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Molecular Biomarkers for Cancer Detection and Management
Date:11/7/2013


•Abbott and Stanford University
•Ipsogen and Personal Genome Diagnostics (PDGx)
•Companion diagnostic assay deals
•Abbott and Merck
•Affymetrix and Massachusetts General Hospital (MGH)
•Agilent/Dako and Genentech
•Eli Lilly
•Foundation Medicine
•GE Healthcare and Insight Genetics
•Genomic Health and OncoMed Pharmaceuticals
•HTG Molecular Diagnostics and Merck
•Life Technologies and Others
•Qiagen and Boehringer Ingelheim
•Quintiles and Oxford Cancer Biomarkers
•Roche/Ventana and other companies
•Verastem and Labcorp
•Survey Results

CHAPTER 6: Observations and Conclusions
•Companion diagnostics
•Circulating tumor cells and nucleic acids
•EMT biomarkers
•Tumor Heterogeneity
•Costs and reimbursement

CHAPTER 7: Interview Transcripts
•Luis Diaz, MD, Associate Professor of Oncology, Johns Hopkins School of Medicine; Chief Medical Officer and Founder Personal Genome Diagnostics
•Jorge Nieva, MD, Oncologist and Hematologist,Billings Clinic,Billings Montana
•Harry Glorikian, Managing Partner and Founder, Scientia Advisors
•Paul Dempsey, Ph.D., Chief Science Officer, CynvenioBiosystems
•Scott Kern, M.D., Professor of Oncology and Pathology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine
•About Cambridge Healthtech Institute

TABLES

•Exhibit 4.1 Screening, detection, risk, and monitoring biomarkers
•Exhibit 4.2 Prognosis and prediction biomarkers
•Exhibit 4.3 Companion diagnostic biomarkers
•Exhibit 5.1 Estimated cancer biomarker manufacturer revenues (2012) and projections (2017), by segment (US$ in billions)
•Exhibit 5.2 Selected recent cancer detection, risk, and prognostic assay deals
•Exhibit 5.3 Selected recent companion diagnostic assay deals
•Exhibit 5.4 Survey: Are
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