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Monogram Announces First Medicare Payment for Trofile(TM)
Date:9/24/2007

Medicare to Pay for Trofile at Monogram's List Price

SOUTH SAN FRANCISCO, Calif., Sept. 24 /PRNewswire-FirstCall/ -- Monogram Biosciences, Inc. (Nasdaq: MGRM) today announced that the first Medicare payment for its Trofile Assay has been processed, at an amount equal to Monogram's list price, by the National Heritage Insurance Company (NHIC), the contractor that administers Medicare programs in California.

NHIC had previously established coding guidance for Trofile. For patients throughout the U.S., Medicare claims for Trofile are submitted to NHIC, which is the local Medicare part B Contractor in California, where Trofile tests are performed. NHIC's coding guidance for healthcare providers references the need for tropism testing as indicated in the FDA labeling for maraviroc, and acknowledges that Monogram's Trofile Assay was the test for tropism on which the FDA clinical trials of Selzentry (maraviroc) were based.

Monogram's Trofile Assay is the only clinically validated assay for assessing tropism of patients, is the only assay that has been used in phase II and phase III clinical trials of CCR5 antagonists, and has been used in all such clinical trials to date.

"Providing this reimbursement for Trofile is an important acknowledgement by Medicare of the value of Trofile as a tool for guiding the use of Selzentry," said William D. Young, Monogram CEO. "We are making good progress in our discussions with other public and private payers with regard to reimbursement for Trofile and, to date, we have submitted claims to 15 separate payers. We are encouraged by the initial adoption of Trofile by physicians."

About Trofile

Trofile is a patient selection co-receptor tropism assa
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SOURCE Monogram Biosciences, Inc.
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