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Mom's HIV Drugs May Pass to Baby in Womb, Breast-Feeding
Date:7/22/2012

t-feeding. Efavirenz appears to be transmitted in utero and during breast-feeding.

The findings could lead to the development of new ways to protect infants from HIV transmission and shed light on toxicities and resistance to anti-HIV drugs, the study authors noted.

"Our findings, as we verify them, will have important implications. One, being able to measure drug exposures of fetuses in the womb and during breast-feeding can help us understand how to better protect infants from HIV transmission from HIV-positive mothers during pregnancy, birth and after birth," said Gandhi. "Second, the development of resistance to antiretroviral medications in infants is an important issue," she added.

After low levels of exposure, HIV can develop resistance to the class of medications to which efavirenz belongs, she explained.

The study was expected to be presented on Saturday at the 4th International Workshop on HIV Pediatrics in Washington, D.C., ahead of a presentation at the 19th International AIDS Conference. The data and conclusions of research presented at medical meetings should be viewed as preliminary until published in a peer-reviewed journal.

More information

The U.S. Centers for Disease Control and Prevention has more about mother-to-child HIV Transmission and Prevention.

-- Mary Elizabeth Dallas

SOURCE: University of California, San Francisco, news release, July 21, 2012


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