR Hip Lawsuit Set to Convene Conference in January, Bernstein Liebhard LLP Reports 3Health News:Dylan Queen: Cheap Prom Dresses for the UK Market 2Health News:Various Styles of Bamboo Mats in Many Colors from BambooFlooringChina.com 2
... Tickets to Private Concert through Online SweepstakesPARSIPPANY, N.J., March ... consumers the opportunity to attend a private Wynonna Judd ... on July 11th at the Country Music Hall of ... brand,s spokesperson, in an intimate setting while she performs ...
... test, study finds , , THURSDAY, March 12 (HealthDay ... for testing athletes, because current tests ignore important ... Testosterone and other hormones that increase testosterone levels ... widely used in sports, according to the World ...
... Company (NYSE Alternext: FHC) - today announced ... its FC2 Female Condom(TM), increasing its annualized FC2 ... to approximately 75-80 million units. Currently, The ... FC2, on four production lines in Malaysia. The ...
... PLC Systems Inc. (OTC Bulletin Board: PLCSF), a company ... today reported financial results for the three and twelve ... total revenues were $1,254,000, slightly higher than the $1,248,000 ... loss for the fourth quarter of 2008 was $222,000, ...
... Provide Tips to Help Prevent Vision Loss as Glaucoma ... 12 On the second annual World Glaucoma Day ... to help educate patients diagnosed with glaucoma and those ... is a worldwide epidemiological challenge affecting approximately four percent ...
... Industry leaders an aggressive, driving force in epidemic ... International, an organization that has compelled corporations from ... is now taking on the fast food industry.In ... to shortened life spans and elevated cancer risk, ...
Cached Medicine News:Health News:Wynonna Judd and alli Host Private Concert in Nashville 2Health News:European Researchers Call for New Doping Standards 2Health News:The Female Health Company to Expand Manufacturing Capacity for FC2 Female Condom By 150% 2Health News:The Female Health Company to Expand Manufacturing Capacity for FC2 Female Condom By 150% 3Health News:PLC Systems Reports Fourth Quarter 2008 Results 2Health News:PLC Systems Reports Fourth Quarter 2008 Results 3Health News:PLC Systems Reports Fourth Quarter 2008 Results 4Health News:PLC Systems Reports Fourth Quarter 2008 Results 5Health News:On World Glaucoma Day, Keep an Eye on the Future 2Health News:On World Glaucoma Day, Keep an Eye on the Future 3Health News:On World Glaucoma Day, Keep an Eye on the Future 4Health News:On World Glaucoma Day, Keep an Eye on the Future 5Health News:On World Glaucoma Day, Keep an Eye on the Future 6Health News:Fast Food Giants Urged to Value [the] Meal 2Health News:Fast Food Giants Urged to Value [the] Meal 3
(Date:12/24/2014)... LifeScienceIndustryResearch.com adds 2014 ... Industry of 178 pages providing 10 company ... The 2014 Market Research Report ... professional and deep research report on Global ... report introduces Disposable Syringe basic information including ...
(Date:12/24/2014)... , Dec. 23, 2014  Lockton Dunning ... of Lockton Companies, announced the addition of Vice ... will join Lockton Dunning,s Pharmacy Consulting team, Excelsior ... of relevant industry experience to the position.  Most ... Market Sales at Diplomat Specialty Pharmacy, where she ...
(Date:12/24/2014)... 23, 2014 In response to urgent requests from the ... Sierra Leone , Direct Relief delivered two 10-bed ... the treatment of local health workers who contract Ebola while ... Ebola care center was constructed for foreign health care workers ... available for local Sierra Leonean health workers. With ...
Breaking Medicine Technology:World Disposable Syringe Market 2014 Report: China and Regional Analysis 2World Disposable Syringe Market 2014 Report: China and Regional Analysis 3World Disposable Syringe Market 2014 Report: China and Regional Analysis 4World Disposable Syringe Market 2014 Report: China and Regional Analysis 5Kim Foerster Joins Lockton Companies 2First Ebola Treatment Unit for Local Health Workers Arrives in Sierra Leone 2
... 5, 2011 ForteBio®, Inc., a leading supplier of ... pharmaceutical products, today announced the launch of BLItz™, a ... the first time – to conduct label-free analyses of ... their lab bench. The new platform was unveiled today ...
... Dec. 5, 2011 A new national survey shows ... and the variety of drugs and drugstores they provide, the ... survey also found that consumers care most about holding down ... drugstores but raise prescription drug costs. "While ...
Cached Medicine Technology:ForteBio Introduces BLItz™, a Revolutionary, Micro-volume Label-free Analysis Platform for Personal Assays 2ForteBio Introduces BLItz™, a Revolutionary, Micro-volume Label-free Analysis Platform for Personal Assays 3New Consumer Survey Finds Overwhelming Satisfaction with Pharmacy Benefits 2
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: