Navigation Links
Molecular meet and greet
Date:8/18/2011

spected that these pre-formed clusters aid in signaling, so to test that theory, they disrupted the cytoskeleton. Sure enough, when the corridors disappeared, the cell no longer responded effectively to oxLDL.

Jaqaman compares the receptors in linear paths to people in the hallway of an office building. "People in the hallway are much more likely to bump into and chat with colleagues than people who stay in their offices all day, like receptors trapped in actin cages, or people wandering around the city, like receptors wandering freely around the cell surface," she says.

Jaqaman and Danuser stress that the mechanical nature of these structuresand how they relate to the cell's chemical and mechanical environmentmay be key to understanding how healthy and unhealthy cells function, replicate and grow. For example, it is well known, they said, that tumors are mechanically stiffer than normal tissues. In one provocative scenario, Danuser speculates that the broad variation in the mechanical properties between cancer tissues in different patients may be a key reason for the variable success of cancer chemotherapies that target cell-surface receptors.

"While most current research focuses on the study of oncogenes and tumor suppressors, it might be just the intrinsic change in cancer-tissue mechanics that leads to the change of signaling," Danuser said. "I think we absolutely have to look into that."


'/>"/>

Contact: David Cameron
david_cameron@hms.harvard.edu
617-432-0441
Harvard Medical School
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Hebrew U. scientists identify molecular basis for DNA breakage
2. Blocking molecular target could make more cancers treatable with PARP inhibitors
3. Scientists discover new molecular pathway involved in wound-healing and temperature sensation
4. Molecular glue sticks it to cancer
5. Molecular movements could lead to new way to treat cancer
6. Scientists Find Molecular Similarities in Brains of Those With Autism
7. Autism changes molecular structure of the brain, UCLA study finds
8. Finding molecular targets of an HIV drug used in cancer therapy
9. Researchers publish molecular disease model for melanoma
10. Stanford researchers discover molecular determinant of cell identity
11. Using a molecular switch to turn on cancer vaccines
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... Deer Path of Huntley -- a ... Happy Hour from 3 p.m. to 4 p.m. on Feb. 13. ... Huntley, Illinois, serves adults with physical disabilities between the ages of ... Day treats, games and sweetheart-themed karaoke. , For more information about ...
(Date:1/22/2015)... January 23, 2015 LunaDress, with its top ... fashion industry. Now, the business is showing its latest designs ... dresses. , According to the company’s CEO, all the fresh ... offered with big discounts, up to 80% off. All the ...
(Date:1/22/2015)... Gabe’s Chemo Duck Program is pleased to announce the ... created for kids with cancer. The Chemo Duck App, available on ... with enjoyable games to help children of all ages living with ... to keep kids entertained, educated and at ease while waiting for ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 The Incredible Bulk ... Ben Pakulski to increase lean muscle by up to 30lbs ... caught the attention of HealthyandFitZone.com’s Stan Stevenson, prompting an investigative ... it is a step-by-step, scientific diet formula that allows the ...
(Date:1/22/2015)... AngelWeddingDress, the premier women’s dress supplier, has ... View website of AngelWeddingDress.com to find more ... dresses online for a bridal party. AngelWeddingDress offers a ... them. Its maternity wedding dresses are specially designed for ...
Breaking Medicine News(10 mins):Health News:Deer Path of Huntley Affordable Assisted Living to Host Valentine's Day Happy Hour 2Health News:LunaDress Shows The Latest Styles Of Wedding Dresses In 2015 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 2Health News:Chemo Duck Launches First App Ever Created for Kids with Cancer 3Health News:The Incredible Bulk: Review Examining Ben Pakulski’s Brand New Bulking Muscle Building Diet Program Released 2Health News:AngelWeddingDress Has Recently Released Its Collection Of 2015 Maternity Wedding Dresses 2
... distinct regions of the human brain are activated when ... only risk. The investigators found the reason behind why ... become an addition or lead to compulsive gambling. The ... ,The research was supported by the National Institute ...
... of 26 other large studies has found that indicators of ... played a key role in the overall health of the ... learn decrease with age and lead to Alzheimer's disease or ... intellectual pursuits have been shown to delay the onset of ...
... a VAT of 17.5% on them. This is expected to ... budget.,Gordon Brown is due to present the budget later this ... which said that it was confident of the action. The ... followed a successful 10-month campaign. ,Superdrug managing director ...
... product of rice processing, called rice bran, significantly lowers ... humans.// ,Journal of Agricultural and Food Chemistry, ... scientific society holds the nuances of the study. ... Brewing researchers’ showed that if rice ran is added ...
... that women in India are gradually becoming more susceptible ... percent of India’s infected population//. ,"Women are ... lack of education and trafficking of women are making ... women's human rights and human security unit, United Nations ...
... that women who skip their menstrual cycle through contraceptive ... cancers// related to the female reproductive system such as ... the common perception is that regular menses means 'a ... diseases including breast, ovarian and endometrial cancers, says Professor ...
Cached Medicine News:Health News:Distinct Brain Sections Are Activated While Making Risky Decisions 2Health News:Biologically Women Are More Vulnerable To HIV Infection 2
(Date:1/23/2015)... Jan. 23, 2015  HyGreen, Inc., a leader in hand ... with RCA Medical, a subsidiary of Ascendis Health Limited, ... Each year, hundreds of millions of patients around ... organisms are transmitted from patient to patient via the ...
(Date:1/23/2015)... Cord Blood America, Inc. ( www.cordblood-america.com ) (OTC Bulletin Board: ... Preliminary Proxy Statement, Schedule 14A, with the U.S. Securities & ... for shareholders detailing why a "YES" vote to increase the ... As we reflect upon the 2014 fiscal year ...
(Date:1/23/2015)... Gem Pharmaceuticals announced today that the initial soft tissue ... Phase 2 clinical trial.  This open-label study will assess ... (an investigational medication), in approximately 30 adults as first-line ... Logo - http://photos.prnewswire.com/prnh/20150123/170966LOGO GPX-150 is ...
Breaking Medicine Technology:HyGreen Partners with RCA Medical in Johannesburg, South Africa 2Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 2Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 3Cord Blood America Announces Preliminary Proxy Filing and Details Why a "YES" Vote to Increase Authorized Shares Is Requested 4Gem Pharmaceuticals Announces Enrollment of Initial Patients in its Phase 2 Clinical Trial to Assess the Efficacy and Safety of GPX-150 in Sarcoma Patients 2
... Oct. 3, 2011 Varian Medical Systems (NYSE: ... senior managers to support the company,s ongoing growth and ... Vice President for the company, has been named Chief ... development, production, promotion, and sale of all Varian products ...
...   PLC Medical Systems, Inc. (OTC: PLCSF) today announced ... , October 6, 2011TIME: , 11:00 AM ... "register/ watch event now" button.This will be a live, ... the company questions in real-time both in the presentation ...
Cached Medicine Technology:Varian Medical Systems Announces New Management Positions 2Varian Medical Systems Announces New Management Positions 3Varian Medical Systems Announces New Management Positions 4PLC Medical Systems to Present Webcast Live, at RetailInvestorConferences.com on October 6th 2
Soft Non-Latex, Adjustable Flange Nasopharyngeal Airway. Pediatric sizes available. Non-Latex Mediprene material with soft elastic finish. Adjustable flange for a better fit and increased patient com...
Soft Guedel Oral Airways...
All oral and nasal airways are manufactured with smooth, rounded edges for increased patient comfort and safety., ,Portex® offers a broad selection of airways for a variety of clinical applicati...
... ,When a difficult airway must be ... you can be assured of rapid intubation ... double-Lumen Airway from Nellcor. Unlike traditional endotracheal ... establish a nonsurgical patient airway when placed ...
Medicine Products: