Navigation Links
Moffitt researchers find adolescents with cancer concerned about their future reproductive health
Date:4/27/2012

Researchers at Moffitt Cancer Center and colleagues have found that adolescents newly diagnosed with cancer have strong concerns about their ability to have children as cancer survivors. They also found that standard health-related quality-of-life survey tools used to elicit answers from teens with cancer did not accurately reflect these concerns. Parents, who often answer survey questions as proxies, often inaccurately relayed their child's reproductive concerns.

The study, carried out by Moffitt researchers and colleagues from the University of South Florida, the University of Florida, All Children's Hospital and Children's Hospital of Orange County Children's Cancer Institute (Orange, Calif.) was published in a recent issue of Pediatrics (129:4). The study was funded by National Institutes of Health grants UL1 DE19587 and UL1 DE019587. It was funded through subcontract from the Oncofertility Consortium at Northwestern University and done in collaboration with Caprice Knapp, Ph.D., a UF researcher and Moffitt member.

According to study lead author Gwendolyn P. Quinn, Ph.D., associate member at Moffitt and director of the Survey Methods Core Facility, in pediatric cancer settings there are occasions when parents act as proxies and answer surveys for their children.

"Our study found inaccuracies in parent-predicted responses of their daughters' reproductive concerns," Quinn said. "Parents often underestimated their daughters' concerns about having children in the future. These parental misperceptions suggest that the health-related quality-of-life survey instruments designed to answer these questions are inappropriate for adolescents with cancer."

To carry out this study, the research team interviewed 14 adolescents ages 12 to 18 who were newly diagnosed with cancer at hospitals in St. Petersburg, Fla., and Orange, Calif. They also interviewed a parent of each patient, in most cases the mothers, who were asked to predict how their child would answer specific questions concerning fertility and their reproductive concerns for the future.

Audio-taped interviews with patients and parents were carried out separately to ensure that parents did not prompt adolescent answers or prevent their children from expressing their feelings. Fourteen adolescent-parent pairs were interviewed. One of the research objectives was to determine whether health-related quality of instruments intended to capture reproductive concerns was sensitive and appropriate for adolescent patients with cancer.

The interview questions ranged from determining understandings about fertility, to asking if one day the participant would like to have a baby, to "do you feel like you can talk with your parents about fertility" and how would the patient feel if she could not have a baby in the future.

"Sixty-four percent of the parents provided answers that were incongruent with how they predicted their child would answer the questions," explained Quinn. "For example, half of the parents who said their daughter did not want to know about risks to fertility posed by cancer and treatment were also incongruent on five or more statements."

The researchers also found that 75 percent of parents who said that their daughters did not worry about having a baby in the future were also incongruent on more than five other questions.

"Overall, parents underestimated their daughters' reproductive concerns," Quinn said. "The majority of adolescents reported a strong desire for future parenthood, whereas parents expected their daughters to be satisfied with survivorship."

The researchers also concluded that health-related quality-of-life surveys used to establish the reproductive concerns of adolescents by parental proxy reporting are "not suitable for capturing specific emotions and feelings that are impacted by ... a life-threatening illness and long-term goals."

They further noted that researchers should use child self-report whenever possible and that it should be documented when a parent-proxy response has been made.

"Our findings suggest that discussion about future parenting should be encouraged with adolescent patients before they begin treatment," concluded Quinn.


'/>"/>

Contact: Patty Kim
patty.kim@moffitt.org
813-745-7322
H. Lee Moffitt Cancer Center & Research Institute
Source:Eurekalert

Related medicine news :

1. Moffitt Cancer Center researchers working at frontiers of melanoma research
2. Moffitt Cancer Center researchers: Quality of life as important as quantity of life
3. Moffitt researchers find cancer therapies affect cognitive functioning among breast cancer survivors
4. New Moffitt Cancer Center patent promises to accelerate cancer trials
5. Moffitt, Sanford-Burnham and Florida Hospital create Personalized Medicine Partnership of Florida
6. Fibroblasts contribute to melanoma tumor growth, say Moffitt Cancer Center researchers
7. Moffitt Cancer Center researchers find potential target for treating metastatic cancer
8. Moffitt researchers will be strong participants in American Society of Hematology meeting
9. Moffitt Cancer Center researchers find MK1775 active against sarcomas
10. Moffitt Cancer Center researchers find men less willing to be screened for cancer
11. Moffitt Cancer Center researchers unravel biochemical factor important in tumor metastasis
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/13/2017)... ... October 13, 2017 , ... The American Board of Family Medicine's (ABFM) Board ... Chief Executive Officer, succeeding Dr. James C. Puffer upon his retirement. Dr. Newton will ... Dr. Puffer’s retirement at the end of 2018. Upon assuming the role of President ...
(Date:10/13/2017)... ... ... Apple Rehab Shelton Lakes , which specializes in the delivery of ... part of a disaster drill on October 3rd. , Apple Rehab participated with the ... as well as the Connecticut Long Term Care Mutual Aid Plan (LTC-MAP). The ...
(Date:10/13/2017)... ... October 13, 2017 , ... Yisrayl Hawkins, Pastor and ... explains one of the most popular and least understood books in the Holy Scriptures, ... puzzling descriptions that have baffled scholars for centuries. Many have tossed it off as ...
(Date:10/12/2017)... Del. (PRWEB) , ... October 12, 2017 , ... ... and advisory services for healthcare compliance program management, will showcase a range of ... National Association for Assisted Living (NCAL) Convention and Expo to be held October ...
(Date:10/12/2017)... ... , ... The American College of Medical Informatics (ACMI) will present the 2017 ... Session of AMIA’s Annual Symposium in Washington, D.C. AMIA’s Annual Symposium is ... pioneer in the field of medical informatics, this prestigious award is presented to an ...
Breaking Medicine News(10 mins):
(Date:10/11/2017)... , Oct. 11, 2017  Caris Life Sciences ® ... fulfilling the promise of precision medicine, today announced that ... Caris, Precision Oncology Alliance™ (POA) as its 17 th ... the St. Jude Crosson Cancer Institute will help develop ... use of tumor profiling, making cancer treatment more precise ...
(Date:10/10/2017)... , Oct. 10, 2017   West Pharmaceutical ... innovative solutions for injectable drug administration, today shared the ... ID Adapter for improving the intradermal administration of polio ... Skin Vaccination Summit in May 2017 by Dr. ... Polio Department, World Health Organization (WHO), and recently published ...
(Date:10/4/2017)... WESTWOOD, Mass. , Oct. 4, 2017  According to the Centers ... by the end of October . PhysicianOne Urgent Care is helping communities ... Westchester, NY , by offering no-cost* flu shots through ... , as mandated by certain health insurance regulations. ... The best time to get a flu shot is by ...
Breaking Medicine Technology: