Navigation Links
Moffitt Cancer Center researchers validate molecular signature to predict radiation therapy benefit
Date:8/15/2012

ed five-year, relapse-free survival when compared to radioresistant patients.

"This study validated RSI in 503 patients in two independent data sets," Torres-Roca said. "We have validated RSI in five independent cohorts totaling 621 patients, so this latest validation study, to the best of our knowledge, makes this technology the most extensively validated molecular signature in radiation oncology."

The successful transition from applying the technology to cell lines to patient application also suggests that the biological basis of cellular radiosensitivity is conserved between cell lines and patients and also across epithelial tumors, Torres-Roca said.

"We propose that RSI is a predictive biomarker of radiation therapy therapeutic benefit for patients with breast cancer," Torres-Roca said. "This novel biomarker provides an opportunity to integrate individual tumor biology with clinical decision-making in radiation oncology."


'/>"/>
Contact: Kim Polacek
kim.polacek@moffitt.org
813-745-7408
H. Lee Moffitt Cancer Center & Research Institute
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Moffitt Cancer Center researchers discover how cancer cells hijack a mechanism to grow
2. Attitudes toward outdoor smoking ban at moffitt Cancer Center evaluated
3. Moffitt Cancer Center researcher & colleagues test new drug for patients with neuroendocrine tumors
4. Moffitt Cancer Center researchers find potential key to new treatment for mantle cell lymphoma
5. Moffitt Cancer Center study validates activity of rare genetic variant in glioma
6. Moffitt researchers find cutaneous human papillomavirus infection a risk factor for skin cancer
7. Moffitt Cancer Center researchers test drug combinations to prevent graft vs. host disease
8. Sun exposure and cutaneous HPV infection found synergistic in skin cancers, Moffitt says
9. Myelodysplastic syndrome treated with deferasirox shows beneficial iron reduction, Moffitt says
10. Moffitt researchers: Darwins principles say cancer will always evolve to resist treatment
11. Moffitt researcher, colleagues find success with new immune approach to fighting some cancers
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/1/2015)... ... September 01, 2015 , ... ... D.O., has joined its medical management team as an Associate Medical Director. ... sizes and types in the U.S. and abroad. , Dr. Nelson has ...
(Date:9/1/2015)... ... September 01, 2015 , ... Agriculture innovation, urban farming, local ... the topics to be discussed at Seedstock’s 4th Annual Sustainable Agriculture Conference : ... San Diego. , In addition to keynotes Pierre Sleiman, founder and CEO of ...
(Date:9/1/2015)... (PRWEB) , ... September 01, 2015 , ... ... Connectivity Kit is now available. With the Connectivity Kit, EasySampler data ... automated jacketed lab reactor control experiment, on a touchscreen platform. , EasySampler fully ...
(Date:9/1/2015)... ... September 01, 2015 , ... CanAm ... investor-families have received permanent green cards (I-829 petition approval) from the USCIS through ... is the final step of the EB-5 visa process for immigrant investors to ...
(Date:9/1/2015)... (PRWEB) , ... September 01, 2015 , ... ... cards, launched its consumer-friendly, informational video this week to coincide with back-to-school and ... . , According to the CDC, elementary school children are sick an ...
Breaking Medicine News(10 mins):Health News:Dr. Brent Nelson Joins WorkCare, Inc., as Associate Medical Director 2Health News:Dr. Brent Nelson Joins WorkCare, Inc., as Associate Medical Director 3Health News:Experts in Urban and Local Food Systems Development to Address Seedstock Sustainable Agriculture Conference Nov. 3-4 Discounted ticket sales end Sept. 4 2Health News:Experts in Urban and Local Food Systems Development to Address Seedstock Sustainable Agriculture Conference Nov. 3-4 Discounted ticket sales end Sept. 4 3Health News:Experts in Urban and Local Food Systems Development to Address Seedstock Sustainable Agriculture Conference Nov. 3-4 Discounted ticket sales end Sept. 4 4Health News:Experts in Urban and Local Food Systems Development to Address Seedstock Sustainable Agriculture Conference Nov. 3-4 Discounted ticket sales end Sept. 4 5Health News:New Technology Allows Unattended Sampling and Synthesis of Chemical Reactions 2Health News:New Technology Allows Unattended Sampling and Synthesis of Chemical Reactions 3Health News:CanAm Enterprises Reaches Another Milestone with More Than 1,500 I-829 Petition Approvals 2Health News:USA Medical Card Launches New FAQ Video During Back-to-School 2
... This release is available in French . ... suffering from two serious autoimmune disorders which cause muscular ... says a group of Montreal researchers. Dr. Christian A. ... the McGill University Health Centre (RI-MUHC) have linked muscular ...
