Navigation Links
Monitoring and control can limit side effects of promising cancer drugs
Date:5/11/2010

A new class of cancer drugs can be used effectively while minimizing hypertensive side effects if patients' blood pressure is closely monitored and controlled, a clinical panel has determined.

The panel brought oncologists, cardiologists and hypertension experts together to draft new recommendations for physicians prescribing angiogenesis inhibitors for the treatment of cancer. First approved in the mid-2000's, these drugs disrupt tumor growth by preventing the formation of new blood vessels, but also increase blood pressure in most patients.

Treating a patient's hypertension before starting the inhibitors and closely monitoring their blood pressure in the days after treatment begins can help physicians control this side effect, the panel concluded this month in the Journal of the National Cancer Institute. Those precautions may allow patients at higher risk for cardiovascular disease to benefit from these novel cancer treatments, authors said.

"This paper should impact practice today," said Michael Maitland, MD, PhD, assistant professor of medicine at the University of Chicago Medical Center and lead author on the commentary. "It should make things safer on average for patients, and will give physicians important guidance."

Several different angiogenesis inhibitors have been studied in clinical trials, and all cause an elevation of blood pressure in most patients. These drugs are also given with increased frequency to patients above 60 years old, a population with a high chance of pre-existing hypertension.

"Often the case is those patients aren't seeking medical attention for hypertension until they find that they have a tumor and need treatment for cancer," Maitland said. "If a patient is hypertensive, a physician should not dismiss that as irrelevant just because they have advanced cancer. We already know that ignoring co-morbidities in a cancer patient can generate as much risk for their long term surviva
'/>"/>

Contact: Robert Mitchum
robert.mitchum@uchospitals.edu
773-702-6241
University of Chicago Medical Center
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Cost Savings from Mobile Health Monitoring to Reach $1.9 billion to $5.8 Billion Globally by 2014 says Juniper Research
2. New Diagnostic Testing Company, Blue Ocean Biomedical, Specializes In Automated, Load & Go Cell Analysis Systems For Immune Monitoring
3. Envisat monitoring changes in oil spill
4. New VKernel AppVIEW 1.0 for Monitoring and Identification of Capacity Bottlenecks in Critical Application VMs
5. CWRU study examines effectiveness of telemonitoring vital signs
6. Revenues from Mobile Health Monitoring to Reach $1.9 Billion Globally by 2014 Says Juniper Research
7. Six Degrees Launches ePulse - an Online Buzz Monitoring Tool
8. IESO, one of the Independent System Operators in North America, Selects MetricStream GRC for Monitoring Compliance to Electric Reliability Standards
9. Improved patient care with telemonitoring
10. The Results Are In: Users of BodyMedia's Wearable Body-Monitoring Technology Lose 3 Times More Weight
11. ANT+ and iTMP Announce the Digifit™ Ecosystem - The First iPhone™ Apps to Integrate Running, Cycling and Heart Rate Monitoring
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... Jiwa Law Corporation, a personal injury law firm in Vancouver, ... free consultation for personal injury claims of their clients. This ... first time to meet the Vancouver ICBC lawyers will not ... what their rights are. The experts at Jiwa Law Corporation ... them what the law firm can do regarding their claim. ...
(Date:9/30/2014)... 2014 Coast Dental and Orthodontics ... its newest practice, located at 1010 Shaw Avenue in ... general dentistry services , and specialty dental care including ... providing affordable and convenient dental care, our Clovis dentists ... . Call Coast Dental at 559-777-6113 to schedule an ...
(Date:9/30/2014)... 2014 In its latest blog post, ... that having family close by during a stay in rehab ... process is successful, is focusing on 5 reasons why relapse ... , “Achieving sobriety is not a one-time event, like reaching ... CEO Per Wickstrom . “It’s an ongoing process and ...
(Date:9/30/2014)... 2014 More than 23 per cent of Canadians report ... stress increases the risk of poor mental and physical health, ... but for others especially those most likely to sweat ... , Thankfully, new research from Concordia University has found a ... huge help for healthcare professionals working to stop stress before ...
(Date:9/30/2014)... 2014Levothyroxine (L-T4), long the standard of care for ... some individuals do not regain optimal health on ... help to explain these differences. An expert task ... hormone replacement reviewed the latest studies on L-T4 ... a change to the current standard of care ...
Breaking Medicine News(10 mins):Health News:Jiwa Law Corporation Now Offers Personal Injury Consultation Without Any Charge 2Health News:Coast Dental Clovis Celebrates Grand Opening 2Health News:Coast Dental Clovis Celebrates Grand Opening 3Health News:New Best Drug Rehabilitation Blog Post Focuses on 5 Reasons Why Relapse Shouldn’t Stand in the Way of Recovery 2Health News:New Best Drug Rehabilitation Blog Post Focuses on 5 Reasons Why Relapse Shouldn’t Stand in the Way of Recovery 3Health News:How to predict who will suffer the most from stress 2Health News:New hypothyroidism treatment guidelines from American Thyroid Association 2
... was brought to the public’s notice that fluoride in water ... protect// the teeth from cavities. But now Dr. Chester Douglass ... a great risk of boys developing for a rare bone ... Dental Medicine. ,He is paid to work as ...
... tryst with Bird-flu leaves telltale cues about best practices ... more about bird-flu and the lethal H5N1 strain, than ... surprising, since Vietnam tops the list of countries badly ... had claimed 42 human lives. , ,With ...
... The African Union and World Health Organization must do something ... medicinal plants// can be preserved in African countries. ... Brazzaville, Congo, last week. It is widely known that almost ... men for their health needs and researchers are increasingly looking ...
... are being made to run , as part of the ... doctors are doing whatever it takes// to create awareness of ... off a pilot programme for 12 weeks that brought into ... programme turned so successful that most children not only shed ...
... cannot hold our breath for a long time as oxygen is ... have recently discovered// how the Crucian Carp, a close relative of ... ,This discovery is of great interest as it helps us ... hope that this understanding of how some animals cope with a ...
... spectrometry has been used to determine the chemical ... been used to identify viruses// especially in complex ... Hopkins Bloomberg School of Public Health successfully ... a clinical sample within a few hours using ...
Cached Medicine News:
(Date:9/30/2014)... Calif. , Sept. 30, 2014 Headquartered ... (OTC: GWPC) is a diversified company comprised of several ... of advanced technology and the proven expertise of its ... health and wellness. WholeHealth Products, line of more than ... healthcare centers, and its more than 8 retail consumer ...
(Date:9/30/2014)...  The Corporate Whistleblower Center is urging ER ... 866-714-6466 if they have well documented proof of ... been sent home, as an intentional way to ... as the Center would like to explain. ... Photo - http://photos.prnewswire.com/prnh/20140929/149017 ...
(Date:9/30/2014)... Netherlands , Sept. 30, 2014  eHealth, ... phone storage and access of this information, has ... Slot , however, that has not translated into ... http://photos.prnewswire.com/prnh/20140929/149122 Photo - http://photos.prnewswire.com/prnh/20140929/149123 ... the past few years developing MWD® Health Manager ...
Breaking Medicine Technology:WholeHealth Products Announces The Discovery Of The "Autism And Fragile X" Microwell And Rapid Diagnostic Test 2Corporate Whistleblower Center Urges ER Doctors or Nurse Managers to Call Them if They Have Proof of a Hospital Needlessly Admitting Medicare Patients Instead of Sending Them Home 2Corporate Whistleblower Center Urges ER Doctors or Nurse Managers to Call Them if They Have Proof of a Hospital Needlessly Admitting Medicare Patients Instead of Sending Them Home 3Corporate Whistleblower Center Urges ER Doctors or Nurse Managers to Call Them if They Have Proof of a Hospital Needlessly Admitting Medicare Patients Instead of Sending Them Home 4MWD Challenges the Big eHealth Players With New Software for Your Smartphone 2
... Inc. (OTC Bulletin Board: LTUS ) ("Lotus" or ... medicine and drugs in the People,s Republic of China ("PRC"), ... of directors and the subsequent appointment of four new directors. ... Li, and Mr. Jun Lu have been appointed to serve ...
... LONDON, Dec. 21, 2010 Many Women suffering from hair loss ... advanced laser therapy as a method along with other procedures ... restoration has been shown to be affective in helping a ... into one overall treatment. A cutting-edge laser device is used in ...
Cached Medicine Technology:Lotus Pharmaceuticals Announces Change of Directors 2Lotus Pharmaceuticals Announces Change of Directors 3Lotus Pharmaceuticals Announces Change of Directors 4Advanced Laser Therapy Solutions for Women's Hair Loss 2
Inquire...
VACUETTE paediatric tubes have decreased sample volumes and are ideal for small childrens' veins and geriatric patients....
BD Vacutainer® Heparin Tubes are spray-coated with either lithium heparin or sodium heparin and are used for plasma determinations in chemistry....
Inquire...
Medicine Products: