Navigation Links
Monitoring immune responses in disease
Date:9/3/2008

Amsterdam, September 3, 2008 A recent study (doi:10.1016/j.clim.2008.06.009) published in Clinical Immunology, the official journal of the Clinical Immunology Society (CIS), describes a new method enabling the detection of multiple parameters of single human cells. The report demonstrates the characterization of specific blood cells from an individual with type 1 diabetes, providing information about the role these cells might play in the development of the disease and during therapy.

Classification of blood cells, including B and T cells, is important for distinguishing immune responses to pathogens, allergens, or self-antigens in autoimmune diseases. Although various techniques are available to identify cell surface determinants, cytokines and antibodies secreted by blood cells, so far it has not been possible to study multiple secreted proteins while also assigning surface displayed markers to individual living cells.

A collaborative group of investigators from Harvard Medical School and Massachusetts Institute of Technology in the USA, describe how a combination of existing and enhanced immunological methods can identify and characterize rare B cells from blood of a recent onset type 1 diabetic subject.

"Although this is a small pilot study, it is a useful proof of principle for single cell interrogation methodology, which is potentially of general utility", according to immunologist Gerald Nepom from the University of Washington, School of Medicine in Seattle, USA in his commentary published in the same issue of Clinical Immunology (http://www.elsevier.com/locate/yclim).

"This article describes a very exciting new immunodiagnostic tool, potentially enabling the discovery of novel biomarkers for the pathogenesis of immunologic disorders and in monitoring therapy", said Andy Saxon", the Editor-in-Chief of the CIS journal.


'/>"/>

Contact: Floris de Hon
f.hon@elsevier.com
31-203-842-498
Elsevier
Source:Eurekalert

Page: 1

Related medicine news :

1. System Planning Corporation Launches New Asset Tracking and Monitoring System to Meet Pharmaceutical Industry Needs
2. IntegriChain Enlists Ed Casey and Associates to Drive Counterfeit and Diversion Monitoring Service
3. Transcutaneous cervical esophageal ultrasound can not substitute for 24-h pH monitoring or manometry
4. Axeda Selected for Remote Monitoring and Service of Automation Technologies
5. Singulex Announces Presentation on Monitoring of Cardiac Biomarker to Assess Transient Myocardial Ischemia at the American Heart Association Scientific Sessions
6. Novant Health(R) Selects Cardiocom(R) to Provide Telemonitoring for Presbyterian Hospital Heart Failure Program
7. Cavidi Signs Agreement With the Clinton Foundation HIV/AIDS Initiative to Lower Costs of HIV Monitoring
8. Statement of Steve Pasierb, President and CEO, Partnership for a Drug-Free America on the Release of the 2007 Monitoring the Future Study
9. Gary Tschautscher of Nonin Medical, Inc. Receives CEO of 2007 for North American Patient Monitoring From Frost & Sullivan
10. EaglePicher Technologies Introduces First Implantable Medical Cell Designed Specifically for Monitoring Applications
11. Bergen County (NJ) Early Adopter of Health Monitoring Systems Mergence(TM) Healthcare Data Integration Engine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... women who received the Human Papillomavirus Vaccination (HPV) ... of abnormal Pap test results than those who ... journal Sexually Transmitted Diseases . , ... and School of Medicine conducted a cross-sectional study ... routine cervical cytology testing. HPV status and demographic ...
(Date:7/24/2014)... According to market research report "3D Mapping Market: ... Analysis - 2018", the 3D mapping and 3D ... by 2018 at a CAGR of 47.9% by ... and 30 figures spread through 222 pages and ... Business Models, Technology Roadmap, Forecasts and Analysis - ...
(Date:7/24/2014)... York (PRWEB) July 24, 2014 ... ( http://www.drugbot.com/testosterone/lawsuit/ ) against the manufacturer of Delatestryl, ... risks associated with the low testosterone injection, Bernstein ... was filed in the Ontario Superior Court of ... use of low testosterone therapy is associated with ...
(Date:7/24/2014)... 24, 2014 (HealthDay News) -- Giving low-income families vouchers ... increase their consumption of these healthy foods, according to ... fewer fruits and vegetables. In addition to not having ... issue. Farmers, market vouchers could help address both of ... healthy food options, farmers, market incentives may be able ...
(Date:7/24/2014)... new formulation of a powerful narcotic painkiller that discourages ... been approved by the U.S. Food and Drug Administration. ... the pill is a combination of the narcotic oxycodone ... of oxycodone. The naloxone is only activated when the ... the FDA. While Targiniq has only been approved ...
Breaking Medicine News(10 mins):Health News:3D Mapping & 3D Modeling Market Projected to $7.7 Billion by 2018 - Report by MarketsandMarkets 2Health News:3D Mapping & 3D Modeling Market Projected to $7.7 Billion by 2018 - Report by MarketsandMarkets 3Health News:3D Mapping & 3D Modeling Market Projected to $7.7 Billion by 2018 - Report by MarketsandMarkets 4Health News:Testosterone Lawsuit News: Canadian Plaintiffs File Class Action Lawsuit Against Manufacturer of Delatestryl Testosterone Injection, Bernstein Liebhard LLP Reports 2Health News:Testosterone Lawsuit News: Canadian Plaintiffs File Class Action Lawsuit Against Manufacturer of Delatestryl Testosterone Injection, Bernstein Liebhard LLP Reports 3Health News:Farmers' Market Vouchers May Help Poorer Families Eat Healthier 2Health News:FDA Approves Hard-to-Abuse Narcotic Painkiller 2
... GenPrime, Inc. a leading,provider of rapid microbial analysis ... Contamination Test for Platelets(TM). The,test is a rapid ... and,anaerobic bacteria commonly found in contaminated platelets. The ... pre-market notification with the Food,and Drug Administration (FDA). ...
... ago, deconstructing and analyzing DNA codes took scientists several years ... floor of a building. Now, a genetic sequencer the ... a couple of days. , Thanks to a ... of Houstons Institute for Molecular Design (IMD), researchers will be ...
... example of the Bush Administration promoting, politics over a sound health ... oversight of the federal family planning program and the health of ... ... National Abortion,Federation (NAF) denounces the appointment of Dr. Susan Orr as ...
... Next Big Challenge, WASHINGTON, Oct. 17 Is ... drugs,and devices to physicians and the public?, That,s ... and debate at a,landmark Colloquium, Communicating Risk/Safety Information: How ... Drug Law Institute (FDLI),Dec. 6, 2007, in Washington, D.C., ...
... Oct. 17 40|86 Strategic Income,Fund (NYSE: CFD ... 9, 2007 to holders of record at the close ... Fund is a closed-end investment management,company. The Fund,s primary ... in the Fund,s prospectus, the Fund intends to,distribute substantially ...
... Care, Inc. (NYSE:,HCR) announced that at its special ... merger agreement providing for the,merger of Manor Care, ... 99 percent of the shares present and voting ... number of shares voting to approve,the merger agreement ...
Cached Medicine News:Health News:GenPrime Initiates External Clinical Trials of its Bacterial Contamination Test for Rapid Detection of Bacteria in Platelets 2Health News:Half-million-dollar DNA sequencer to boost genetic science research at UH 2Health News:National Abortion Federation Denounces the Appointment of Dr. Orr to Oversee Federal Family Planning Funds 2Health News:Food and Drug Law Institute Sponsors Colloquium on Communicating Risk/Safety Drug Information 2
(Date:7/24/2014)... -- Delivery of the Report will take 2-3 ... Photo - http://photos.prnewswire.com/prnh/20140723/129707 ... on Global and Chinese Hemodialysis Machine industry. The ... Machine including its classification, application and manufacturing technology. ... manufacturers of Hemodialysis Machine listing their product specification, ...
(Date:7/24/2014)... 24, 2014 Cancer patients in the west of ... cancer treatment closer to home when a new radiotherapy center ... Medical Systems (NYSE: VAR ) has been selected ... in June for four TrueBeam™ medical linear accelerators. ... and efficient radiotherapy and radiosurgery treatments, will replace older treatment ...
(Date:7/24/2014)...  Blueprint Medicines (Blueprint), a leader in discovering highly ... announced the appointment of Jeffrey Albers as ... Algeta ASA, where he served on the executive management ... Bayer. Mr. Albers succeeds Alexis Borisy , co-founder ... Rock Ventures, who will remain an active member of ...
Breaking Medicine Technology:Hemodialysis Machine Industry for Global and Chinese Markets Forecast to 2019 2Hemodialysis Machine Industry for Global and Chinese Markets Forecast to 2019 3Hemodialysis Machine Industry for Global and Chinese Markets Forecast to 2019 4Hemodialysis Machine Industry for Global and Chinese Markets Forecast to 2019 5Varian Medical Systems Selected to Equip First Satellite Radiotherapy Center in Scotland 2Varian Medical Systems Selected to Equip First Satellite Radiotherapy Center in Scotland 3Blueprint Medicines Appoints Jeffrey Albers as Chief Executive Officer 2
... , Consumers Oppose Prescription Mandate; Prefer Alternative Method to ... Jan. 30 Mississippians are expressing outrage at lawmakers, ... (PSE) to a prescription (Rx) drug. , "The Consumer ... Mississippians to contact their legislators which within the first day ...
... Jan. 29 The IKF,s (International Kids Fund) ... Children called the " Haiti ,s Children Fund."  It will ... Memorial Hospital for life-saving medical care.  Donations may be made ... program of the Jackson Memorial Foundation, whose mission is to ...
Cached Medicine Technology:Mississippians React to Rushed Pseudoephedrine Debate Raging in the State Legislature 2Mississippians React to Rushed Pseudoephedrine Debate Raging in the State Legislature 3IKF's Wonderfund(TM) Needs Support for Haiti's Children 2
The XT-1800i is a compact, high performance, automated hematology analyzer that provides accurate and precise CBC result including a fully automated WBC 5-part differential, and comprehensive test re...
The XT-2000i is a compact, high performance, automated hematology analyzer that provides accurate and precise CBC result including a fully automated WBC 5-part differential, and comprehensive test re...
The XE-2100L automated hematology analyzer features new hematology parameters as NRBC, IRF, and HPC that offer valuable and accurate clinical information....
The XE-2100 automated hematology analyzer features new hematology parameters as NRBC, IRF, and HPC that offer valuable and accurate clinical information....
Medicine Products: