Navigation Links
Monkey Gene That Blocks AIDS Viruses Evolved More Than Once

Findings hint epidemic is not unique to present, afflicted humans' primate ancestors

FRIDAY, Feb. 29 (HealthDay News) -- A gene in Asian monkeys that may have evolved as protection against a group of viruses that includes HIV has been identified by Harvard Medical School researchers, who add that their finding suggests the current AIDS epidemic is not a new kind of scourge.

The TRIM5-CypA gene found in Asian macaques is a hybrid of two existing proteins, TRIM5 and CypA. This combination creates a single protein that blocks infections by lentiviruses.

This is the second time a TRIM5-CypA hybrid gene has been identified in monkeys. The other one -- TRIMCyp -- was found in South American owl monkeys in 2004. But it's not likely that these two gene combinations arose from a single common ancestor, the Harvard researchers said.

TRIM5-CypA wasn't found in monkey closely related to the Asian macaques and TRIMCyp wasn't found in any other South American primate species. This suggests that the two combination genes evolved separately, once in the macaques and once in the owl monkeys.

This development of similar genetic adaptations in different species is called convergent evolution. A prime example is the development of flight in bats and in birds.

The fact that adaptations involving TRIM5 and CypA occurred at least twice in primates suggests that this combination provided a strong evolutionary advantage, the Harvard researchers said.

It may be possible that the combination genes developed to prevent infection by prehistoric viruses related to modern HIV, they suggested. If this is true, it could mean that an AIDS-like epidemic is not unique to the current time, and such outbreaks may have afflicted the primate ancestors of humans.

The study is published in the Feb. 29 issue of PLoS Pathogens.

More information

The U.S. Centers for Disease Control and Prevention has more about HIV/AIDS.

-- Robert Preidt

SOURCE: Public Library of Science, news release, Feb. 28, 2008

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Monkey Moms Use Baby Talk, Too
2. Progression of SIV infection in monkeys raises
3. Parasites a key to the decline of red colobus monkeys in forest fragments
4. Protein Nasal Spray Revives Sleep-Deprived Monkeys
5. Cholesterol byproduct blocks heart health benefits of estrogen
6. Toy Blocks Might Boost Toddlers Language Skills
7. Drug Combo Blocks Pain Without Impairing Movement
8. Grape powder blocks genes linked to colon cancer
9. Super-Thin Drug-Free Coating Hides Stent as It Unblocks Heart Arteries
10. Iowa State chemists track how drug changes, blocks flu virus
11. New viruses to treat bacterial diseases -- My enemies enemy is my friend
Post Your Comments:
Related Image:
Monkey Gene That Blocks AIDS Viruses Evolved More Than Once
(Date:11/27/2015)... ... , ... According to an article published November 13th on, ... D.C. revolved around the fact that proper dental care, both at-home and in the ... between periodontal disease (more commonly referred to as gum disease) and diabetes. According to ...
(Date:11/27/2015)... (PRWEB) , ... November 27, 2015 , ... ... affecting the health care in America. As people age, more care is needed, ... costs are rising, and medical professionals are being overworked. The forgotten part of ...
(Date:11/27/2015)... ... November 27, 2015 , ... "When I was traveling, ... from Hillside, N.J. "Many people catch diseases simply from sitting on such dirty ... be protected from germs." , He developed the patent-pending QUDRATECS to eliminate the ...
(Date:11/27/2015)... ... 2015 , ... ProSidebar: Fashion is a set of 30 kinetic ... Fasion, video editors can easily add an informative sidebar to any FCPX production. ... presets featuring self-animating drop zones, lines, bars, and text with the ease of FCPX's ...
(Date:11/27/2015)... (PRWEB) , ... November 27, 2015 , ... ... of the well-respected Microsoft Dynamics SL User Group (MSDSLUG). Recognized as Microsoft’s official ... independent group of Microsoft Dynamics SL software users, partners, industry experts and representatives. ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... 26, 2015 Research and Markets ( ) ... Pacemaker Market Outlook to 2019 - Rise in Cardiac Disorders ... report to their offering. Boston ... Boston scientific and others. --> ... Biotronik, Boston scientific and others. ...
(Date:11/26/2015)... DUBLIN , Nov. 26, 2015 ... the addition of the "2016 Future Horizons ... Monitoring (TDM) Market: Supplier Shares, Country Segment Forecasts, ... offering. --> ... comprehensive analysis of the Japanese therapeutic drug monitoring ...
(Date:11/26/2015)... 26, 2015 ... of the  "2016 Future Horizons and ... Surface Testing Market: Supplier Shares, Competitive ... offering.  --> ) ... "2016 Future Horizons and Growth Strategies ...
Breaking Medicine Technology: