Navigation Links
Moffitt researchers find adolescents with cancer concerned about their future reproductive health
Date:4/27/2012

Researchers at Moffitt Cancer Center and colleagues have found that adolescents newly diagnosed with cancer have strong concerns about their ability to have children as cancer survivors. They also found that standard health-related quality-of-life survey tools used to elicit answers from teens with cancer did not accurately reflect these concerns. Parents, who often answer survey questions as proxies, often inaccurately relayed their child's reproductive concerns.

The study, carried out by Moffitt researchers and colleagues from the University of South Florida, the University of Florida, All Children's Hospital and Children's Hospital of Orange County Children's Cancer Institute (Orange, Calif.) was published in a recent issue of Pediatrics (129:4). The study was funded by National Institutes of Health grants UL1 DE19587 and UL1 DE019587. It was funded through subcontract from the Oncofertility Consortium at Northwestern University and done in collaboration with Caprice Knapp, Ph.D., a UF researcher and Moffitt member.

According to study lead author Gwendolyn P. Quinn, Ph.D., associate member at Moffitt and director of the Survey Methods Core Facility, in pediatric cancer settings there are occasions when parents act as proxies and answer surveys for their children.

"Our study found inaccuracies in parent-predicted responses of their daughters' reproductive concerns," Quinn said. "Parents often underestimated their daughters' concerns about having children in the future. These parental misperceptions suggest that the health-related quality-of-life survey instruments designed to answer these questions are inappropriate for adolescents with cancer."

To carry out this study, the research team interviewed 14 adolescents ages 12 to 18 who were newly diagnosed with cancer at hospitals in St. Petersburg, Fla., and Orange, Calif. They also interviewed a parent of each patient, in most cases the mothers, who were asked to predict how their child would answer specific questions concerning fertility and their reproductive concerns for the future.

Audio-taped interviews with patients and parents were carried out separately to ensure that parents did not prompt adolescent answers or prevent their children from expressing their feelings. Fourteen adolescent-parent pairs were interviewed. One of the research objectives was to determine whether health-related quality of instruments intended to capture reproductive concerns was sensitive and appropriate for adolescent patients with cancer.

The interview questions ranged from determining understandings about fertility, to asking if one day the participant would like to have a baby, to "do you feel like you can talk with your parents about fertility" and how would the patient feel if she could not have a baby in the future.

"Sixty-four percent of the parents provided answers that were incongruent with how they predicted their child would answer the questions," explained Quinn. "For example, half of the parents who said their daughter did not want to know about risks to fertility posed by cancer and treatment were also incongruent on five or more statements."

The researchers also found that 75 percent of parents who said that their daughters did not worry about having a baby in the future were also incongruent on more than five other questions.

"Overall, parents underestimated their daughters' reproductive concerns," Quinn said. "The majority of adolescents reported a strong desire for future parenthood, whereas parents expected their daughters to be satisfied with survivorship."

The researchers also concluded that health-related quality-of-life surveys used to establish the reproductive concerns of adolescents by parental proxy reporting are "not suitable for capturing specific emotions and feelings that are impacted by ... a life-threatening illness and long-term goals."

They further noted that researchers should use child self-report whenever possible and that it should be documented when a parent-proxy response has been made.

"Our findings suggest that discussion about future parenting should be encouraged with adolescent patients before they begin treatment," concluded Quinn.


'/>"/>

Contact: Patty Kim
patty.kim@moffitt.org
813-745-7322
H. Lee Moffitt Cancer Center & Research Institute
Source:Eurekalert

Related medicine news :

1. Moffitt Cancer Center researchers working at frontiers of melanoma research
2. Moffitt Cancer Center researchers: Quality of life as important as quantity of life
3. Moffitt researchers find cancer therapies affect cognitive functioning among breast cancer survivors
4. New Moffitt Cancer Center patent promises to accelerate cancer trials
5. Moffitt, Sanford-Burnham and Florida Hospital create Personalized Medicine Partnership of Florida
6. Fibroblasts contribute to melanoma tumor growth, say Moffitt Cancer Center researchers
7. Moffitt Cancer Center researchers find potential target for treating metastatic cancer
8. Moffitt researchers will be strong participants in American Society of Hematology meeting
9. Moffitt Cancer Center researchers find MK1775 active against sarcomas
10. Moffitt Cancer Center researchers find men less willing to be screened for cancer
11. Moffitt Cancer Center researchers unravel biochemical factor important in tumor metastasis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... 2016 , ... Marcy was in a crisis. Her son James, eight, was out of control. ... and physically. , “When something upset him, he couldn’t control his emotions,” remembers Marcy. ... rocks at my other children and say he was going to kill them. If ...
(Date:6/24/2016)... ... June 24, 2016 , ... Global law firm Greenberg Traurig, P.A. announced that ... chosen by their peers for this recognition are considered among the top 2 percent ... special honors as members of this year’s Legal Elite Hall of Fame: Miami ...
(Date:6/24/2016)... CA (PRWEB) , ... June 24, 2016 , ... Comfort ... the American Cancer Society and the Road To Recovery® program to drive cancer patients ... seniors and other adults to ensure the highest quality of life and ongoing independence. ...
(Date:6/24/2016)... , ... June 24, 2016 , ... People across the ... Genome magazine’s Code Talker Award, an essay contest in which patients and their families ... to be presented at the 2016 National Society of Genetic Counselors (NSGC) Annual Education ...
(Date:6/24/2016)... ... 24, 2016 , ... The Haute Beauty Network, affiliated with ... as a prominent plastic surgeon and the network’s newest partner. , Dr. ... handsome men, look naturally attractive. Plastic surgery should be invisible.” He stands by ...
Breaking Medicine News(10 mins):
(Date:6/23/2016)... a startling report released today, National Safety Council research ... proven plan to eliminate prescription opioid overdoses. Prescription Nation ... tackling the worst drug crisis in recorded U.S. history, assigned a ... , New Mexico , Tennessee ... failing states, three – Michigan , ...
(Date:6/23/2016)... , June 23, 2016 Research ... Pharma News Issue 52" report to their offering. ... in influenza treatment creates a favourable commercial environment for MedImmune ... growing patient base that will serve to drive considerable growth ... vaccine would serve to cap sales considerably, but development is ...
(Date:6/23/2016)... the establishment of Astellas Farma Colombia (AFC), a new affiliate with operations headquartered in Bogota. Colombia ... ... Sandra ... ... Astellas is a pharmaceutical company ...
Breaking Medicine Technology: