Navigation Links
Modeling disparities may help with cervical cancer prevention

Researchers reported that explicit inclusion of disparities in cost-effectiveness analysis, would allow policy makers to identify strategies that would reduce overall cancer risk, reduce disparities between racial ethnic subgroups, and be cost-effective, according to a study published online September 6 in the Journal of the National Cancer Institute.

Disease simulation models can be used to identify effective and cost-effective strategies for reducing overall cancer incidence and mortality, but are sometimes criticized for not considering how the benefits are distributed within the population. Advances in computer-based modeling, together with the availability of better data, allows details to now be included that account for inequalities between different population subgroups.

To provide a framework for how health inequities could be more explicitly considered in model-based cost-effectiveness analysis, Sue J. Goldie, MD, MPH, and Norman Daniels, Ph.D., of the Harvard School of Public Health, devised a typology of cancer disparities among black, white, and Hispanic populations in the United States that differentiated inequalities resulting from different factors, such as access and quality of treatment and prevention. They used this typology to guide an evaluation of different cervical cancer screening and vaccination strategies in which the health and economic outcomes were calculated for the average population, and also for the three racial subgroups separately.

The researchers identified strategies that reduced the overall risk of cervical cancer from 60% to 74.5%, and that improved cancer outcomes in all racial subgroups. However, they also found that the benefits were unequally distributed; for example, while current screening patterns would resulted in a 60% reduction in overall cancer incidence, reductions ranged from 54.8% for Hispanic women to 62.5% for white women.

The researchers found that screening strategies that directly targeted racial subgroups bearing the greatest inequalities, when combined with vaccination, provided a more equitable distribution of benefits. For example, reduction in cervical cancer incidence was 69.7% in white women versus 70.1% in Hispanic women. These strategies were also more effective and less costly than current screening patterns.

The authors conclude that modeling disparities in cancer prevention can identify strategies that will improve overall population health, distribute health benefits fairly, and utilize health care resources efficiently. They write, "These points of convergence are 'win-win' in the sense that they have the biggest positive impact in worst-off groups as well as on population health overall.

Our claim is that such win-win strategies are most desirable from the perspective of both goals of health policy, population health improvement, and health equity."

In an accompanying editorial, Kevin A. Ault, M.D., of the Department of Gynecology and Obstetrics at Emory University School of Medicine writes that the introduction of the HPV vaccines into the world of medicine has made cervical cancer prevention a reality. Ault agrees with the study's conclusions on the utility of modeling, particularly that, "modeling of racial and ethnic subgroups at increased risk identifies strategies that can reduce cancer burden among these groups." Ault adds that since recent research has identified HPV vaccination and diagnostic testing as potential improvements to the Pap smear in cervical cancer prevention, these strategies should be made available to all women.


Contact: Zack Rathner
Journal of the National Cancer Institute

Related medicine news :

1. Hunk Calendar Photographer Resurrects Erotic Male Modeling Club and Launches Provocative E-exhibition
2. PivotPoint Doubles Down on Business Process Modeling with Advanced BPMN 2 + UML 2 Training
3. Solid tumor modeling focus of workshops
4. Tutorial addresses multi-cell, multi-scale modeling
5. INFORMS health care conference highlights increased role of math modeling in health systems
6. Racial disparities persist in the diagnosis of advanced breast cancer and colon cancer in the U.S.
7. U.S. Surgeon General Regina Benjamin to Address National Association of Black Journalists Conference on Health Disparities
8. New, National Amnesty International Report Finds Appalling U.S. Death Rate for Women Having Babies, Systemic Failures and Shocking Disparities in Maternal Health Care System; Louisiana is 46th Among All States in Maternal Mortality
9. New, National Amnesty International Report Finds Appalling U.S. Death Rate for Women Having Babies, Systemic Failures and Shocking Disparities in Maternal Health Care System; Georgia is 50th Among All States in Maternal Mortality
10. New, National Amnesty International Report Finds Appalling U.S. Death Rate for Women Having Babies, Systemic Failures and Shocking Disparities in Maternal Health Care System; Maryland is 48th Among All States in Maternal Mortality
11. New, National Amnesty International Report Finds Appalling U.S. Death Rate for Women Having Babies, Systemic Failures and Shocking Disparities in Maternal Health Care System; District of Columbia is 51st Among All States in Maternal Mortality
Post Your Comments:
(Date:11/30/2015)... ... , ... According to Los Angeles bariatric surgeon Michael Feiz, M.D., F.A.C.S., many ... real hunger, but instead by a hormone called ghrelin which (often prematurely) signals ... are aware that weight loss surgery can help patients lose weight by restricting the ...
(Date:11/30/2015)... Miami, FL (PRWEB) , ... November 30, 2015 ... ... added a comparison chart and ingredient list of its hemorrhoid ointment to its ... “fast, effective pain relief for people suffering from hemorrhoids. Adding the comparison chart ...
(Date:11/30/2015)... ... November 30, 2015 , ... Using a combination of two blood sugar tests ... adults, according to a new study by researchers at the School of Public Health ... Adults: Using Combinations of Blood Glucose Tests ,” published in Frontiers in Public Health, ...
(Date:11/30/2015)... ... November 30, 2015 , ... The recently ... Poison Data System (NPDS) reveals that in 2014, someone called a poison center ... two million of which were human exposure cases. , The American Association of ...
(Date:11/30/2015)... Reading, PA (PRWEB) , ... November 30, 2015 ... ... Ashland Specialty Ingredients (ASI) as their exclusive channel partner for the Nutraceutical Specialties ... supplements markets in the US, effective immediately. , “We are pleased to ...
Breaking Medicine News(10 mins):
(Date:11/30/2015)... Next week, December 2-3, BIOMEDevice San ... co-located events covering the latest in Medtech innovation, Wearable ... draw more than 3,000 design industry professionals to the ... events, combined show floor will host more than 300 ... --> --> BIOMEDevice features suppliers in ...
(Date:11/30/2015)...  IBA Molecular North America, Inc. (IBAMNA), a U.S. ... that as of January 1, 2016, it will do ... to rebrand the company reflects a refined vision for ... close relationship with Zevacor Molecular.  Both IBAMNA and Zevacor ... Peter Burke , Vice President Sales ...
(Date:11/30/2015)... , Nov. 30, 2015 Nautilus Medical Inc. ... Image Management platform ( ). The release of ... from RSNA 2015 (Radiology Society North America) in ... in the U.S. --> ... that enables access to radiology studies worldwide via a ...
Breaking Medicine Technology: