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Moffitt researcher awarded GE grant to develop tool to detect breast cancer metastasis genetic risks
Date:4/27/2012

who did not develop metastatic disease after five years of follow-up.

The task for Moffitt researchers will be to evaluate inherited changes in DNA that are predictive for and identify inherited risk for developing or resisting breast cancer metastasis.

"We hope to identify biologic markers of metastasis to help classify those facing a higher metastasis risk," Lee said. "We also aim to improve therapeutic decision-making and ability to better predict outcomes after a breast cancer diagnosis."

The study falls under Moffitt's mission to offer personalized medicine to patients, a treatment plan by which an individual's disease is treated based on the patient's unique genetic makeup.

"Our ultimate goal is to develop a cheek swab test for patients diagnosed with breast cancer to be able to quickly guide treatment decisions based on their inherited predisposition to develop advanced disease," Lee said.

The Moffitt research team on the grant includes Johnathan Lancaster, M.D., Ph.D.; Ya-Yu Tsai, Ph.D.; and Thomas Sellers, Ph.D., M.P.H., Moffitt executive vice president and director of the Moffitt Research Institute. The research team is also collaborating with laboratories at the National Cancer Institute in Washington, D.C.


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Contact: Patty Kim
patty.kim@moffitt.org
813-745-7322
H. Lee Moffitt Cancer Center & Research Institute
Source:Eurekalert

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