Navigation Links
Modified Polio Virus May Help Fight Brain Tumors, Study Suggests
Date:5/23/2013

THURSDAY, May 23 (HealthDay News) -- A modified version of the polio virus might one day help fight brain tumors, preliminary research suggests.

Scientists at Duke Cancer Institute said the investigational therapy, known as PVSRIPO, uses an engineered form of the virus that is harmless to normal cells, but attacks cancer cells. The therapy shows promise in the treatment of glioblastoma, the most common and aggressive brain tumor, they said.

"These early results are intriguing," principal investigator Dr. Annick Desjardins, an associate professor of medicine at Duke University School of Medicine, said in a news release. "Current therapies for glioblastoma are limited because they cannot cross the blood-brain barrier and often do not specifically attack the tumor. This treatment appears to overcome those problems."

The findings are scheduled for presentation at the American Society of Clinical Oncology annual meeting in Chicago, from May 31 to June 4.

Researchers at Duke said they developed the therapy to take advantage of the fact that cancer cells have receptors that attract the polio virus. The virus infects and kills the tumor cells. When infused into a tumor, the therapy also triggers the immune system to attack the infected tumor cells, the researchers said.

Of seven patients involved in the preliminary study, three have responded well to the therapy. One year after treatment, one of the three patients remains cancer-free. Another is disease-free after 11 months; a third has been cancer-free for five months. Two others are also disease-free. Only two patients in the study did not respond well to the therapy, the study authors said.

In contrast, the researchers noted that about 50 percent of glioblastoma patients have a recurrence of their disease within eight weeks of traditional treatments.

Studies presented at meetings should be considered preliminary until published in a peer-reviewed medical journal.

More information

The American Brain Tumor Association provides more information on glioblastomas.

-- Mary Elizabeth Dallas

SOURCE: Duke Medicine, news release, May 21, 2013


'/>"/>
Copyright©2012 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Modified Burpee Bodyweight Exercise Video Released by Bodyweight Torch
2. Modified Plank Core Exercise Video Revealed By Bodyweight Torch
3. Repairing articular cartilage defects with an injectable gel engineered with gene modified BMSCs
4. Almost Nuts! Supports Whole Foods Decision on Banning Gentically Modified Salmon and Continues to Support the Movement Against Genetically Engineered Foods
5. Zane Benefits Publishes New Information on Health Care Reform and Adjusted Gross Income (AGI) vs. Modified AGI
6. Genetically modified tobacco plants produce antibodies to treat rabies
7. Almost Nuts! a Wisconsin Company Innovates Healthy Snack Foods that are Not Genetically Modified
8. Studies assess genetics, modified treatment to improve outcomes, reduce toxicity
9. Regulatory science for public health: From functional food to modified-risk tobacco products
10. Genetically modified T cell therapy shown to be safe, lasting in decade-long study of HIV patients
11. Poliovirus vaccine trial shows early promise for recurrent glioblastoma
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Modified Polio Virus May Help Fight Brain Tumors, Study Suggests
(Date:10/13/2017)... LUIS OBISPO, Calif. (PRWEB) , ... October 13, 2017 , ... ... Alzheimer’s or dementia. However, many long-term care insurance companies have a waiver for care ... is the 90-day elimination period, when the family pays for care, is often waived, ...
(Date:10/13/2017)... ... 2017 , ... Talented host, actor Rob Lowe, is introducing ... new episode of "Success Files," which is an award-winning educational program broadcasted on ... subject in-depth with passion and integrity. , Sciatica occurs when the sciatic nerve ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... now treating sleep apnea using cutting-edge Oventus O2Vent technology. As many ... sleep disorder characterized by frequent cessation in breathing. Oral appliances can offer significant ...
(Date:10/12/2017)... ... , ... Asante, a nationally recognized health system in southern ... home health joint venture through an agreement, effective October 1, 2017, to create ... health company with Asante, delivering clinically integrated care, for the past eight years. ...
(Date:10/12/2017)... ... ... On Saturday, October 21, the Health & Wellness Center at Florida Hospital ... for the American Heart Association Heart Walk. Teams of up to 10 people can ... their treadmills moving for 5 hours. Treadmills will start at 7:00 p.m. on Saturday, ...
Breaking Medicine News(10 mins):
(Date:10/7/2017)... , Oct. 6, 2017   Provista, ... more than $100 billion in purchasing power, today announced ... and information. The Newsroom is the online ... industry trends, infographics, expert bios, news releases, slideshows and ... access to a wealth of resources at their fingertips, ...
(Date:10/4/2017)... 2017 OBP Medical , a ... devices, today announced regulatory approval from ... Agência Nacional de Vigilância Sanitária (ANVISA)) to market ... retractor with integrated LED light source and smoke ... exposure of a tissue pocket or cavity during ...
(Date:10/2/2017)... -- Halo Labs announces the European launch of their new low ... MIBio 2017 in Cambridge, U.K on October ... biopharmaceutical samples with unprecedented speed and sensitivity while using far less ... Imaging. ... analysis system ...
Breaking Medicine Technology: