Navigation Links
Molecular Devices to Showcase Advanced Assays for High-throughput Assessment
Date:4/28/2017

Early detection and elimination of new chemical entities with cardiac or hERG liability could substantially improve drug safety and minimize the cost of development. In this webinar, sponsored by Molecular Devices, an overview will be provided for validating ion channel inhibition using cell lines and for cardiac toxicity using induced pluripotent stem cells (iPSCs).

In the first segment, high-throughput screening for in vitro potency evaluation of cardiac ion channel inhibitors on the FLIPR Tetra® System, participants will learn to optimize and validate a robust cell-based hERG fluorescence assay using the FLIPR® Potassium Assay Kit, a thallium-sensitive fluorescence dye to directly measure ion influx. They will also learn to run inhibition assays with voltage-gated sodium channels (NaV1.5) and L-type voltage-gated calcium channels (CaV1.2) using FLIPR® Membrane Potential Dye and FLIPR® Calcium 6 Dye, respectively.

In the second segment, participants will learn how to determine the effects of pharmacological compounds and other chemicals on the beating rate and profiles of cardiomyocytes using the FLIPR Tetra system and ImageXpress® Micro system. They will also be able to identify methods for multiparametric analysis and ranking of compounds for potential cardiotoxic hazards.

Dr. Beiyan Zou, a field applications scientist with Molecular Devices and Dr. Oksana Sirenko, a research scientist with Molecular Devices, will be the speakers for this event.

As an 18-year veteran working in molecular biology and genetics, Zuo first received her doctorate degree in biology from Pennsylvania State University and completed postdoctoral training in the Department of Neuroscience at John Hopkins University School of Medicine. She now works as a Field Applications Scientist at Molecular Devices supporting reagents, FlexStation3 reader, FLIPR Tetra system, and automated electrophysiology platforms.

Sirenko is a Research Scientist at Molecular Devices working on development of new technologies for imaging and high-content analysis. Oksana also has previous experience working on drug discovery and drug development. The focus of her current scientific research is on development methods for high-throughput in vitro toxicity screening, including 3D models. She earned a doctorate in biochemistry.

LabRoots will host the event May 9th, 2017, starting at 7:00 a.m. PDT, 10:00 a.m. EDT, 2:00 p.m. GMT. To learn more about this event, the continuing education credits offered, or to registered for free, click here.

About Molecular Devices, LLC
Molecular Devices is one of the world's leading providers of high-performance bioanalytical measurement systems, software and consumables for life science research, pharmaceutical and biotherapeutic development. Included within a broad product portfolio are platforms for high-throughput screening, genomic and cellular analysis, colony selection and microplate detection. These leading-edge products enable scientists to improve productivity and effectiveness, ultimately accelerating research and the discovery of new therapeutics. Molecular Devices is committed to the continual development of innovative solutions for life science applications. The company is headquartered in Silicon Valley, California with offices around the globe.

For more information, visit: http://www.moleculardevices.com/flipr
About LabRoots
LabRoots is the leading scientific social networking website and producer of educational virtual events and webinars. Contributing to the advancement of science through content sharing capabilities, LabRoots is a powerful advocate in amplifying global networks and communities. Founded in 2008, LabRoots emphasizes digital innovation in scientific collaboration and learning, and is a primary source for current scientific news, webinars, virtual conferences, and more. LabRoots has grown into the world’s largest series of virtual events within the Life Sciences and Clinical Diagnostics community.

Read the full story at http://www.prweb.com/releases/2017/04/prweb14283654.htm.


'/>"/>
Source: PRWeb
Copyright©2017 Vocus, Inc.
All rights reserved


Related medicine news :

1. A*STAR scientist wins European Molecular Biology Organization Young Investigator award
2. Molecular Biomarkers for Cancer Detection and Management
3. Bioinformatics Market (Molecular Medicine, Agriculture, Research & Forensic) worth $7.5 Billion by 2017 - New Report by MarketsandMarkets
4. Cincinnati Childrens researchers develop first molecular test to diagnose eosinophilic esophagitis
5. BCC Research Publishes A New Report On Global Markets For Molecular Imaging Devices
6. ATCC Examined the Importance of High-quality Controls in Assay Design and Development During the Association for Molecular Pathology (AMP) 2013 Annual Meeting
7. Treatment plans for brain metastases more accurately determined with aid of molecular imaging trace
8. Maryville, Tennessee based Molecular Pathology Laboratory Network, Inc. (MPLN) Acquires the First FDA Approved High-Throughput DNA Sequencing Analyzer
9. Mayo Clinic: Drug induces morphologic, molecular and clinical remissions in myelofibrosis
10. Supercomputers help ORNL researchers identify key molecular switch that controls cell behavior
11. Polymer coatings based on molecular structures
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... 2017 , ... Many families have long-term insurance that covers care for a ... waiver for care if the client has a cognitive impairment diagnosis. , “What ... is often waived, so the benefits from their insurance start immediately,” said Mechell Vieira, ...
(Date:10/13/2017)... ... October 13, 2017 , ... ... giving viewers the lowdown on sciatica in a new episode of "Success Files," ... on current events and innovation and investigates each subject in-depth with passion and ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... treating sleep apnea using cutting-edge Oventus O2Vent technology. As many as ... disorder characterized by frequent cessation in breathing. Oral appliances can offer significant relief ...
(Date:10/12/2017)... ... October 12, 2017 , ... Asante, a ... health care, have expanded their existing home health joint venture through an agreement, ... been operating a joint venture home health company with Asante, delivering clinically integrated ...
(Date:10/12/2017)... , ... October 12, 2017 , ... On Saturday, October ... treadmill relay – Miles by Moonlight to raise money for the American Heart Association ... more. , Teams will work together to keep their treadmills moving for 5 ...
Breaking Medicine News(10 mins):
(Date:9/25/2017)... 2017   Montrium , an industry leader ... the IQPC Trial Master Files & Inspection Readiness ... EastHORN Clinical Services has selected eTMF Connect ... management. EastHORN, a leading European contract research organization ... transparency to enable greater collaboration with sponsors, improve ...
(Date:9/22/2017)... Sept. 22, 2017 AVACEN Medical (AVACEN) announced ... now successfully helping those with the widespread pain associated ... diagnosed Amanda in Essex, England ... my hair, experiencing no sleep at all, tremendous pain, ... I cannot recommend [the AVACEN 100] enough, how this ...
(Date:9/18/2017)... R.I. , Sept. 18, 2017 /PRNewswire/ ... the fields of bioinformatics and immune engineering, ... a protective avian influenza A (H7N9) vaccine. ... distantly related to seasonal influenza and presents ... rely on prior exposure to be effective. ...
Breaking Medicine Technology: