Navigation Links
More Drug Trials Needed for Conditions Affecting Kids: Review
Date:7/25/2012

By Carina Storrs
HealthDay Reporter

WEDNESDAY, July 25 (HealthDay News) -- A new review finds that while children account for almost 60 percent of those with five common medical conditions, only 12 percent of clinical trials of drugs for those conditions examined their effects on pediatric patients.

Yet, the review authors noted, previous research has shown that off-label drugs, where the medicine has only been approved for adult use by the U.S. Food and Drug Administration, make up as much as 79 percent of the medications given to children in hospitals and up to 56 percent of drugs prescribed for kids in doctors' offices.

"We think this contrast is striking, and speaks to the under-representation of research on kids," said review author Dr. Florence Bourgeois, an assistant professor of pediatrics at Boston Children's Hospital and Harvard Medical School in Boston. "Understandably, whenever we see an adverse event the concern is, 'Could these drugs really be dangerous?' and we are left wondering."

The results were released online July 23 in advance of publication in the August print issue of the journal Pediatrics.

The FDA requires that clinical trials demonstrate a drug's safety and effectiveness for a condition before it approves the drug to treat that condition, but many drugs are only tested in adults. As a result, physicians are often left to rely on trial-and-error to decide how to use drugs off-label in children, the review noted.

Bourgeois and her team found that, while just over 21 percent of people in high-income countries who are afflicted by conditions such as depression, asthma, migraines, schizophrenia and bipolar disorder are children and adolescents, less than 10 percent of clinical trials studying these conditions included patients under the age of 18.

The gap was even wider for developing countries, where children and adolescents bear nearly 62 percent of the disease bu
'/>"/>

Copyright©2012 ScoutNews,LLC.
All rights reserved  

Page: 1 2 3 4

Related medicine news :

1. Preclinical data support ongoing clinical trials testing IDO inhibitors as a treatment for cancer
2. Access to clinical trials drives dramatic increases in survival from childhood cancer
3. Psychoeducational intervention changes patient attitudes on clinical trials participation
4. Canada should significantly increase its funding of randomized clinical trials
5. Experts call for clinical trials to test non-skeletal benefits of vitamin D
6. Analysis Finds Clinical Trials Often Small, of Poor Quality
7. Many Teens With High Blood Pressure Dont Get Needed Tests
8. Study suggests changes in rotator cuff surgery rehabilitation needed
9. New technique could reduce number of animals needed to test chemical safety
10. Changes needed for oft-ignored prescription warning labels
11. More Vigilance Needed to Protect Kids With Food Allergies
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
More Drug Trials Needed for Conditions Affecting Kids: Review
(Date:5/3/2015)... HealthPostures, a pioneering ergonomics company that ... the , May 5 - 7, 2015 Minnesota Safety ... the conference include its bestselling TaskMate sit stand solutions. ... 6100 TaskMate Executive. Features of the 6100 TaskMate Executive ... extended platform work surface and supply holders. Weighing 50 ...
(Date:5/2/2015)... Viejo, CA (PRWEB) May 02, 2015 ProText ... exclusively for use in Final Cut Pro X. ProText ... for use in Final Cut Pro X . ... single keyframe with Pixel Film Studios' ProText Kinetic 2. , ... Start by staggering two ProText Kinetic presets in the ...
(Date:5/2/2015)... May 02, 2015 Kare Visits LLC. launched ... for busy caregivers. Kare Visits offers relief for caregivers ... living facilities. According to the Caregiver Action Network, ... average of 20 hours a week caring for an elderly ... cost to hire a nurse, a caregiver is now empowered ...
(Date:5/1/2015)... Caicos Islands, BWI (PRWEB) May 02, 2015 ... website! It is http://www.thevenetiangracebay.com , and it ... it incorporates the stunning white and attractive turquoise hues ... study of Google, sixty seven percent of leisure travelers ... study showed that smartphones were used in the planning ...
(Date:5/1/2015)... (PRWEB) May 01, 2015 TROY Healthcare ... Cerner Southeast Regional User Group (RUG) Conference in Atlanta, ... Southeast Regional User Group Conference provides a forum for ... who support all aspects of electronic medical record operations, ... Cerner software applications. , In addition to sponsoring the ...
Breaking Medicine News(10 mins):Health News:HealthPostures to Appear at the Minnesota Safety and Health Conference 2Health News:HealthPostures to Appear at the Minnesota Safety and Health Conference 3Health News:Pixel Film Studios Announced the Release of Protext Kinetic 2 for FPCX. 2Health News:Chicagoan Seeks to Transform Industry by Launching an Innovative Elderly Care Solution 2Health News:Turks and Caicos Resort, The Venetian on Grace Bay, Launches New Web Presence 2Health News:TROY Healthcare to Exhibit at the Cerner Southeast Regional User Group Conference 2Health News:TROY Healthcare to Exhibit at the Cerner Southeast Regional User Group Conference 3
... own natural alarm clocks which can be set subconsciously just ... conducted by scientists at the University of Lubeck in Germany ... them to anticipate the "stress" of getting up at different ... of the power of thought when it comes to controlling ...
... demanding - or who do shift work - could ... in the US showed that this heavy work was ... babies. ,Jobs which involved long periods of ... significantly linked with premature birth. Physically demanding work was ...
... is implanted permanently in the eye is safe and effective ... alternative for laser operations that correct nearsightedness by reshaping the ... Allan Vukich of the University of Wisconsin School of Medicine ... the results of a multicenter trial of patients who had ...
... serious morning sickness if they are pregnant with a girl, ... Norway between 1977 and 1985 showed there was a greater ... female child. ,Though there were more births of ... of mothers-to-be of girls being admitted to hospital suffering from ...
... and aspirin are equally effective in stroke prevention in the ... stopping platelets from clumping together, while warfarin acts on the ... help prevent blood clots in the brain that lead to ... more effective at preventing stroke, but causes more side effects ...
... self-contained artificial heart suffered bleeding in his brain in the ... latest setback caused swelling and made the patient, Robert Tools, ... said. // ,Robert Tools received the AbioCor mechanical ... the time, he was so ill he had been given ...
Cached Medicine News:Health News:The alarm clock in you 2
(Date:5/1/2015)... , May 1, 2015  Legendary actor and director ... a new PBAFacts campaign designed to educate and encourage ... more about Pseudobulbar Affect (PBA) and to speak with ... an actor has the ability to cry and laugh ... of control experienced by people living with PBA episodes. ...
(Date:5/1/2015)... 2015  Misonix, Inc. (NASDAQ: MSON ), ... and markets innovative therapeutic ultrasonic products for spine ... laparoscopic surgery and other surgical applications, announced today ... third quarter fiscal year 2015 on Thursday, May ... call that same day, Thursday, May 7, 2015, ...
(Date:4/30/2015)... WOODBRIDGE, ON , April 30, 2015 /PRNewswire/ ... a specialty pharmaceutical company with a focus on ... health, announced its operational highlights and financial results ...  All dollar amounts referenced herein are in Canadian ... in 2014 have been significant, with the right ...
Breaking Medicine Technology:Danny Glover Joins PBA Facts Campaign, to Educate and Build Awareness of Pseudobulbar Affect (PBA), a Little Known but Widespread Neurologic Condition 2Danny Glover Joins PBA Facts Campaign, to Educate and Build Awareness of Pseudobulbar Affect (PBA), a Little Known but Widespread Neurologic Condition 3Misonix, Inc. To Report Third Quarter Fiscal Year 2015 Financial Results On Thursday, May 7, 2015 2Pivotal Therapeutics Announces 2014 Financial Results 2Pivotal Therapeutics Announces 2014 Financial Results 3Pivotal Therapeutics Announces 2014 Financial Results 4Pivotal Therapeutics Announces 2014 Financial Results 5Pivotal Therapeutics Announces 2014 Financial Results 6
... MARINO, Calif., June 14, 2011 Viral Genetics, ... to a clinical-stage company. The Company,s two lead ... Metabolic Disruption (MDT) compounds for drug-resistant cancers -- ... or investigator-initiated Investigational New Drug (IND) pathways. An ...
... BSI Group America Inc. (BSI), a leading ... solutions, is pleased to introduce Entropy Software for ... quality management software solution to assist organizations to ... reporting, and improved quality and compliance assurance. Designed ...
Cached Medicine Technology:Viral Genetics Updates HIV/AIDS and Drug Resistant Cancer Research Programs 2Viral Genetics Updates HIV/AIDS and Drug Resistant Cancer Research Programs 3Viral Genetics Updates HIV/AIDS and Drug Resistant Cancer Research Programs 4BSI Introduces Entropy® Software for Healthcare Product Manufacturers 2BSI Introduces Entropy® Software for Healthcare Product Manufacturers 3
... Physician-office® is an internet ... (Solo practice, group practice ... complete their normal duties ... is a front office ...
... is a modular, Electronic Medical Record (EMR) system ... create a patient chart. ChartMaker is an ... M compliant patient notes, medical reports, letters, and ... ChartMaker is designed to be installed in a ...
... original EMR companies, with a wealth and ... With over a decade of clinical and ... design, corporate level training and support, enables ... medical practice to EMR. The unparalleled HL7 ...
... is dedicated to serving the needs ... ultimate tool to,run a better orthopaedic ... records software.,AcerMed's Orthopaedic-Edition EMR software has ... surgeons across the country resulting in ...
Medicine Products: