Navigation Links
More African-Americans burdened by osteoarthritis in multiple large joints
Date:10/20/2011

New research suggests African Americans have a higher burden of multiple, large-joint osteoarthritis (OA), and may not be recognized based on the current definition of "generalized OA." African Americans were also more likely to have knee OA, but less likely to be affected by hand OA than Caucasians according to the findings reported today in Arthritis & Rheumatism, a peer-reviewed journal of the American College of Rheumatology (ACR).

OA is the most common type of arthritis and typically affects multiple joints. The National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) estimates that more than 27 million adults, 25 years of age and older, are burdened by OA. With the percentage of those affected by OA increasing as the population ages, NIAMS projects that 67 million individuals will have doctor-diagnosed arthritis by 2030. While previous studies have investigated radiographic or symptomatic OA patterns using combinations of joint sites, research of multi-joint involvement has mainly been limited to Caucasian women.

For the current study, part of the Johnston County Osteoarthritis Project, Dr. Amanda Nelson from the University of North Carolina at Chapel Hill-UNC Rheumatology/Thurston Arthritis Research Center and colleagues, analyzed radiographic data for the hands, knee (tibofemoral [TFJ] and patellofemoral joints), hips and spine (lumbosacral) in African American and Caucasian men and women who were 45 years of age and older. The team identified 16 mutually exclusive hand OA phenotypes in 2083 participants and 32 whole-body phenotypes in 1419 individuals. Information on age, gender, race and body mass index (BMI) was also collected through questionnaires and clinical examination.

After adjusting for age, gender and BMI, analysis showed that African Americans had significantly less frequent OA in finger tip joints (distal interphalangeal), alone and with other hand joint sites compared to Caucasians. African Americans compared with Caucasians were twice as likely to have knee (TFJ) OA and had 77% greater odds of knee and spine OA together. Frequencies of OA in hand joint sites other than distal interphalangeal joints were comparable between both races.

Study participants had a mean age of more than 65 years, with a mean BMI categorizing them as obese. One third of participants were male and two thirds were Caucasian. Overall 42% of the study subjects had knee OA, 36% had hip OA and 32% OA of the hand. Spine OA was most common, occurring in 62% of participants. "Racial differences in OA phenotypes were more significant than gender disparity," concluded Dr. Nelson. "Our findings suggest a substantial health burden of large-joint OA, particularly hip and spine, among African Americans and further studies that address this concern are warranted."


'/>"/>

Contact: Dawn Peters
healthnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

Related medicine news :

1. African-Americans more likely to donate kidney to family member
2. Research examines approaches to treating substance abuse among African-Americans
3. New data-based strategies and treatment models can improve diabetes care for older African-Americans
4. Genetic map of African-Americans to aid study of diseases, human evolution
5. More oxygen in eyes of African-Americans may help explain glaucoma risk
6. CT angiography improves detection of heart disease in African-Americans
7. Why disparities in dental care persist for African-Americans even when they have insurance coverage
8. Low vitamin D levels seen as multiple sclerosis risk for African-Americans, UCSF study finds
9. African-Americans with SLE more responsive to flu vaccine than patients of European descent
10. Race gap narrows for some cancers in African-Americans; continues to increase for others
11. Storytelling may help control blood pressure in African-Americans
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/6/2016)... ... , ... With the FCPX LUT: Summer pack from Pixel Film ... LUT is a Lookup Table that contains a mathematical formula for modifying an image. ... By manipulating each pixel, LUT's can change each color range differently, it gives the ...
(Date:2/6/2016)... ... February 06, 2016 , ... Research has ... helps to reduce the frequency and level of relapse. , At ... Identity and Purpose,” will explore the critical tasks of the recovery phase and ...
(Date:2/5/2016)... Bethpage, NY (PRWEB) , ... February 05, 2016 , ... ... florist-quality long-stem roses in a variety of colors, assortments and packaging. This staple for ... at any King Kullen location. , For Valentine’s Day, not only are long-stem ...
(Date:2/5/2016)... & Salt Lake City, UT (PRWEB) , ... February 05, 2016 ... ... of Activz Whole-Food Nutrition , announced that the much-anticipated feature with author Jahnavi ... New Really Cool Humans Amateur TV Network. , Each week, on his weekly Whole-Food ...
(Date:2/5/2016)... ... February 05, 2016 , ... The event is being ... Block Event Center in Minneapolis, Minn. Triumph Over Parkinson’s will fund nearly $100,000 for ... of Schneiderman’s Furniture, lives with Parkinson’s disease and is the architect of this informative ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... Feb. 5, 2016 Aethlon Medical, Inc. (Nasdaq: ... and CEO, will be presenting at Source Capital Group,s 2016 ... NY at 2:15 p.m. ET on Wednesday, February ... Panel discussion taking place at 3:15 p.m. ET. ... one hour after the conclusion of the live event. The ...
(Date:2/5/2016)... -- Dehaier Medical Systems Ltd. (Nasdaq: DHRM ... markets and sells medical devices and wearable sleep ... and international markets, today announced its corporate and ... Company,s resources to develop its mobile health business, ... more on its major businesses. As of this ...
(Date:2/5/2016)...  Henry Schein, Inc. (NASDAQ: HSIC ), the world,s ... office-based dental, animal health and medical practitioners, announced today ... a majority ownership interest in Dental Cremer S.A., a ... Brazil . --> ... the dental distribution business of Cremer S.A. With 2015 ...
Breaking Medicine Technology: