Navigation Links
Modified vaccine shows promise in preventing malaria
Date:9/26/2011

>

Those genetic agents, similar to chemical adjuvants, are stimulants that improve the ability of vaccines to induce beneficial immune responses in general.

In mouse models, the researchers used two such "gene-adjuvants": rEA and EAT-2, both of which aimed to illicit improved immune responses to the malaria CSP gene. Surprisingly, the rEA agent which was developed at MSU in part by the late Barnett Rosenberg did not produce the desired result and in fact seemed to worsen the animal's ability to generate an immune response to CSP.

However, the EAT-2 gene-adjuvant stimulated the immune system in a different way, and Amalfitano and his team were able to increase the ability of the immune system to respond to CSP to a level that surpassed currently available malaria vaccine systems.

"The results were surprising, but we were able to hit our goal eventually," he said. "This research will help us as we create a viable vaccine. While the way that rEA is trying to stimulate the immune system may not be the best way for malaria, we did come up with an alternative adjuvant to effectively target the parasite."

Amalfitano said the next step is to see if researchers can prevent malaria in animal models using the EAT-2 gene-adjuvant: "Then we can take the lessons learned and really go forward and do what's necessary to feel confident to begin human trials."


'/>"/>

Contact: Jason Cody
codyja@msu.edu
517-432-0924
Michigan State University
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. NIH Stem Cell Guidelines Should Be Modified, UCSF Team Reports
2. Adults demonstrate modified immune response after receiving massage, Cedars-Sinai researchers show
3. New On the Menu: Genetically Modified Salmon?
4. FDA Advisers Weigh Approval of Genetically Modified Salmon
5. FDA Advisers Consider Approval of Genetically Modified Salmon
6. Consumer Activists Want Modified Salmon to Be Labeled
7. Save messengers -- modified mRNAs open up new therapeutic possibilities
8. Gene-modified stem cells help protect bone marrow from toxic side effects of chemotherapy
9. Vaccine May Prevent TB in People With HIV
10. Vaccine Not Fail-Safe in Ongoing Mumps Outbreak
11. New strategy produces promising advance in cancer vaccines
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Modified vaccine shows promise in preventing malaria
(Date:5/29/2015)... 29, 2015 On May 21, 2015, Elle ... When You Get Botox ?” reported on the four ... Elle partnered with Google to determine these results and then ... question in California, for example, is how to keep ... search query is what's the appropriate age to start receiving ...
(Date:5/29/2015)... May 29, 2015 Jan Wooden Howse lost ... one thing above all else: God does no wrong. , ... of her son’s passing is titled “God Does No Wrong.” ... confronted with great personal tragedy. , “My story has ... dear to you into something productive, something healing,” Howse said. ...
(Date:5/29/2015)... York, NY (PRWEB) May 29, 2015 ... unit have reached a confidential Risperdal lawsuit ( ... allegedly developed gynecomastia due to his use of ... case had been selected for the third bellwether ... a mass tort litigation underway in Pennsylvania’s Philadelphia ...
(Date:5/29/2015)... Diego, California (PRWEB) May 29, 2015 A ... Core” and have joined the national effort to teach this ... parents in the U.S. have been “sickened” by the recent ... However, love it or hate it, Common Core is now ... District of Columbia. Parents are now seeking ways to ...
(Date:5/29/2015)... (PRWEB) May 29, 2015 ... recently partnered with Stratus Video Interpreting ... will facilitate better communication and timely care ... and hearing loss. Stratus’ video remote interpreting ... translators, enabling staff to quickly access qualified ...
Breaking Medicine News(10 mins):Health News:Botox, Wrinkles and Double Chins: The Most-Asked Beauty Problems According to Google 2Health News:Turning grief from a child’s passing into virtue 2Health News:Risperdal Lawsuit Selected as Pennsylvania’s Third Bellwether Gynecomastia Case Settles Hours Before Trial 2Health News:Risperdal Lawsuit Selected as Pennsylvania’s Third Bellwether Gynecomastia Case Settles Hours Before Trial 3Health News:Doctors Discover a Cure for the Common Core 2Health News:Stratus Video Interpreting Partners With Intermountain Healthcare to Provide On-Demand Interpretation Services for Patients With Limited English Proficiency (LEP) 2Health News:Stratus Video Interpreting Partners With Intermountain Healthcare to Provide On-Demand Interpretation Services for Patients With Limited English Proficiency (LEP) 3Health News:Stratus Video Interpreting Partners With Intermountain Healthcare to Provide On-Demand Interpretation Services for Patients With Limited English Proficiency (LEP) 4
... an assistant professor at the University of Miami, School ... grant from the Robert Wood Johnson Foundation (RWJF) to ... dating violence among Hispanics. Gonzalez-Guarda is one of just ... the three-year $350,000 Nurse Faculty Scholar award this year. ...
... , WEDNESDAY, Sept. 7 (HealthDay News) -- Breast-feeding ... mothers who bottle-feed or women without children, researchers say. ... mothers and 20 non-mothers also found that aggression in ... This suggests that breast-feeding helps lower the body,s typical ...
... who have received high doses of chemotherapy may find ... research from the Sahlgrenska Academy at the University of ... chemotherapy treatment were two times higher than among those ... the scientific journal Acta Oncologica . Almost one ...
... concerns may prevent children from getting good exercise, according ... examined how families use neighborhood parks. Results ... too closely by hovering "helicopter" parents were less likely ... "It,s a catch-22 for today,s parents, unfortunately. Many ...
... By Ellin Holohan HealthDay Reporter , WEDNESDAY, Sept. ... jeopardize their children,s academic success and harm their family,s finances ... money on cigarettes, according to a new study. The ... with smokers have higher rates of respiratory illness and missed ...
... Reporter , TUESDAY, Sept. 6 (HealthDay News) -- Contrary ... and breast self-exams are useful for the detection of ... screening mammographies and evaluations of palpable masses are important ... co-author of a study to be presented at the ...
Cached Medicine News:Health News:UM Gonzalez-Guarda wins grant from Robert Wood Johnson Foundation 2Health News:UM Gonzalez-Guarda wins grant from Robert Wood Johnson Foundation 3Health News:Chemotherapy can impair speech 2Health News:Helicopter parents can impede child’s ability to play 2Health News:Parents Who Smoke at Home May Risk Kids' Academic Success 2Health News:Parents Who Smoke at Home May Risk Kids' Academic Success 3Health News:Annual Breast Exams, Mammograms Still Key to Detecting Breast Cancer 2Health News:Annual Breast Exams, Mammograms Still Key to Detecting Breast Cancer 3
(Date:5/29/2015)... Mass. , May 29, 2015  Hologic, Inc. ... has entered into a new, five-year secured credit agreement ... a $1 billion revolving credit facility. Hologic ... and used these proceeds and the Term Loan to ... which had an aggregate principal amount outstanding of $1.69 ...
(Date:5/29/2015)... 29, 2015  Today, UL LLC, a global ... provider of electronic quality management systems (EQMS) and ... will leverage the strengths of both organizations to ... implementation and comprehensive advice and guidance for successful ... capabilities to UL,s strength in regulatory services and ...
(Date:5/29/2015)... Fla. , May 29, 2015  Excite Medical ... in 2007.  Over the years, Excite Medical, under the ... be an enduring company, with a solid track record ... and growing client and distributor base.  ... success of Excite Medical has been possible, in large ...
Breaking Medicine Technology:Hologic Enters into Five-Year Secured Credit Agreement 2Hologic Enters into Five-Year Secured Credit Agreement 3UL and MasterControl collaborate to provide medical manufacturers full service QMS and Regulatory Submissions support 2UL and MasterControl collaborate to provide medical manufacturers full service QMS and Regulatory Submissions support 3
... Conatus Pharmaceuticals Inc. today announced the closing of ... financing.  This financing was led by new investor, AgeChem ... existing investors; Aberdare Ventures, Advent Venture Partners, Bay City ... will use the proceeds to advance the clinical development ...
... Mindray Medical International Limited (NYSE: MR), a leading developer, ... that it will report its financial results for the ... market closes on February 28, 2011. Mindray,s management will ... March 1, 2011 U.S. Eastern Time (9:00 PM on ...
Cached Medicine Technology:Conatus Pharmaceuticals Completes $20 Million Series B Private Placement Financing 2Mindray to Report Fourth Quarter and Full Year 2010 Financial Results on February 28, 2011 2
... Cronin, Inc. is a ... Footwear, Orthopedic Softgoods, and ... Our products are of ... available in the USA ...
... 3-Point® Polycentric Hinged Ulnar Deviation Splint ... align the hand with ulnar deviation at ... impede grasp or pinch. Radial and ulnar ... ensure unimpeded flexion and extension. Padded, malleable ...
... immobilizes and positions the elbow at 122 ... prominent. Restricts full extension and flexion to ... helps prevent pain and irritation due to ... post-cast removal. Rigid, high-density beige polyethylene shell ...
... Orthosis For quick, efficient immobilization of ... immobilizes and protects the fracture and ... comfort, support, and conformity to the ... shell may be gently heated (with ...
Medicine Products: