Navigation Links
Monogram Biosciences Announces Immediate Availability of Enhanced Sensitivity Trofile(TM) HIV Tropism Assay
Date:6/5/2008

ion, such as the enhanced sensitivity of Trofile, which will give physicians important information when deciding whether or not to incorporate a CCR5 antagonist like Selzentry into a patient's treatment regimen," said Dr. Howard Mayer, MD, Executive Director, Pfizer Development Team Leader for HIV/AIDS. Pfizer and Monogram have a collaboration agreement for commercialization of Trofile outside of the U.S.

"Detection of CXCR4-using minority variants has been shown as an important indicator of CCR5 antagonist treatment success and Trofile is the only clinically validated assay to identify co-receptor tropism, a step the FDA and EMEA has determined is critical in selecting patients for treatment with a CCR5 antagonist," said Monogram CEO William Young. "Trofile is the gold standard in tropism testing and the enhanced sensitivity version now available sets a new standard for performance so that the thousands of physicians who rely on our assay can better direct patient selection."

Trofile examines the complete gp160 coding region of the HIV-1 envelope protein, ensuring that all of the determinants of tropism are tested. In a retrospective analysis reported at the recent Conference on Retroviruses and Opportunistic Infections, the enhanced assay improved patient selection by identifying more cases of dual / mixed virus, and more accurately predicted virologic outcomes. In addition to providing patient selection for Selzentry's pivotal trials, Trofile has been used for patient selection and monitoring in all Phase II and III clinical trials of co-receptor antagonists.

About Trofile

Trofile is a clinically validated patient selection tropism assay that determines whether a patient is infected with a strain of HIV that uses either the CCR5 co-receptor, the CXCR4 co-receptor, or a combination of CCR5 and CXCR4 to enter cells. The use of CCR5, CXCR4 or both co-receptors defines the "tropism" of the virus strain. Trofile amplifies the envelope gene
'/>"/>

SOURCE Monogram Biosciences, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine news :

1. Monogram Announces First Medicare Payment for Trofile(TM)
2. Monogram Biosciences to Present at The Lazard Capital Markets Fourth Annual Healthcare Conference
3. Sangamo BioSciences to Present at the ThinkEquity Partners Growth Conference
4. Akers Biosciences, Inc. ABI or the Company Receipt of Further United States Military Contracts
5. Pressure BioSciences to Present at the Rodman & Renshaw BioFin 9th Annual Healthcare Conference in New York City on November 5th
6. Neurocrine Biosciences to Present at the CIBC World Markets 18th Annual Healthcare Conference
7. Pressure BioSciences, Inc. to Discuss Third Quarter Financial Results and Provide Business Update
8. Anaptys Biosciences Raises Over $33 Million in Series B Financing
9. YM BIOSCIENCES REPORTS FIRST QUARTER 2008 OPERATIONAL AND FINANCIAL RESULTS
10. Pressure BioSciences, Inc. Reports Third Quarter 2007 Financial Results and Provides Business Update
11. Schering-Plough Receives Clearance From U.S. Federal Trade Commission for Planned Acquisition of Organon Biosciences N.V.
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... (PRWEB) January 22, 2015 Padre Murphy's and ... supporter of Pro Player Health Alliance (PPHA). The ... Murphy's in getting everyone, including NFL greats, treated for obstructive ... the leading groups supporting the cause in the valley. The ...
(Date:1/22/2015)... 23, 2015 Angelweddingdress is a famous wedding ... its customers to follow it on Facebook, Twitter, and Pinterest. ... Day gift. Angelweddingdress draws a lottery every week. , Moreover, ... Feb. 28, 2015. Click Angelweddingdress homepage for more ...
(Date:1/22/2015)... 22, 2015 The federal court overseeing thousands ... District Court, Southern District of West Virginia has upheld a ... proceeding’s first bellwether trial. In an Order dated January 21st, ... after finding that C.R. Bard had not proven a miscarriage ...
(Date:1/22/2015)... January 22, 2015 Thousand of GranuFlo ... Care recalled its GranuFlo and NaturaLyte dialysis concentrates continue ... in U.S. District Court, District of Massachusetts, Bernstein Liebhard ... the Court has remanded a case filed by the ...
(Date:1/22/2015)... 22, 2015 Carinsurancesavings.biz has released a new ... and dismemberment insurance . , Purchasing an accidental death ... very advantageous. This type of rider provides benefits if the ... be considered a lesser form of life insurance. , ...
Breaking Medicine News(10 mins):Health News:Padre Murphy's Holds NFL Retired Players Association Party Star Studded Event With Bud Light and Pro Player Health Alliance Sponsoring 2Health News:Padre Murphy's Holds NFL Retired Players Association Party Star Studded Event With Bud Light and Pro Player Health Alliance Sponsoring 3Health News:Angelweddingdress Invites Its Customers To Follow It On Facebook, Twitter, And Pinterest 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 3Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 4Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 2Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 3Health News:Court Overseeing Federal GranuFlo Lawsuits Remands Louisiana Claim Back to State Court, Bernstein Liebhard LLP Reports 4Health News:Accidental Death and Dismemberment Insurance Can Be Purchased at Low Prices Online 2
... KENNETT SQUARE, Pa., Aug. 19 Genesis HealthCare ... today announced that 16 of its Centers have been recognized ... presented by the American Health Care Association and National Center ... living centers from across the nation applied for the quality ...
... Sometimes that means trying some risky behaviors. ... cocaine, will be studied in their adolescent years. Researchers ... using drugs, having sex or engaging in delinquent behaviors, and ... The study will also closely follow the cognitive ...
... University of Leicester has revealed new ways to spot ... prestigious British Medical Journal , Santiago Moreno and ... the reporting of clinical trials which potentially form the ... show what mathematical adjustments can be made to remove ...
... chronic liver disease characterized by progressive inflammation and destruction ... usually leading to biliary cirrhosis, portal hypertension and liver ... a common cause of adult cholestatic liver diseases and ... in U.S. adults. At least 70% of PSC ...
... , Editorial is a Call to ... Research indicates that the social stigma that surrounds lesbian, gay, bisexual, ... as substance use, risky sexual behaviors, eating disorders, suicidal ideation, and victimization. ... Health calls on clinicians and health researchers to lead the charge ...
... CARDIFF, Calif., Aug.19 Rapi d ... plans to provide services to the medical cannabis industry. With ... the state of California, Rapid Fire Marketing has entered the ... to this newly-emerged industry, which includes medical doctors and cannabis ...
Cached Medicine News:Health News:Sixteen Genesis HealthCare Centers Receive Prestigious Award for Continuous Quality Improvement in Long Term Care 2Health News:Sixteen Genesis HealthCare Centers Receive Prestigious Award for Continuous Quality Improvement in Long Term Care 3Health News:Longitudinal study investigates cocaine's impact on adolescent development 2Health News:Study finds adverse effects in treatment for primary sclerosing cholangitis 2Health News:Confronting Health Disparities Among Lesbian, Gay, Bisexual and Transgender Youth 2Health News:Confronting Health Disparities Among Lesbian, Gay, Bisexual and Transgender Youth 3Health News:Rapid Fire Marketing Enters Medical Cannabis Business 2Health News:Rapid Fire Marketing Enters Medical Cannabis Business 3
(Date:1/23/2015)... Pa. , Jan. 23, 2015  MedScope ( www.medscope.org ... been nominated for a 2015 Connected World ... Emergency Response System (mPERS), that can be used anywhere, ... technology partner.  In nominating MedScope, ...
(Date:1/23/2015)...  Pete Rose, baseball,s all-time hits leader, is the new spokesperson ... Ducere Pharma has announced. "Pete,s a Hall of ... him on board with Myoflex," said Ducere Pharma Chief Executive ... who is known across all generations. The passion and intensity ...
(Date:1/23/2015)... , Jan. 23, 2015  Lixte Biotechnology Holdings, Inc. (OTCQB: LIXT), ... I trial of Lixte,s lead compound, LB‑100, is being conducted, ... John S. Kovach , M.D., the founder and President ... be completed at a single site. Accrual of patients, however, ...
Breaking Medicine Technology:MedScope Nominated by RacoWireless for Prestigious 2015 Connected World Magazine Connected World Award 2Pete Rose bets on Myoflex to relieve aches and pains 2Lixte Biotechnology Holdings Announces Expansion Of Clinical Sites For Its Phase I Trial Of Its Lead Anti-Cancer Compound, LB-100 2Lixte Biotechnology Holdings Announces Expansion Of Clinical Sites For Its Phase I Trial Of Its Lead Anti-Cancer Compound, LB-100 3
... BOSTON and RIDGEFIELD, Conn., Oct. 30, 2010 Boehringer ... Ib study, SOUND-C1, that showed the combination of two ... BI 201335 and the polymerase inhibitor BI 207127, with ... quantifiable levels in HCV treatment-naive patients. The regimen did ...
... 29 AVANIR Pharmaceuticals, Inc. (Nasdaq: ... and Drug Administration (FDA) has approved NUEDEXTA™ (dextromethorphan ... treatment for pseudobulbar affect.   NUEDEXTA ... (PBA).  PBA occurs secondary to a variety of ...
Cached Medicine Technology:Results of Boehringer Ingelheim Oral Hepatitis C Protease Inhibitor and Polymerase Inhibitor Combination Phase Ib Trial Shows Rapid Viral Response Without Use of Pegylated Interferon 2Results of Boehringer Ingelheim Oral Hepatitis C Protease Inhibitor and Polymerase Inhibitor Combination Phase Ib Trial Shows Rapid Viral Response Without Use of Pegylated Interferon 3Results of Boehringer Ingelheim Oral Hepatitis C Protease Inhibitor and Polymerase Inhibitor Combination Phase Ib Trial Shows Rapid Viral Response Without Use of Pegylated Interferon 4AVANIR Pharmaceuticals Announces FDA Approval of NUEDEXTA™ 2AVANIR Pharmaceuticals Announces FDA Approval of NUEDEXTA™ 3AVANIR Pharmaceuticals Announces FDA Approval of NUEDEXTA™ 4AVANIR Pharmaceuticals Announces FDA Approval of NUEDEXTA™ 5AVANIR Pharmaceuticals Announces FDA Approval of NUEDEXTA™ 6
... Precision Hand Instruments were developed in surgeon's ... while still having an instrument with the ... the fear of the bending or breaking. ... manufactured to conform to the surgeon's hand. ...
... Precision Hand Instruments were developed in surgeon's ... while still having an instrument with the ... the fear of the bending or breaking. ... manufactured to conform to the surgeon's hand. ...
... were developed in surgeon's desire to have ... an instrument with the strength to maneuver ... the bending or breaking. Arthrotek Hand Instruments ... to the surgeon's hand. This new generation ...
... Stryker Universal ACL Instrumentation System has ... a variety of anterior cruciate ligament ... Universal ACL Instrumentation system and endoscopic ... obtain more reproducible anatomical graft placement ...
Medicine Products: