Navigation Links
Monkey Study Suggests Long-Term Use of ADHD Drugs Safe
Date:7/19/2012

THURSDAY, July 19 (HealthDay News) -- Long-term use of drugs to treat attention-deficit hyperactivity disorder (ADHD) does not affect brain development or increase the risk of drug abuse, according to a study conducted in monkeys.

Monkeys are good for this type of research because they have relatively long periods of childhood and adolescence that feature hormonal and physical changes much like those that occur in humans, explained the researchers from Wake Forest Baptist Medical Center in Winston-Salem, N.C.

The ages of the 16 juvenile monkeys used in this study were equivalent to 6- to 10-year-old humans. Eight of the monkeys received an extended-release form of the ADHD drug Ritalin for more than a year, which is equivalent to about four years in human children. Eight other monkeys in a control group did not receive any drug treatment.

Imaging scans of all the monkeys' brains were conducted before and after the study, to detect any changes in brain chemistry and structure. The researchers also assessed the monkeys' physical growth.

"After one year of drug therapy, we found no long-lasting effects on the neurochemistry of the brain, no changes in the structure of the developing brain," Linda Porrino, chairwoman of Wake Forest's physiology and pharmacology department, said in a university news release. "There was also no increase in the susceptibility for drug abuse later in adolescence."

"We were very careful to give the drugs in the same doses that would be given to children," she added. "That's one of the great advantages of our study is that it's directly translatable to children."

The study was published online in the July issue of the journal Neuropsychopharmacology.

As many as 5 percent to 7 percent of elementary school children in the United States have been diagnosed with ADHD, which is a behavioral disorder that causes inattention, hyperactivity, impulsivity or a combination of these traits.

Many children with ADHD are prescribed drugs, but little is known about their long-term effects.

"Our study showed that long-term therapeutic use of drugs to treat ADHD does not cause long-term negative effects on the developing brain and, importantly, it doesn't put children at risk for substance abuse later in adolescence," Porrino said.

Although monkeys are similar to humans, the results of this research may not be the same in humans.

More information

The U.S. National Institute of Mental Health has more about attention-deficit hyperactivity disorder.

-- Robert Preidt

SOURCE: Wake Forest Baptist Medical Center, news release, July 18, 2012


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Researchers see BPA effects in monkey mammary glands
2. University of Texas Medical Branch to study hospital readmission
3. Fatal Car Crashes Less Likely in Major Cities, CDC Study Finds
4. Study implements community-based approach to treat HIV-infection in rural Uganda
5. Herbal remedy used to treat hepatitis C proves ineffective, Penn study finds
6. Surgery Not Best Option for Early Stage Prostate Cancers: Study
7. Kids Sexual Behavior Influenced by Movie Scenes: Study
8. New study: Elderly Medicare beneficiaries most satisfied with their health insurance
9. Study Gives First Evidence That Adult Human Lungs Can Regrow
10. Study shows colon and rectal tumors constitute a single type of cancer
11. Spouses of severe-sepsis patients at high risk of depression, U-M study shows
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Monkey Study Suggests Long-Term Use of ADHD Drugs Safe
(Date:6/24/2016)... ... June 24, 2016 , ... The Pulmonary Hypertension Association ... it will receive two significant new grants to support its work to advance ... 25th anniversary by recognizing patients, medical professionals and scientists for their work in ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San ... Society and the Road To Recovery® program to drive cancer patients to and from ... adults to ensure the highest quality of life and ongoing independence. Getting to ...
(Date:6/24/2016)... ... June 24, 2016 , ... EB ... Decision Making in Emergency Medicine conference in Ponte Vedra Beach, FL. The awards ... in Emergency Medicine Practice and Pediatric Emergency Medicine Practice. , “With ...
(Date:6/24/2016)... ... June 24, 2016 , ... Strategic Capital Partners, ... economy by obtaining investment capital for emerging technology companies. SCP has delivered ... already resulted in more than a million dollars of capital investment for five ...
(Date:6/24/2016)... ... 2016 , ... Today, MTI-GlobalStem, a provider of optimized transfection ... to transfect cells, announces its launch of the PluriQ™ G9™ Gene Editing System ... is a complete system for culturing and transfecting human pluripotent stem cells for ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... , June 24, 2016 According ... by Type (Standard Pen Needles, Safety Pen Needles), Needle ... GLP-1, Growth Hormone), Mode of Purchase (Retail, Non-Retail) - ... This report studies the market for the forecast period ... reach USD 2.81 Billion by 2021 from USD 1.65 ...
(Date:6/24/2016)... , June 24, 2016  Arkis BioSciences, ... less invasive and more durable cerebrospinal fluid treatments, ... funding.  The Series-A funding is led by Innova ... Fund, and other private investors.  Arkis, new financing ... instrumentation and the market release of its in-licensed ...
(Date:6/23/2016)... 2016 Any dentist who has made an implant ... process. Many of them do not even offer this as ... high laboratory costs involved. And those who ARE able to ... a high cost that the majority of today,s patients would ... Parsa Zadeh , founder of Dental Evolutions Inc. and inventor ...
Breaking Medicine Technology: