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Modulated radiotherapy can cut treatment time for cancer of the rectum without increasing toxicity
Date:6/16/2008

Application of modulated radiotherapy in the treatment of bowel cancer can enhance the results obtained by means of other conventional therapies. The technique has managed to apply the radiation in a way most adapted to the tumoral volume and risk areas, while minimising irradiation to healthy tissue. This radiotherapy procedure involves the administration of higher daily doses of radiation but with a total dose equivalent to conventional ones. In this way the treatment time is cut by 30%, without a rise in side effects and with very high rates of pathological response.

These were the results of the study undertaken by a team of doctors at the University Hospital of Navarra, recently published in the specialist scientific journal, "International Journal of Radiation Oncology, Biology, Physics" of the American Society for Therapeutic Radiotherapy and Oncology. Involved in the research was a medical team from the area of digestive system tumours, led by Doctor Jos Javier Aristu, specialist at the Oncological Radiology Service. The article in the North American journal is the first published in the world giving clinical results from the application of preoperational modulated radiotherapy in tumours of the rectum.

Novelty for cancer of the rectum

IMRT (Intensity-Modulated Radiation Therapy) is a radiotherapy technique in which the administration of the radiation doses for the patient is effected by means of a lineal accelerator equipped with a system of multilaminas. Depending on the characteristics of the region that has to be irradiated, the planning system is capable of adapting high radiation doses to the shape of the target volume, enabling adjustments to be made to the morphology of the area to be treated in an individualized manner.

To date, the application of this procedure had been fundamentally limited to tumours located in the head, neck and prostrate gland. "This technique had been used in more confined tumour
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Contact: Irati Kortabitarte
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Elhuyar Fundazioa
Source:Eurekalert

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