... , , CHICAGO, Sept. 1 ... hitting the pavement more often in the hunt for a new job! ... showing on their face - during an interview is foot pain. ... Tsatsos, of AnkleNFootCenter.com. "And dress shoes are the worst, particularly for ...
... , , HARRISBURG, Pa., ... if they are interested in receiving pandemic H1N1 influenza vaccines ... of Health said today. , , ... hospitals, clinics, pharmacists, schools and community vaccinators. , ...
... PITTSBURGH, Sept. 1 On Friday, September 18, at noon WQED ... the renowned public relations agency Porter Novelli, former CEO of the ... D. Novelli. Enjoy lunch and a presentation on the benefits ... and what it means for seniors in the future. Mr. ...
... , Springfield AARP Volunteers Deliver ... Congressmen to Tackle Issue , , SPRINGFIELD, ... a break from Washington, AARP is making sure they don,t get ... system. With a giant inflatable Rx bottle as a backdrop, ...
... , , ... of innovative voice data solutions, today announced the availability ... services. NotifierRx will help hospitals improve standards of care ... with interactive voice-controlled services. , , ...
Cached Medicine News:Health News:Researchers link inflammatory diseases to increased cardiovascular risk 2Health News:Hitting the Pavement? Make Sure Your Feet (And Your Shoes) Are Ready. 2Health News:Pennsylvania Department of Health Launches Online H1N1 Vaccine Registry 2Health News:Sen. Durbin, Congressmen Get Health Care Reform 'Message in a Bottle' from AARP 2Health News:Audiopoint Adds Voice to Healthcare Reform Debate 2Health News:Audiopoint Adds Voice to Healthcare Reform Debate 3
(Date:8/31/2015)... Aug. 31, 2015  Chiasma, Inc. (NASDAQ: ... octreotide capsules for the orphan condition acromegaly, today ... June 30, 2015 and provided a corporate update. ... a transformative time for Chiasma, as we successfully ... that our first New Drug Application (NDA) has ...
(Date:8/31/2015)... 2015 A new Transparency ... monitoring and diagnostic devices market stood at US$3.7 ... a value of approximately US$7.0 billion in 2019, ... and 2019. The title of the report is ... Monitors, Event Monitors, Cardiovascular Diagnostic Catheters, Implantable Loop ...
(Date:8/31/2015)... YORK , Aug. 31, 2015  Dipexium Pharmaceuticals, ... focused on the development and commercialization of Locilex® (pexiganan ... today announced plans to participate in four investor conferences ... 2, 2015 at the Sidoti & Company, LLC Emerging ... . David P. Luci , President & ...
Breaking Medicine Technology:Chiasma Reports Second Quarter 2015 Financial Results and Recent Business Highlights 2Chiasma Reports Second Quarter 2015 Financial Results and Recent Business Highlights 3Chiasma Reports Second Quarter 2015 Financial Results and Recent Business Highlights 4Chiasma Reports Second Quarter 2015 Financial Results and Recent Business Highlights 5Chiasma Reports Second Quarter 2015 Financial Results and Recent Business Highlights 6Chiasma Reports Second Quarter 2015 Financial Results and Recent Business Highlights 7Chiasma Reports Second Quarter 2015 Financial Results and Recent Business Highlights 8Chiasma Reports Second Quarter 2015 Financial Results and Recent Business Highlights 9Cardiovascular Monitoring and Diagnostic Devices Market to Reach US$7.0 Billion in 2019 Owing to Global Rise in Diabetes and Obesity: Transparency Market Research 2Cardiovascular Monitoring and Diagnostic Devices Market to Reach US$7.0 Billion in 2019 Owing to Global Rise in Diabetes and Obesity: Transparency Market Research 3Cardiovascular Monitoring and Diagnostic Devices Market to Reach US$7.0 Billion in 2019 Owing to Global Rise in Diabetes and Obesity: Transparency Market Research 4Cardiovascular Monitoring and Diagnostic Devices Market to Reach US$7.0 Billion in 2019 Owing to Global Rise in Diabetes and Obesity: Transparency Market Research 5Dipexium Pharmaceuticals Announces Participation in Four Investor Conferences in September 2Dipexium Pharmaceuticals Announces Participation in Four Investor Conferences in September 3
... announces the appointment of Susan C. Stansfield, PhD ... Development. In this position, Dr. Stansfield will have ... clinical trial management services provided to the biopharmaceutical ... proven leadership skills will be pivotal in enhancing ...
... Reportlinker.com announces that a new market research ... E7: The Outlook for Pharmaceuticals to ... The emerging E7 countries represent the ... these countries is huge: they have a ...
Cached Medicine Technology:Premier Research Names Susan Stansfield, PhD Executive VP, Clinical Development 2E7: The Outlook for Pharmaceuticals to 2012 2E7: The Outlook for Pharmaceuticals to 2012 3E7: The Outlook for Pharmaceuticals to 2012 4E7: The Outlook for Pharmaceuticals to 2012 5
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: