Navigation Links
Monitoring Hormone May Improve Kidney Failure Outcomes
Date:8/6/2008

Screening could work best for early-stage patients who don't yet need dialysis, study says

WEDNESDAY, Aug. 6 (HealthDay News) -- Monitoring levels of a hormone called fibroblast growth factor 23 (FGF-23) may help improve treatment of kidney failure patients, say Massachusetts General Hospital researchers.

Their analysis of patient data revealed that those who had elevated levels of FGF-23 when they began hemodialysis were much more likely to die within the first year of treatment, regardless of other risk factors.

Patients with the highest FGF-23 levels had a 600 percent higher death rate than those with the lowest levels. Patients with intermediate FGF-23 levels also had an increased risk of death.

"FGF-23 helps regulate serum phosphate levels; and we know that, among patients with kidney failure, elevated phosphate is associated with more rapid progression to renal failure and earlier death," study leader Dr. Myles Wolf said in an MGH news release. "The results of this study suggest that we need to be concerned about phosphate control even for patients whose serum phosphate levels are normal, and that may involve routine screening for FGF-23."

"Incorporating FGF-23 levels into the management of kidney failure may have its greatest potential for treatment of the millions of patients with early-stage kidney disease who do not yet require dialysis, who usually have normal phosphate levels but quite high FGF-23," Wolf added. "Routinely monitoring FGF-23 may help determine which patients need to begin therapies that control phosphate levels, which may reduce mortality in this very high-risk group."

The study was published in the Aug. 7 issue of the New England Journal of Medicine.

More information

The American Academy of Family Physicians has more about kidney failure.



-- Robert Preidt



SOURCE: Massachusetts General Hospital, news release, Aug. 6, 2008


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. System Planning Corporation Launches New Asset Tracking and Monitoring System to Meet Pharmaceutical Industry Needs
2. IntegriChain Enlists Ed Casey and Associates to Drive Counterfeit and Diversion Monitoring Service
3. Transcutaneous cervical esophageal ultrasound can not substitute for 24-h pH monitoring or manometry
4. Axeda Selected for Remote Monitoring and Service of Automation Technologies
5. Singulex Announces Presentation on Monitoring of Cardiac Biomarker to Assess Transient Myocardial Ischemia at the American Heart Association Scientific Sessions
6. Novant Health(R) Selects Cardiocom(R) to Provide Telemonitoring for Presbyterian Hospital Heart Failure Program
7. Cavidi Signs Agreement With the Clinton Foundation HIV/AIDS Initiative to Lower Costs of HIV Monitoring
8. Statement of Steve Pasierb, President and CEO, Partnership for a Drug-Free America on the Release of the 2007 Monitoring the Future Study
9. Gary Tschautscher of Nonin Medical, Inc. Receives CEO of 2007 for North American Patient Monitoring From Frost & Sullivan
10. EaglePicher Technologies Introduces First Implantable Medical Cell Designed Specifically for Monitoring Applications
11. Bergen County (NJ) Early Adopter of Health Monitoring Systems Mergence(TM) Healthcare Data Integration Engine
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/26/2017)... ... April 26, 2017 , ... ... to announce the ATA 2017 President’s Awards recipients, comprised of organizations and ... healthcare delivery. , The ATA 2017 President’s Awards recognize individuals and ...
(Date:4/26/2017)... ... April 26, 2017 , ... The National ... upon National Registry of Emergency Medical Technicians and welcomes this organization ... Dr. Jan G. West, Ph.D. , CEO & Organizational Psychologist at NBRI. ...
(Date:4/26/2017)... ... April 26, 2017 , ... ... a unique website ( CRISPRCas.pioneer.com ) that demonstrates how this advanced plant breeding ... more and better food, with fewer resources. It highlights the business’ principles, research ...
(Date:4/25/2017)... ... April 25, 2017 , ... Bellus Medical, a leader in ... a new class of photodynamic cosmetics (PDC). , Allumera® is the first PDC ... signs of aging, and minimize the appearance of pores – all with minimal ...
(Date:4/25/2017)... ... April 25, 2017 , ... A stressful work environment can hurt the physical ... productivity and performance in the workplace. The goal of Clearview Resolution Services has always ... of April, Clearview Resolution Services will be shutting down the office early on Fridays. ...
Breaking Medicine News(10 mins):
(Date:4/19/2017)... 19, 2017  Sorrento Therapeutics, Inc. (NASDAQ: ... company developing new treatments for cancer and other ... its previously announced underwritten public offering of 23,625,084 ... offering price of $2.00 per share, before deducting ... payable by Sorrento.  The net proceeds to Sorrento ...
(Date:4/19/2017)... , April 19, 2017  SARES•REGIS Group ... it is developing at Conejo Spectrum Business Park ... to Atara Biotherapeutics, Inc. , a biopharmaceutical ... and life-threatening diseases that have been underserved by ... T-cell therapies for cancer, autoimmune and infectious disease. ...
(Date:4/18/2017)... 18, 2017 Research and Markets has announced ... report to their offering. ... global arthroscopy devices market to grow at a CAGR of 6.35% ... Devices Market 2017-2021, has been prepared based on an in-depth market ... landscape and its growth prospects over the coming years. The report ...
Breaking Medicine Technology: