Navigation Links
Monkey Gene That Blocks AIDS Viruses Evolved More Than Once
Date:2/29/2008

Findings hint epidemic is not unique to present, afflicted humans' primate ancestors

FRIDAY, Feb. 29 (HealthDay News) -- A gene in Asian monkeys that may have evolved as protection against a group of viruses that includes HIV has been identified by Harvard Medical School researchers, who add that their finding suggests the current AIDS epidemic is not a new kind of scourge.

The TRIM5-CypA gene found in Asian macaques is a hybrid of two existing proteins, TRIM5 and CypA. This combination creates a single protein that blocks infections by lentiviruses.

This is the second time a TRIM5-CypA hybrid gene has been identified in monkeys. The other one -- TRIMCyp -- was found in South American owl monkeys in 2004. But it's not likely that these two gene combinations arose from a single common ancestor, the Harvard researchers said.

TRIM5-CypA wasn't found in monkey closely related to the Asian macaques and TRIMCyp wasn't found in any other South American primate species. This suggests that the two combination genes evolved separately, once in the macaques and once in the owl monkeys.

This development of similar genetic adaptations in different species is called convergent evolution. A prime example is the development of flight in bats and in birds.

The fact that adaptations involving TRIM5 and CypA occurred at least twice in primates suggests that this combination provided a strong evolutionary advantage, the Harvard researchers said.

It may be possible that the combination genes developed to prevent infection by prehistoric viruses related to modern HIV, they suggested. If this is true, it could mean that an AIDS-like epidemic is not unique to the current time, and such outbreaks may have afflicted the primate ancestors of humans.

The study is published in the Feb. 29 issue of PLoS Pathogens.

More information

The U.S. Centers for Disease Control and Prevention has more about HIV/AIDS.



-- Robert Preidt



SOURCE: Public Library of Science, news release, Feb. 28, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Monkey Moms Use Baby Talk, Too
2. Progression of SIV infection in monkeys raises
3. Parasites a key to the decline of red colobus monkeys in forest fragments
4. Protein Nasal Spray Revives Sleep-Deprived Monkeys
5. Cholesterol byproduct blocks heart health benefits of estrogen
6. Toy Blocks Might Boost Toddlers Language Skills
7. Drug Combo Blocks Pain Without Impairing Movement
8. Grape powder blocks genes linked to colon cancer
9. Super-Thin Drug-Free Coating Hides Stent as It Unblocks Heart Arteries
10. Iowa State chemists track how drug changes, blocks flu virus
11. New viruses to treat bacterial diseases -- My enemies enemy is my friend
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Monkey Gene That Blocks AIDS Viruses Evolved More Than Once
(Date:12/7/2016)... ... ... A. Kevin Spann Insurance, a New York-based firm offering insurance and financial ... charity drive to raise funds that will benefit the Marine Corps League. , The ... FMF Corpsmen. Working closely with the MCL, the A. Kevin Spann team plans to ...
(Date:12/7/2016)... ... December 07, 2016 , ... Delete® - Tattoo Removal and Laser Salon Offers ... Season. Save Up To 33% Off Botox® and Juvederm® Products Now Through December 31, ... with Delightful Deals on Botox® and Juvederm® just in time for the ...
(Date:12/7/2016)... ... December 07, 2016 , ... Gensuite is honored to ... the Best New Product Launch category. Gensuite’s entry on their EZ Scan feature ... Global Events & Training Group is a professional event and training provider based ...
(Date:12/7/2016)... ... December 07, 2016 , ... “Walking With God: Inspirational Lessons from My ... the reader to be aware of God's direction in their lives. “Walking With God: ... retired teacher and active church leader. , Sanford says, “I enjoy sharing ...
(Date:12/7/2016)... ... December 07, 2016 , ... NuevaCare, a leading home care agency based ... announce new city-specific pages as part of its ambitious website relaunch. As Bay Area ... first, for local agencies serving their city. The new site has several key city-specific ...
Breaking Medicine News(10 mins):
(Date:12/6/2016)... 2016  Licenders is bringing their 100% all-natural lice removal service ... Slope at 203 13 th Street was specifically chosen to ... "Our goal is to ease parents, stress and bring ... get children right back to class without skipping a beat. The ... safe for the whole family," Licenders President Adie Horowitz ...
(Date:12/6/2016)... 2016 Diabetes & Obesity Drug Development Pipeline ... disease cluster is currently dominated by therapeutics indicated for ... mellitus (T2DM), and the majority of the pipeline, in ... attributable to these indications. While products indicated for obesity ... are a large number of these products in the ...
(Date:12/6/2016)... -- Human Vaccines Market: Scope and Methodology ... wise analysis of the human vaccines market. Stakeholders ... products, raw material suppliers, vaccine processing companies, and ... The report provides qualitative and quantitative analysis of ... market dynamics, trends, product overview, and country-level market ...
Breaking Medicine Technology: