Navigation Links
Monitoring immune responses in disease
Date:9/3/2008

Amsterdam, September 3, 2008 A recent study (doi:10.1016/j.clim.2008.06.009) published in Clinical Immunology, the official journal of the Clinical Immunology Society (CIS), describes a new method enabling the detection of multiple parameters of single human cells. The report demonstrates the characterization of specific blood cells from an individual with type 1 diabetes, providing information about the role these cells might play in the development of the disease and during therapy.

Classification of blood cells, including B and T cells, is important for distinguishing immune responses to pathogens, allergens, or self-antigens in autoimmune diseases. Although various techniques are available to identify cell surface determinants, cytokines and antibodies secreted by blood cells, so far it has not been possible to study multiple secreted proteins while also assigning surface displayed markers to individual living cells.

A collaborative group of investigators from Harvard Medical School and Massachusetts Institute of Technology in the USA, describe how a combination of existing and enhanced immunological methods can identify and characterize rare B cells from blood of a recent onset type 1 diabetic subject.

"Although this is a small pilot study, it is a useful proof of principle for single cell interrogation methodology, which is potentially of general utility", according to immunologist Gerald Nepom from the University of Washington, School of Medicine in Seattle, USA in his commentary published in the same issue of Clinical Immunology (http://www.elsevier.com/locate/yclim).

"This article describes a very exciting new immunodiagnostic tool, potentially enabling the discovery of novel biomarkers for the pathogenesis of immunologic disorders and in monitoring therapy", said Andy Saxon", the Editor-in-Chief of the CIS journal.


'/>"/>

Contact: Floris de Hon
f.hon@elsevier.com
31-203-842-498
Elsevier
Source:Eurekalert

Page: 1

Related medicine news :

1. System Planning Corporation Launches New Asset Tracking and Monitoring System to Meet Pharmaceutical Industry Needs
2. IntegriChain Enlists Ed Casey and Associates to Drive Counterfeit and Diversion Monitoring Service
3. Transcutaneous cervical esophageal ultrasound can not substitute for 24-h pH monitoring or manometry
4. Axeda Selected for Remote Monitoring and Service of Automation Technologies
5. Singulex Announces Presentation on Monitoring of Cardiac Biomarker to Assess Transient Myocardial Ischemia at the American Heart Association Scientific Sessions
6. Novant Health(R) Selects Cardiocom(R) to Provide Telemonitoring for Presbyterian Hospital Heart Failure Program
7. Cavidi Signs Agreement With the Clinton Foundation HIV/AIDS Initiative to Lower Costs of HIV Monitoring
8. Statement of Steve Pasierb, President and CEO, Partnership for a Drug-Free America on the Release of the 2007 Monitoring the Future Study
9. Gary Tschautscher of Nonin Medical, Inc. Receives CEO of 2007 for North American Patient Monitoring From Frost & Sullivan
10. EaglePicher Technologies Introduces First Implantable Medical Cell Designed Specifically for Monitoring Applications
11. Bergen County (NJ) Early Adopter of Health Monitoring Systems Mergence(TM) Healthcare Data Integration Engine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/23/2017)... ... 2017 , ... The non-profit Seafood Nutrition Partnership (SNP) ... the Science Symposium in partnership with the Global Organization for EPA and DHA ... a forum for global leaders in human nutrition to outline the latest consensus ...
(Date:8/22/2017)... ... August 22, 2017 , ... Western North ... at a popular international aesthetics conference for medical professionals about the positive impact ... health and his growing practice. , Dr. George K. Ibrahim shared ...
(Date:8/22/2017)... ... 22, 2017 , ... Nurses at Apple Rehab Watch Hill , a ... training and certification in Closed Pulse Irrigation™ (CPI) for wound care. This ... the Centers for Medicare and Medicaid Services, to have a CPI machine that will ...
(Date:8/22/2017)... , ... August 22, 2017 , ... ... story of child abuse and neglect, and the struggles faced while hoping for ... the creation of published author, Judy Von Bernewitz, who spent 13 years working ...
(Date:8/22/2017)... ... August 22, 2017 , ... TopConsumerReviews.com recently gave a best-in-class 5-star rating ... , As the stress of modern life continually makes more demands on time and ... artificial stimulants can trap people in vicious high/low cycles and can also cause long ...
Breaking Medicine News(10 mins):
(Date:8/15/2017)... , Aug. 15, 2017  AOTI Inc. announced today that its ... Inc., has recently opened a New York City Office in ... of its unique Topical Wound Oxygen (TWO 2 ) homecare therapy. ... Accreditation Commission for Health Care (ACHC) under the company,s DMEPOS accreditation ... ...
(Date:8/11/2017)... -- DarioHealth Corp. (NASDAQ: DRIO), a leading global digital ... today announced that it will release its second quarter ... conference call at 9:00am ET. The Company will discuss ... its strategy and outlook for the remainder of 2017. The ... , Chief Executive Officer, and Zvi Ben-David , ...
(Date:8/8/2017)... TEL AVIV, Israel, Aug. 8, 2017  BioLineRx Ltd. ... and immunology, today reports its financial results for the ... and achievements during the second quarter 2017 and to ... on multiple clinical development programs for the Company,s lead ... Phase 3 pivotal study with BL-8040 as novel stem ...
Breaking Medicine Technology: