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Moffitt researchers find adolescents with cancer concerned about their future reproductive health
Date:4/27/2012

Researchers at Moffitt Cancer Center and colleagues have found that adolescents newly diagnosed with cancer have strong concerns about their ability to have children as cancer survivors. They also found that standard health-related quality-of-life survey tools used to elicit answers from teens with cancer did not accurately reflect these concerns. Parents, who often answer survey questions as proxies, often inaccurately relayed their child's reproductive concerns.

The study, carried out by Moffitt researchers and colleagues from the University of South Florida, the University of Florida, All Children's Hospital and Children's Hospital of Orange County Children's Cancer Institute (Orange, Calif.) was published in a recent issue of Pediatrics (129:4). The study was funded by National Institutes of Health grants UL1 DE19587 and UL1 DE019587. It was funded through subcontract from the Oncofertility Consortium at Northwestern University and done in collaboration with Caprice Knapp, Ph.D., a UF researcher and Moffitt member.

According to study lead author Gwendolyn P. Quinn, Ph.D., associate member at Moffitt and director of the Survey Methods Core Facility, in pediatric cancer settings there are occasions when parents act as proxies and answer surveys for their children.

"Our study found inaccuracies in parent-predicted responses of their daughters' reproductive concerns," Quinn said. "Parents often underestimated their daughters' concerns about having children in the future. These parental misperceptions suggest that the health-related quality-of-life survey instruments designed to answer these questions are inappropriate for adolescents with cancer."

To carry out this study, the research team interviewed 14 adolescents ages 12 to 18 who were newly diagnosed with cancer at hospitals in St. Petersburg, Fla., and Orange, Calif. They also interviewed a parent of each patient, in most cases the mothers, who were asked to predi
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Contact: Patty Kim
patty.kim@moffitt.org
813-745-7322
H. Lee Moffitt Cancer Center & Research Institute
Source:Eurekalert

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