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More Assisted Reproduction, But Fewer Multiple Births
Date:5/28/2009

crease in the number of embryos transferred, pregnancy and delivery rates have increased for both frozen and fresh embryo cycles. In 2002, more than 601,250 ART cycles resulted in delivery rates per aspiration (attempt at egg retrieval) of 22 percent for IVF, 21 percent for ICSI and 15 percent for frozen embryo transfer. In 2000, those rates were 19 percent, 20 percent and 12 percent, respectively.
  • When fresh embryo and frozen embryo cycles were combined, the global cumulative delivery rate per aspiration was 26 percent.
  • There was a decrease in transfers of multiple embryos, which resulted in a small decline in multiple births. The percentage of transfers of four or more embryos decreased from 15.4 percent in 2000 to 13.7 percent in 2002. The percentage of twin pregnancies decreased from 26.5 percent to 25.7 percent, and the rate of triplet pregnancies decreased from 2.9 percent to 2.5 percent.
  • A 47 percent increase in the proportion of frozen embryo transfer cycles was notable because it led to improved cumulative pregnancy and delivery rates and decreased the number of multiple embryo transfers and multiple births, de Mouzon said.

    "Our report shows that delivery rates per aspiration increased in 2002 even though the average number of embryos transferred was reduced. For example, in Australia, where a mean average of 1.8 embryos were transferred, the delivery rate per aspiration was 19.5 percent for fresh cycles and 29.4 percent for fresh and frozen cycles together. This should encourage countries to implement embryo transfer policies that reduce the risk of multiple births," he said.

    The study was published online May 28 in the journal Human Reproduction.

    More information

    The U.S. Centers for Disease Control and Prevention has more about ART.



    -- Robert Preidt
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